Executive summary: American Academy of Dermatology guidelines of care for the management of atopic dermatitis in adults with topical therapies

Journal of the American Academy of Dermatology

Clinical Summary

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What was studied

Updated guidelines for managing atopic dermatitis in adults using topical therapies, based on a systematic review and GRADE methodology to assess evidence and make recommendations.

Key findings

Strong recommendations were made for nonprescription moisturizers, topical calcineurin inhibitors, topical corticosteroids, and topical PDE-4 and JAK inhibitors; conditional recommendations were made for bathing and wet wrap therapy and against topical antimicrobials, antiseptics, and antihistamines.

Clinical implications

For adult atopic dermatitis, prioritize moisturizers and guideline-supported topicals (corticosteroids, calcineurin inhibitors, PDE-4 and JAK inhibitors); consider bathing and wet wraps selectively, and avoid topical antimicrobials, antiseptics, and antihistamines.