2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:T716,Microfocused ultrasound with visualization (MFU-V) is well established for noninvasive lifting of the face, neck, and décolleté. U.S. FDA clearance was recently granted for treatment of the abdomen and upper arms, supported by favorable safety data and emerging evidence of efficacy of its use to address skin and soft tissue laxity in body regions. Guidance on best practices for these additional indications is desirable. This consensus aims to provide evidence-based and practice-informed recommendations supporting safe, effective, and reproducible MFU-V treatments for the additional body indications. An international, multidisciplinary panel of aesthetic experts developed consensus recommendations for MFU-V treatment of additional body areas based on clinical evidence, expert experience, and structured virtual discussions. This global expert consensus affirms MFU-V as a safe and effective noninvasive modality for treating mild to moderate skin and soft tissue laxity in the abdomen and upper arms. Three key domains were identified as critical to optimizing outcomes: patient selection, treatment planning, and expectation management. Ideal candidates are those with mild to moderate laxity and target tissues located at treatable depths. Real-time ultrasound imaging was emphasized for accurate targeting, anatomical safety, and treatment precision. The panel developed practical treatment protocols for the abdomen and upper arms, including recommended treatment zones, line densities, and transducer depths tailored to tissue characteristics. Safe and effective MFU-V outcomes rely on real-time ultrasound visualization, thoughtful patient selection, expectation management, and anatomically guided treatment. Continued research is needed to refine protocols and guide emerging body applications.31:T8a6,ABSTRACTBackgroundMicrofocused ultrasound with visualization (MFU‐V) is well established for noninvasive lifting of the face, neck, and décolleté. U.S. FDA clearance was recently granted for treatment of the abdomen and upper arms, supported by favorable safety data and emerging evidence of efficacy of its use to address skin and soft tissue laxity in body regions. Guidance on best practices for these additional indications is desirable.AimsThis consensus aims to provide evidence‐based and practice‐informed recommendations supporting safe, effective, and reproducible MFU‐V treatments for the additional body indications.MethodsAn international, multidisciplinary panel of aesthetic experts developed consensus recommendations for MFU‐V treatment of additional body areas based on clinical evidence, expert experience, and structured virtual discussions.ResultsThis global expert consensus affirms MFU‐V as a safe and effective noninvasive modality for treating mild to moderate skin and soft tissue laxity in the abdomen and upper arms. Three key domains were identified as critical to optimizing outcomes: patient selection, treatment planning, and expectation management. Ideal candidates are those with mild to moderate laxity and target tissues located at treatable depths. Real‐time ultrasound imaging was emphasized for accurate targeting, anatomical safety, and treatment precision. The panel developed practical treatment protocols for the abdomen and upper arms, including recommended treatment zones, line densities, and transducer depths tailored to tissue characteristics.ConclusionSafe and effective MFU‐V outcomes rely on real‐time ultrasound visualization, thoughtful patient selection, expectation management, and anatomically guided treatment. Continued research is needed to refine protocols and guide emerging body applications.25:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Abdominal Skin Laxity: condition Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Abdominal Skin Laxity (condition). Clinician-written summaries and actionable practice insights. Updated daily.\",\"url\":\"https://www.reachrx.ai/hub/tag/condition/Abdominal%20Skin%20Laxity\",\"breadcrumb\":{\"@type\":\"BreadcrumbList\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https://www.reachrx.ai\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research Hub\",\"item\":\"https://www.reachrx.ai/hub\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Conditions\",\"item\":\"https://www.reachrx.ai/hub/tag/condition\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Abdominal Skin Laxity\",\"item\":\"https://www.reachrx.ai/hub/tag/condition/Abdominal%20Skin%20Laxity\"}]}}"}}]],["$","$L2f",null,{"title":"Abdominal Skin Laxity: Research & Clinical Takeaways","description":"Discover peer-reviewed research on Abdominal Skin Laxity with concise clinician summaries and next-step guidance.","papers":[{"doi":"10.1111/jocd.70449","pmid":"40995829","title":"Microfocused Ultrasound With Visualization for Body Indications: A Global Expert Consensus on Best Practices for Treatment of the Abdomen and Arms","journal_title":"Journal of Cosmetic Dermatology","journal_issn":"1473-2130","published_at":"2025-09-25T00:00:00.000Z","url":"https://doi.org/10.1111/jocd.70449","source_score":1,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2025-10-01","doi":"10.1111/jocd.70449","days":"7","issn":"1473-2130","rank":"9","field":"Clinical Medicine","score":"1","category":"Dermatology","categories":["Dermatology"],"_categories":["Dermatology"]},"pubmed":{"doi":"10.1111/jocd.70449","title":"Microfocused Ultrasound With Visualization for Body Indications: A Global Expert Consensus on Best Practices for Treatment of the Abdomen and Arms.","journal":"Journal of cosmetic dermatology","methods":"","results":"This global expert consensus affirms MFU-V as a safe and effective noninvasive modality for treating mild to moderate skin and soft tissue laxity in the abdomen and upper arms. Three key domains were identified as critical to optimizing outcomes: patient selection, treatment planning, and expectation management. Ideal candidates are those with mild to moderate laxity and target tissues located at treatable depths. Real-time ultrasound imaging was emphasized for accurate targeting, anatomical safety, and treatment precision. The panel developed practical treatment protocols for the abdomen and upper arms, including recommended treatment zones, line densities, and transducer depths tailored to tissue characteristics.","abstract":"$30","keywords":["MFU‐V","body contouring","consensus","energy‐based device","real‐time visualization","real‐world evidence","skin laxity"],"pubmed_id":"40995829","conclusions":"Safe and effective MFU-V outcomes rely on real-time ultrasound visualization, thoughtful patient selection, expectation management, and anatomically guided treatment. Continued research is needed to refine protocols and guide emerging body applications.","publication_date":"2025-09-25T00:00:00"},"crossref":{"DOI":"10.1111/jocd.70449","URL":"https://doi.org/10.1111/jocd.70449","ISSN":["1473-2130","1473-2165"],"link":[{"URL":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/jocd.70449","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":null,"type":"journal-article","issue":"10","score":1,"title":["Microfocused Ultrasound With Visualization for Body Indications: A Global Expert Consensus on Best Practices for Treatment of the Abdomen and Arms"],"author":[{"given":"Frank","family":"Lin","sequence":"first","affiliation":[{"name":"Monash University Clayton Victoria Australia"}]},{"given":"Vasanop","family":"Vachiramon","sequence":"additional","affiliation":[{"name":"Division of Dermatology Faculty of Medicine Ramathibodi Hospital, Mahidol University Bangkok Thailand"}]},{"given":"Gabriela","family":"Casabona","sequence":"additional","affiliation":[{"name":"Ocean Clinic Marbella Málaga Spain"}]},{"given":"Jessie","family":"Cheung","sequence":"additional","affiliation":[{"name":"Cheung Aesthetics & Wellness Willowbrook Illinois USA"}]},{"given":"Ana Lúcia Gonzaga","family":"da Cunha","sequence":"additional","affiliation":[{"name":"Albert Einstein Teaching and Research Center São Paulo Brazil"}]},{"given":"Tatjana","family":"Pavicic","sequence":"additional","affiliation":[{"name":"Private Practice for Dermatology & Aesthetics Dr. Tatjana Pavicic Munich Germany"}]},{"given":"Julieta","family":"Spada","sequence":"additional","affiliation":[{"name":"Spada Dermatology & Aesthetics Buenos Aires Argentina"}]},{"given":"Sabrina","family":"Fabi","sequence":"additional","affiliation":[{"name":"University of California San Diego California USA"}]}],"issued":{"date-parts":[[2025,9,25]]},"member":"311","prefix":"10.1111","source":"Crossref","volume":"24","archive":["Portico"],"created":{"date-time":"2025-09-25T10:30:57Z","timestamp":1758796257000,"date-parts":[[2025,9,25]]},"indexed":{"date-time":"2025-09-26T00:15:23Z","timestamp":1758845723744,"date-parts":[[2025,9,26]]},"license":[{"URL":"http://creativecommons.org/licenses/by/4.0/","start":{"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000,"date-parts":[[2025,9,25]]},"delay-in-days":0,"content-version":"vor"}],"subject":[],"abstract":"$31","language":"en","relation":{},"resource":{"primary":{"URL":"https://onlinelibrary.wiley.com/doi/10.1111/jocd.70449"}},"subtitle":[],"assertion":[{"name":"received","group":{"name":"publication_history","label":"Publication History"},"label":"Received","order":0,"value":"2025-06-16"},{"name":"accepted","group":{"name":"publication_history","label":"Publication History"},"label":"Accepted","order":2,"value":"2025-09-09"},{"name":"published","group":{"name":"publication_history","label":"Publication History"},"label":"Published","order":3,"value":"2025-09-25"}],"deposited":{"date-time":"2025-09-25T10:31:00Z","timestamp":1758796260000,"date-parts":[[2025,9,25]]},"issn-type":[{"type":"print","value":"1473-2130"},{"type":"electronic","value":"1473-2165"}],"published":{"date-parts":[[2025,9,25]]},"publisher":"Wiley","reference":[{"DOI":null,"key":"e_1_2_10_2_1","year":"2019","issue":"5","author":"Fabi S. G.","volume":"18","first-page":"426","unstructured":null,"article-title":"Optimizing Patient Outcomes by Customizing Treatment With Microfocused Ultrasound With Visualization: Gold Standard Consensus Guidelines From an Expert Panel","journal-title":"Journal of Drugs in Dermatology","doi-asserted-by":null},{"DOI":null,"key":"e_1_2_10_3_1","year":"2021","issue":"5","author":"Park J. Y.","volume":"14","first-page":"E70","unstructured":null,"article-title":"Customized Treatment Using Microfocused Ultrasound With Visualization for Optimized Patient Outcomes: A Review of Skin‐Tightening Energy Technologies and a Pan‐Asian Adaptation of the Expert Panel's Gold Standard Consensus","journal-title":"Journal of Clinical and Aesthetic Dermatology","doi-asserted-by":null},{"DOI":null,"key":"e_1_2_10_4_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":"Ulthera Inc. “US Instructions for Use for Ultherapy PRIME” 2025 https://ultherapy.com/app/themes/ultherapy2020/pdfs/1015390IFU‐Rev‐02‐US‐PRIME‐IFU.pdf.","article-title":null,"journal-title":null,"doi-asserted-by":null},{"DOI":"10.1097/dss.0000000000000233","key":"e_1_2_10_5_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1093/asj/sjae228","key":"e_1_2_10_6_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1111/jocd.14666","key":"e_1_2_10_7_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":null,"key":"e_1_2_10_8_1","year":"2016","issue":"2","author":"Werschler W. P.","volume":"9","first-page":"27","unstructured":null,"article-title":"Long‐Term Efficacy of Micro‐Focused Ultrasound With Visualization for Lifting and Tightening Lax Facial and Neck Skin Using a Customized Vectoring Treatment Method","journal-title":"Journal of Clinical and Aesthetic Dermatology","doi-asserted-by":null},{"DOI":"10.1016/j.jaad.2013.06.045","key":"e_1_2_10_9_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1111/jocd.16658","key":"e_1_2_10_10_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1097/dss.0000000000002576","key":"e_1_2_10_11_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1002/lsm.23234","key":"e_1_2_10_12_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.4236/jcdsa.2012.222022","key":"e_1_2_10_13_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1097/dss.0000000000000390","key":"e_1_2_10_14_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1002/lsm.23307","key":"e_1_2_10_15_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1111/j.1524‐4725.2012.02338.x","key":"e_1_2_10_16_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":null,"key":"e_1_2_10_17_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":"K.Darji “Parallel Ultrasound Beams Versus Microfocused Ultrasound for the Treatment of Upper Inner Arm Skin Laxity ”Conference Abstract and Presentation Presented at: ASLMS 2024 Conference Abstract and Presentation; 12 April 2024 2024; Baltimore MD USA.","article-title":null,"journal-title":null,"doi-asserted-by":null},{"DOI":"10.1097/dss.0000000000003003","key":"e_1_2_10_18_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1093/asj/sjx218","key":"e_1_2_10_19_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1007/bf01570212","key":"e_1_2_10_20_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1177/1090820x12461498","key":"e_1_2_10_21_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.3109/14764172.2014.949273","key":"e_1_2_10_22_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1097/dss.0000000000000126","key":"e_1_2_10_23_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":null,"key":"e_1_2_10_24_1","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":"Ulthera Inc. “ULTHERA SYSTEM: Instruções de Uso – Apresentação da tecnologia DeepSEE para Ultherapy PRIME ” 2024 https://merzaesthetics.com.br/app/uploads/2025/02/Ulthera‐Prime_1015407IFU‐Rev‐00_pt.pdf.","article-title":null,"journal-title":null,"doi-asserted-by":null}],"short-title":[],"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"update-policy":"https://doi.org/10.1002/crossmark_policy","alternative-id":["10.1111/jocd.70449"],"article-number":"e70449","content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"original-title":[],"container-title":["Journal of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,10]]},"reference-count":23,"published-online":{"date-time":null,"timestamp":null,"date-parts":[[2025,9,25]]},"references-count":23,"short-container-title":["J of Cosmetic Dermatology"],"is-referenced-by-count":0},"unpaywall":{"doi":"10.1111/jocd.70449","is_oa":true,"title":"Microfocused Ultrasound With Visualization for Body Indications: A Global Expert Consensus on Best Practices for Treatment of the Abdomen and Arms","updated":"2025-09-27T02:44:13+00:00","published_date":"2025-09-25","best_oa_location":{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jocd.70449","pmh_id":null,"url_for_pdf":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jocd.70449","url_for_landing_page":"https://doi.org/10.1111/jocd.70449"}}},"created_at":"2025-10-03T07:07:01.912Z","updated_at":"2025-10-06T07:08:34.463Z","tags":[{"paper_doi":"10.1111/jocd.70449","tag_type":"brand","value":"Ultherapy","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"brand","value":"Ultherapy Prime","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"category","value":"Dermatology","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"condition","value":"Abdominal Skin Laxity","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"condition","value":"Upper Arm Skin Laxity","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"impact_flag","value":"limited_evidence","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"level_of_evidence","value":"7","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"modality","value":"Microfocused Ultrasound With Visualization","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"study_design","value":"Guideline","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"warning","value":"Design classified as a guideline based on expert consensus, not an interventional study.","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"warning","value":"Evidence cited consists of small, mostly prospective studies with short follow‑up; durability beyond ~6 months is uncertain.","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"warning","value":"Industry funding and author financial relationships with the device manufacturer may introduce bias.","value_numeric":null}],"summaries":{"what_studied":"An international, multidisciplinary panel developed consensus recommendations for using microfocused ultrasound with visualization (MFU‑V; Ultherapy/Ultherapy PRIME) to treat mild to moderate skin and soft tissue laxity of the abdomen and upper arms, based on published clinical evidence, expert experience, and structured virtual discussions.","key_result":"The panel affirmed MFU‑V as a safe, effective noninvasive option, citing three abdominal studies (n=54) and five upper‑arm studies (n=113) showing clinician‑ and patient‑reported improvements with no serious or unexpected adverse events, with effects often sustained for 6 months or longer after maximal improvement.","limitations":"Recommendations derive from expert consensus and small prospective studies; large, comparative trials and longer follow‑up are lacking. The work was funded by Merz Aesthetics, and all panelists reported financial relationships with the device manufacturer.","practice_takeaway":"Use real‑time ultrasound to individualize depth and density: abdomen typically treated with a 12‑column (2×4 cm) grid delivering a median 720 lines using dual‑depth (4.5 and 3.0 mm) with optional 1.5 mm for crepiness, avoiding the umbilicus. For upper arms, treat only the middle third with a 6‑column grid per region and a median 240 lines, using 1.5/3.0 mm anteriorly and 3.0/4.5 mm posteriorly, with caution near neurovascular structures and in low‑BMI or post‑weight‑loss patients."}}],"initialOffset":1,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"condition","value":"Abdominal Skin Laxity"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Conditions","href":"/hub/tag/condition"},{"name":"Abdominal Skin Laxity"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"condition","hub_tag_value":"Abdominal Skin Laxity"}}}]]

Papers