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Mapping Clinical Diagnoses Associated With Neurodiversity and Neurodivergence in Mental Health Research
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Mapping Clinical Diagnoses Associated With Neurodiversity and Neurodivergence in Mental Health Research

JAMA Psychiatry·September 16
PsychiatryPractice changingAnxiety DisorderAttention-Deficit/Hyperactivity DisorderAutism Spectrum DisorderDyscalculiaDyslexiaDyspraxiaNeurodevelopmental DisordersScoping ReviewMixed

Summary

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What was studied

A scoping review mapped which clinical diagnoses are associated with the terms 'neurodivergent' and 'neurodiverse' in empirical mental health literature, searching four major databases up to August 1, 2025, and identifying 134 studies with 151,134 participants.

Key findings

Autism (68.7%) and ADHD (64.2%) were the most common diagnoses linked to these terms, but 29 studies (21.6%) specified no clinical diagnoses at all; participant identification relied on self-report (41.8%) or self-identification (37.3%), reflecting high heterogeneity.

Study limitations

Scoping reviews do not appraise study quality, so the heterogeneity identified may underestimate or overestimate true definitional inconsistency. Reliance on self-reported and self-identified diagnoses across included studies limits clinical precision.

Clinical implications

Clinicians and researchers should use specific diagnostic labels (e.g., autism, ADHD) rather than 'neurodivergent' when describing clinically defined populations. Reserve 'neurodivergent' for contexts centered on self-identification and lived experience.

Caveats

  • Level of evidence assigned as 3 (scoping review with no quality appraisal); some may classify this lower depending on hierarchy used.
  • 'Practice_changing' flag applied cautiously — the study challenges widespread terminology use in both clinical and research settings, which has direct implications for diagnostic coding and research design.
  • The sample size of 151,134 reflects participants across 134 included studies, not a single enrolled cohort — individual study sizes vary widely and are not reported separately.

Related Questions

Explore related topics

Which clinical diagnoses are most commonly included under the neurodivergent umbrella in research?How should clinicians document neurodivergent identity versus formal diagnosis in medical records?What are the methodological risks of using self-identification as a recruitment criterion in neurodevelopmental research?

Publication Details

Year
2026
Journal
JAMA Psychiatry
Sample Size
n=151,134
Source
View article
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