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Beyond vaccines: closing the critical gap in diagnostics and therapeutics for outbreak response

The Lancet Infectious Diseases·July 17
Infectious DiseasesPractice changingInfectious Disease OutbreaksCommentaryDiagnosticsTherapeuticsVaccines

Summary

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What was studied

This commentary or analysis examines the gap in outbreak response preparedness beyond vaccines, focusing on the underdevelopment of diagnostics and therapeutics for epidemic and pandemic-prone pathogens.

Key findings

The paper argues that diagnostics and therapeutics remain critically underfunded and underdeveloped relative to vaccines in outbreak response frameworks, leaving a dangerous gap in global health security.

Study limitations

As a commentary or perspective piece, this paper does not present primary clinical trial data or patient-level outcomes, limiting direct evidence-based conclusions.

Clinical implications

Clinicians and health systems should advocate for greater investment in point-of-care diagnostics and pathogen-specific therapeutics alongside vaccine development for outbreak preparedness. Relying on vaccines alone leaves patients vulnerable during the critical early phase of an outbreak.

Related Questions

Explore related topics

What are the biggest gaps in diagnostics and therapeutics for emerging infectious disease outbreaks?How does investment in outbreak therapeutics compare to vaccine development globally?What point-of-care diagnostic tools are available for epidemic-prone pathogens?

Publication Details

Year
2026
Journal
The Lancet Infectious Diseases
Source
View article
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