This study assessed whether areas of delayed trans-septal conduction time (DCT) colocalize with critical ablation sites for intramural septal substrate ventricular tachycardia (ISS-VT) in 28 consecutive patients with non-ischemic cardiomyopathy (NICM), analyzing 56 distinct VTs.
Critical ISS-VT sites colocalized with DCT >100 ms; 94% (16/17) of VT termination sites had DCT >50% of the RV-paced QRS duration. Targeted ablation eliminated the targeted VT in 96% of cases and achieved non-inducibility of any VT in 79%.
Single-center consecutive series with a small sample (n=28); non-inducibility endpoint applied to unstable VTs without direct termination confirmation; no long-term follow-up outcomes reported.
In NICM patients with intramural septal VT, map for areas where DCT exceeds 50% of the RV-paced QRS duration — these zones are the most specific targets for septal substrate modification and correlated with VT termination in 94% of cases.
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