The Hormone Cell Atlas mapped hormone production and sensitivity across 47 human tissues using a 14-million-cell single-cell dataset, characterizing which cells produce hormones and which cells respond to them.
The atlas identifies hormone-producing and hormone-receiving cells across 47 tissues at single-cell resolution, expanding known sites of hormone production and revealing previously uncharacterized receiver cell populations.
The abstract provides limited methodological detail; it is unclear whether the dataset integrates data from multiple donors or cohorts, and functional validation of newly identified hormone-cell relationships is not described.
This resource may reshape understanding of endocrine physiology and metabolism, offering a reference map for identifying novel therapeutic targets in hormonal and metabolic diseases.
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