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Aortic Valve Replacement in Women of Reproductive Age

JACC·July 1
Cardiac & Cardiovascular SystemsPractice changingAortic Valve DiseasePregnancy With Prosthetic Heart ValveRegistry-Based Cohort StudyBioprosthetic ValveMechanical Heart ValveRoss ProcedureSurgical Valve ReplacementAdult

Summary

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What was studied

This brief report examines aortic valve replacement (AVR) options — mechanical, bioprosthetic, and the Ross procedure — in women of reproductive age, drawing on registry data (Swedish Cardiac Surgery Registry / SWEDEHEART) and current guideline recommendations.

Key findings

Full quantitative results are not available from the publisher page text; however, the study addresses the trade-offs between valve types in this population, including risks of anticoagulation with mechanical valves during pregnancy and structural valve deterioration with bioprosthetics.

Study limitations

Only the publisher page and reference list are accessible — full text, sample size, outcome data, and follow-up duration are not extractable. The Swedish registry setting may limit generalizability to other populations.

Clinical implications

When counseling women of reproductive age with aortic valve disease, weigh the teratogenic and thromboembolic risks of anticoagulation with mechanical valves against the higher reoperation risk of bioprosthetics; the Ross procedure is an increasingly guideline-supported alternative. A multidisciplinary team discussion — including cardiology, cardiac surgery, and obstetrics — is essential before any valve choice is made.

Related Questions

Explore related topics

What are the risks of mechanical vs bioprosthetic aortic valve replacement in women who want to get pregnant?Is the Ross procedure recommended for women of childbearing age with aortic valve disease?How should anticoagulation be managed during pregnancy in women with a mechanical heart valve?

Publication Details

Year
2026
Journal
JACC
Source
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