Age-specific Dermatology evidence for mixed — concise summaries and practical next steps.
Speed diagnosis and treatment for Latino patients with melanoma by ensuring linguistically appropriate care and supporting patient advocacy, while...
Clinical insightMonopolar RF can improve mid–lower face laxity metrics and reduce oiliness over 2–24 weeks in adults with skin types III–V, with mostly mild,...
Clinical insightPretreatment NLR ≥2.54, PLR ≥117, and LMR ≤3.69 are simple blood-based markers that may help flag higher risk of disease-specific death in EMPD and...
Clinical insightFrequent painful or blistering sunburns—especially in childhood—are linked with higher odds of cSCC; emphasize prevention of severe sunburns and...
Clinical insightIn CSU clinics, expect higher burden and poorer control in women—especially those aged 51–65—and proactively assess angioedema, systemic symptoms,...
Clinical insightExpect accelerated epigenetic aging in psoriatic arthritis, while psoriasis alone may not; signals are also seen in pediatric atopic dermatitis and...
Clinical insightIn routine care, ICIs yield limited but measurable benefit in advanced mucosal melanoma, with first‑line median PFS ~9 months and OS ~26 months. Set...
Clinical insightPatients from lower-SES neighborhoods had higher adjusted odds of receiving a new HS diagnosis in this health system. Consider neighborhood context...
Clinical insightIn outpatient clinics using compression, OFM was associated with faster and more frequent VLU closure than collagen/ORC at 24–36 weeks. Consider OFM...
Clinical insightOver 8 weeks, both an oral synbiotic and a myoinositol‑based herbal supplement were associated with fewer acne lesions and higher SCFAs; the...
Clinical insightHigher PM10 was associated with lower odds of melanoma (OR 0.89, 95% CI 0.86–0.92; p<0.001) and higher PM2.5 with lower odds (OR 0.72, 95% CI...
Key findingPrioritize achieving an adequate cumulative isotretinoin dose to lower relapse and the need for retrial; increasing daily dose above conventional...
Clinical insightExpect a higher rate of incident psoriasis with immune checkpoint inhibitors than with chemotherapy or targeted therapies; monitor and counsel...
Clinical insightHome narrowband UV-B was as effective as office-based therapy at 12 weeks, including across all skin phototypes, with higher adherence but more...
Clinical insightIn Sweden, melanoma incidence and mortality have recently fallen in adults 30–49, while incidence continues to rise in those 50–59 and mortality has...
Clinical insightZasocitinib ≥5 mg daily improved skin clearance vs placebo over 12 weeks in moderate to severe plaque psoriasis, with similar short-term safety and...
Clinical insightSeborrheic dermatitis affects about 4% of people worldwide, with higher rates in adults and wide regional variation; local prevalence may differ...
Clinical insightIn older men with cutaneous vasculitis, neutrophilic dermatoses, or chondritis, consider testing for VEXAS (UBA1). Prednisone often improves skin...
Clinical insightAbrocitinib monotherapy produced large 12-week itch reductions and quality-of-life gains in PN and CPUO with few adverse events in this small study;...
Clinical insightMultiple onychopapillomas across several nails are common in adults with BAP1 TPDS and may be a practical clinical clue to identify the syndrome in...
Clinical insightExpect terbinafine failure associated with SQLE mutations and elevated MICs in T indotineae; in this series, itraconazole led to clearance or...
Clinical insightIn high‑risk cSCC, integrating 40‑GEP results with BWH/AJCC8/NCCN staging improves metastatic risk stratification, supporting more risk‑aligned...
Clinical insightUse benzoyl peroxide and a topical retinoid (± topical antibiotic) as core therapy; add oral doxycycline when needed, and reserve isotretinoin for...
Clinical insightFor pemphigus, first-line rituximab (Ritux 3 regimen) achieved durable steroid-free control over 7 years with fewer relapses and SAEs than prednisone...
Clinical insightLong-term, higher cumulative TCS exposure correlates with greater odds of osteoporosis and MOF; minimize cumulative TCS dose when possible and...
Clinical insightOnce-daily topical PF-07038124 0.01% outperformed vehicle at 6 weeks in mild to moderate AD and plaque psoriasis. TEAEs were similar to vehicle (AD:...
Clinical insightPopulation-level data do not show increased risk of suicide or psychiatric disorders with isotretinoin, and suicide attempts were less likely 2–4...
Clinical insightIn dermatology RCTs, JAK inhibitors did not increase short-term risk of MACE, death, or VTE vs controls. Use routine cardiovascular/VTE risk...
Clinical insightGut microbiota profiles differ between controls and melanoma and between early- and late-stage disease, but specific taxonomic signals attenuate...
Clinical insightAmong toxin‑naive adults who achieve a ≥2‑grade forehead line response on on‑label onabotulinumtoxinA dosing, most report natural‑looking results and...
Clinical insightFor adolescents and adults with severe alopecia areata, oral JAK inhibitors provide meaningful regrowth for roughly 1 in 4 to 2 in 5 patients by...
Clinical insightVitiligo was associated with lower all-cause and multiple cause-specific mortality compared with matched controls in this large Korean cohort. This...
Clinical insightAbout one-quarter of SJS/TEN cases are antibiotic-associated worldwide, with sulfonamides leading and penicillins and cephalosporins next. When...
Clinical insightSystemic immune signatures in atopic dermatitis are age-specific beyond shared Th2 activation; consider patient age when interpreting blood...
Clinical insightIn middle‑aged to older adults, looking younger for one’s age correlates with fewer age‑related conditions and better cognition; facial ageing may be...
Clinical insightMost cutaneous reactions after CoronaVac or ZF2001 are mild, start within 3 days, and many resolve within 7–14 days with conventional therapy;...
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