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Incidence and Outcomes of Emergency Physician-Performed Awake Intubations: A Report From the Airway Interventions Registry and Observational Database

Annals of Emergency Medicine·July 6Open Access
Emergency MedicineConfirms priorDifficult AirwayEmergency IntubationProspective Observational Registry StudyAwake Tracheal IntubationRapid Sequence IntubationAdult

Summary

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What was studied

This prospective registry study evaluated the incidence, practice patterns, and outcomes of emergency physician-performed awake tracheal intubations in a single academic, tertiary-care ED over 10 years (January 2015–January 2025), excluding sedation-only or dissociation-only intubations.

Key findings

Of 1,213 ED intubations screened, 87 (7.2%) were awake intubations; 92% (n=80; 95% CI 86–98%) succeeded without a major adverse event. First-pass success was 71% (n=62), RSI conversion occurred in 6.9% (n=6), and critical hypoxemia, hypotension, and cardiac arrest each occurred in ≤3% of cases.

Study limitations

Single-center academic ED limits generalizability. The 10-year sample yielded only 87 cases, limiting statistical power. No comparator group (e.g., RSI in similar high-risk patients) was included to contextualize outcomes.

Clinical implications

Emergency physicians can perform awake tracheal intubation with high success and low major adverse event rates in patients with anatomic or physiologic predictors of a difficult airway. Consider awake intubation as a viable ED strategy for high-risk airways, with RSI available as a backup in ~7% of cases.

Related Questions

Explore related topics

How does awake intubation compare to RSI in emergency patients with predicted difficult airways?What techniques and medications are used for awake tracheal intubation in the emergency department?What are the predictors of first-pass intubation failure in emergency department patients?

Publication Details

Year
2026
Journal
Annals of Emergency Medicine
Sample Size
n=87
Source
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