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Golimumab in Treatment-Refractory Hidradenitis Suppurativa

JAMA Dermatology·June 10
DermatologyLimited evidenceHidradenitis SuppurativaCohort StudyTNF InhibitorAdultSimponiGolimumab

Summary

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What was studied

This cohort study evaluated the association between changes in IHS4 (International Hidradenitis Suppurativa Severity Score System) scores and treatment with intravenous or subcutaneous golimumab in patients with moderate to severe, treatment-refractory hidradenitis suppurativa.

Study limitations

Abstract-only data available; specific outcomes, sample size, follow-up duration, and comparator details are not reported.

Clinical implications

Golimumab (IV and SC) is being explored as an option for treatment-refractory moderate-to-severe HS; clinicians should await full study data before adopting this into routine practice.

Related Questions

Explore related topics

What biologics are effective for treatment-refractory hidradenitis suppurativa?How does golimumab compare to adalimumab for moderate to severe hidradenitis suppurativa?What is the IHS4 score and how is it used to measure hidradenitis suppurativa severity in clinical trials?

Publication Details

Year
2026
Journal
JAMA Dermatology
Source
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