adult: Research & Clinical Takeaways

Stent‑based photobiomodulation was feasible, well tolerated, and associated with a low rate of severe mucositis in this small cohort. Continue using...

Short-course taVNS improved clinician-rated erythema and mood symptoms versus sham in ETR with few adverse events; clinicians may discuss this...

Delivery-room teams report low confidence in identifying and explaining congenital skin lesions and strongly want training. Establish targeted...

In darker phototypes with refractory melasma, a single 755‑nm picosecond alexandrite laser session followed by topical JAK inhibition and...

At 6 months, dutasteride 0.5 mg daily ranks highest for increasing hair density, with finasteride (oral/topical) and topical minoxidil also...

When selecting retinol products for sensitive skin, co‑formulations with 2% PLG, 5% ceramides, 3% acetyl glucosamine, 2% panthenol, 0.2% TECA, or...

As an adjunct to standard topicals after inadequate response, monthly HMWNCHA+SA mesotherapy improved erythema, hydration, elasticity, and symptoms...

In women with epidermal melasma, a niacinamide/2‑mercaptonicotinyl glycine dermocosmetic achieved similar 6‑month MASI reductions to Kligman triple...

Refer high‑risk MF/SS early; aim for CR or deep response (VGPR or mSWAT <10) before RIC allo‑HCT, prefer MRD/MUD donors, and observe a 6‑week washout...

For adults who cannot take oral antifungals, an 8‑session diode laser plus red‑laser PDT protocol achieved higher clinical cure and faster healing...

When multiple soft, flesh‑colored papules or nodules cluster within one dermatome, consider segmental neurofibromatosis; biopsy showing S100‑positive...

Combining BV with RTx (sequentially or concurrently) was feasible and generally well tolerated, with expected toxicities and no new safety signals....

XP-A due to c.389G>A (p.R130K) can present with mild cutaneous disease yet later neurologic decline; functional testing can reveal marked NER defects...

A diagnostic vignette of a woman in her 30s with a 1-year history of painful annular eruptions on the anterior neck that began as erythematous...

For adults with mild to moderate psoriasis on stable topical therapy, a 16-week, dietitian-guided Mediterranean diet produced clinically meaningful...

In adults with severe alopecia areata, baricitinib 4 mg daily led to SALT ≤20 in 63% by 48 weeks, with adverse events in 9.4%. Real-world results...

In vasculitic-appearing eruptions, consider monoclonal cryoglobulinemia and assess for an underlying B‑cell lymphoproliferative disorder when...

Docetaxel can trigger localized, unilateral scleroderma without Raynaud’s or nailfold changes; consider biopsy to confirm when new, limb-limited...

Routine high-SPF sunscreen use over a year led to lower 25(OH)D and more deficiency than discretionary use; regular sunscreen users may need vitamin...

For adults seeking noninvasive midsection fat reduction, dual‑applicator cryolipolysis achieved high satisfaction at 12 weeks, with device‑related...

For adults with plaque psoriasis who fail a biologic, switching—especially across classes—can yield high PASI responses without an observed increase...

Track flare burden. More frequent, longer, and more severe flares align with worse quality of life and predict more severe AD the next year,...

In psoriasis without musculoskeletal symptoms, subclinical synovitis is more prevalent than in healthy controls; MRI may detect it more often than...

Several agents improved HiSCR-50 by 12–16 weeks vs placebo in adults with moderate to severe HS, with low SAE rates across groups; weekly adalimumab...

For adults with atopic dermatitis, anticipate higher visit burden during temperature extremes and when PM10 and SO2 are elevated; reducing exposure...

Dupilumab was associated with a higher relative risk of new-onset psoriasis vs other systemic agents in adults with AD, but the absolute excess risk...

Once-daily roflumilast foam 0.3% outperformed vehicle for scalp and limited body psoriasis over 8 weeks and reduced itch early, with low adverse...

For H1-antihistamine–refractory CSU, rilzabrutinib 1200 mg/d reduced itch and hive activity over 12 weeks vs placebo with early onset and mainly...

A retrospective cohort study of US adults examined the relationship between acne and eating disorders, with participant data available through the...

In high‑risk patients, adding 3D‑TBP and SDDI via teledermatology increased excisions/biopsies and keratinocyte cancer detection but did not produce...

Prevalence and co-occurrence of eczema types in U.S. adults using data from the All of Us Research Program.

In adults with moderate to severe papulopustular rosacea, 16 weeks of DFD-29 40 mg daily outperformed doxycycline 40 mg and placebo on IGA success...

For patients already on PD‑1/PD‑L1 therapy, AK burden and KC excisions may decline over 12 months. Do not start ICIs solely for field cancerization...

An AI-enabled wearable with haptic feedback reduced nocturnal scratching over one week in adults with mild atopic dermatitis without shortening...

Patients who self-identify TSW report substantial morbidity (itch, sleep loss, mood symptoms) and often believe steroids trigger it; clinicians...

For adults with atopic dermatitis, a brief self-guided online CBT program was noninferior to clinician-guided CBT on POEM and required minimal...

Thin melanomas 0.8–1.0 mm carry markedly higher melanoma-specific mortality than <0.8 mm, supporting a 0.8‑mm threshold to guide care and counseling....

Patients with CLE appear to have increased ASCVD risk; consider cardiovascular risk screening similar to other higher-risk groups.

Nemolizumab every 4 weeks improved itch and skin clearance by week 16 vs placebo in adults with moderate to severe prurigo nodularis, with mostly...

When topical minoxidil is ineffective, impractical, or irritant, experts support considering LDOM in adults and adolescents, typically starting at...