This systematic review evaluated thermal ablation modalities — cryoablation, microwave ablation (MWA), radiofrequency ablation (RFA), high-intensity focused ultrasound (HIFU), and laser ablation — as treatments for early-stage breast cancer, assessing efficacy and safety across available studies.
Specific pooled efficacy or safety numbers are not extractable from the provided metadata alone; however, the review synthesizes evidence across five ablation modalities for early-stage breast cancer to inform non-surgical treatment options.
As a systematic review based only on the available published literature, findings are limited by the heterogeneity of included studies, variation in tumor selection criteria across modalities, and likely absence of large randomized controlled trials for each technique.
Clinicians considering thermal ablation for early-stage breast cancer should weigh the specific modality's evidence base, as efficacy and safety profiles differ across cryoablation, MWA, RFA, HIFU, and laser ablation. This review provides a comparative framework to guide patient selection and shared decision-making.
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