A case report examining mother-to-child transmission (MTCT) of hepatitis B virus (HBV) in an infant who received routine immunoprophylaxis (hepatitis B vaccine and HBIG), born to a mother with a high HBV viral load.
Despite standard immunoprophylaxis, MTCT of HBV occurred, highlighting that high maternal viral load can overcome routine preventive measures.
Single case report limits generalizability; specific maternal viral load threshold, antiviral treatment details, and immunoprophylaxis timing are not fully extractable from the abstract alone.
In pregnant patients with high HBV viral loads, routine infant immunoprophylaxis alone may not prevent MTCT; consider antiviral therapy (e.g., tenofovir) in the third trimester to reduce transmission risk.
Explore related topics
