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Evaluating the Impact of Stair Climbing on Cardiovascular Risk Reduction: A Systematic Review and Meta-analysis

American Journal of Cardiovascular Drugs·August 13
Cardiac & Cardiovascular SystemsConfirms priorAll-Cause MortalityCardiovascular DiseaseCardiovascular MortalitySystematic Review And Meta-AnalysisPhysical Activity InterventionMixed

Summary

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What was studied

This systematic review and meta-analysis evaluated the association between stair climbing and cardiovascular outcomes — including cardiovascular mortality, all-cause mortality, and cardiovascular disease incidence (MI, ischaemic stroke, heart failure) — across 9 observational studies with 480,479 patients identified from PubMed and Embase up to April 2025.

Key findings

Stair climbing was associated with a 39% reduction in cardiovascular mortality (RR 0.61, 95% CI 0.48–0.79, p = 0.0002) and a 24% reduction in all-cause mortality (RR 0.76, 95% CI 0.62–0.94, p = 0.01) in pooled analysis of 5 studies (n = 455,619).

Study limitations

- All included studies were observational (cohort design), so causality cannot be established. - Three studies rated only "Fair" quality on the Newcastle-Ottawa Scale, introducing residual confounding risk. - Only 9 studies met inclusion criteria; cardiovascular morbidity outcomes (MI, stroke, heart failure) were not pooled quantitatively.

Clinical implications

Encourage patients — especially sedentary ones — to incorporate stair climbing into daily routines at work and home, as even this modest activity is linked to meaningfully lower cardiovascular and all-cause mortality. No special equipment or gym access is required.

Caveats

  • All 9 included studies were observational (cohort design); no randomized controlled trials met inclusion criteria despite RCTs being listed as eligible — causality cannot be inferred.
  • Cardiovascular morbidity outcomes (MI, ischaemic stroke, heart failure) are mentioned as associated with stair climbing but no pooled effect sizes are reported in the abstract or results — quantitative data for morbidity are absent.
  • The cardiovascular mortality pooled analysis included only 5 of the 9 studies (n=455,619); the remaining 4 studies contributed to other outcomes but details are not provided in the available text.

Related Questions

Explore related topics

What is the minimum amount of stair climbing needed to reduce cardiovascular risk?How does stair climbing compare to other forms of moderate-intensity exercise for heart health?Are there cardiovascular benefits of stair climbing in patients with existing heart disease?

Publication Details

Year
2026
Journal
American Journal of Cardiovascular Drugs
Sample Size
n=480,479
Source
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