This expert consensus document from SCCT and SCAI (endorsed by ACC) evaluates the clinical use of fractional flow reserve derived from coronary computed tomography angiography (FFR-CT) — covering its technical basis, diagnostic performance, appropriate patient selection, and integration into clinical decision-making pathways.
The consensus provides evidence-based guidance on FFR-CT's role in the non-invasive physiologic assessment of coronary artery disease, supporting its use to guide revascularization decisions and reduce unnecessary invasive angiography — though specific aggregate outcome numbers are not extractable from the abstract/metadata alone.
As a consensus document rather than a primary research study, it reflects expert opinion and synthesis of existing evidence, which may be subject to guideline-committee bias. The evidence base it draws upon may not uniformly reflect all patient subgroups or real-world practice settings.
Clinicians can use FFR-CT as a non-invasive physiologic tool to assess the hemodynamic significance of coronary lesions before pursuing invasive angiography. This consensus offers a framework for appropriate patient selection and integration of FFR-CT into stable chest pain workup pathways.
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