Updated AST IDCOP guidelines on vaccination (routine, travel, and live-attenuated vaccines) and non-pharmacological safe living strategies for solid organ transplant (SOT) candidates and recipients, incorporating evidence since the 2019 guidelines.
Key updates include: new vaccine recommendations for COVID-19 and RSV; newer formulations of pneumococcal, meningococcal, and hepatitis B vaccines; expanded age indications for recombinant zoster vaccine; and accumulating evidence supporting select live-attenuated vaccines in post-transplant pediatric and young adult patients under certain conditions.
Guideline document based on evidence review rather than a primary clinical trial; many recommendations may rely on observational or limited data given the immunocompromised population studied.
Review and update vaccination status in all SOT candidates before transplant and before any travel; for post-transplant patients, consider live-attenuated vaccines only in select pediatric and young adult cases, and counsel patients on food, water, pet, and sexual activity safety as part of routine care.
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