2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:T40f,270 women were included in the final analysis (intervention n=132, usual care n=138; mean age 34, 60.4% from a self-reported non-Caucasian ethnic group). There was no difference in the primary outcome [hazard ratio (HR) 1.0, 95%CI 0.57-1.76; p=0.99]. There was also no difference in secondary fetal and maternal outcomes. The intervention group had fewer total antenatal attendances (median [inter-quartile range (IQR)]: 14 [10-17]) compared to usual care (16 [13-20]; p< 0.01), as well as fewer planned outpatient appointments (median [IQR]: 10 [8-12] vs. 13 [10-16]; p<0.01), without an associated increase in unscheduled hospital presentations. Women undertaking remote blood pressure monitoring were less likely to be admitted to hospital for any cause [HR 0.54, 95% confidence interval (CI) 0.30-0.97; p=0.04], as well as specifically for hypertension [HR 0.41, 95%CI 0.19-0.88, p=0.02]. More antihypertensive prescriptions filled per patient in the intervention arm compared to usual care (median [IQR]: 5 [3-9] vs. 3 [2-5]; p<0.01).31:Tc90,Women at high risk for developing preeclampsia are recommended to have additional blood pressure surveillance, but frequent outpatient attendances are demanding for patients and the healthcare system. It is unclear whether remote blood pressure monitoring can replace conventional office-based monitoring and improve healthcare utilisation without increasing the signal for harm. To evaluate the effects of substituting clinic blood pressure monitoring with remote blood pressure monitoring on fetal and maternal outcomes, and healthcare utilisation, in pregnant women at high risk of developing preeclampsia. Unblinded, non-inferiority, multicentre randomized controlled trial, with recruitment between July 2022 and February 2024 from 3 metropolitan hospitals in Australia. Participants were pregnant women at high-risk of developing preeclampsia based on clinical risk factors or combined first trimester screening tests, who are routinely referred to a specialist hypertension service for extra blood pressure surveillance, in addition to standard antenatal care. Women randomised to usual care attended these specialist hypertension clinics in-person, with frequency of appointments dictated by clinical need. Women randomised to remote blood pressure monitoring, in addition to receiving routine antenatal care, measured their own blood pressure using an automated blood pressure machine with data transmitted via a smartphone application for specialist review. The primary outcome was a perinatal composite of adverse events of at least one of perinatal loss, high-level neonatal care for over 48 hours or a small-for-gestational age baby (<10th centile for fetal weight). The primary outcome was assessed in the intention-to-treat population. The trial was prospectively registered with the Australian and New Zealand Clinical Trials Registry (ACTRN12620001049965p). 270 women were included in the final analysis (intervention n=132, usual care n=138; mean age 34, 60.4% from a self-reported non-Caucasian ethnic group). There was no difference in the primary outcome [hazard ratio (HR) 1.0, 95%CI 0.57-1.76; p=0.99]. There was also no difference in secondary fetal and maternal outcomes. The intervention group had fewer total antenatal attendances (median [inter-quartile range (IQR)]: 14 [10-17]) compared to usual care (16 [13-20]; p< 0.01), as well as fewer planned outpatient appointments (median [IQR]: 10 [8-12] vs. 13 [10-16]; p<0.01), without an associated increase in unscheduled hospital presentations. Women undertaking remote blood pressure monitoring were less likely to be admitted to hospital for any cause [HR 0.54, 95% confidence interval (CI) 0.30-0.97; p=0.04], as well as specifically for hypertension [HR 0.41, 95%CI 0.19-0.88, p=0.02]. More antihypertensive prescriptions filled per patient in the intervention arm compared to usual care (median [IQR]: 5 [3-9] vs. 3 [2-5]; p<0.01). Compared to usual care, remote blood pressure monitoring reduced antenatal outpatient appointments and the likelihood of inpatient admissions, without increasing adverse fetal and maternal outcomes. Women undertaking remote monitoring were also more likely to fill antihypertensive medication scripts.32:T7a7,Individuals who experience hypertensive disorders of pregnancy (HDPs) are at increased risk for downstream pregnancy-related complications, yet the variability in this risk among Asian American, Native Hawaiian, and Pacific Islander individuals remains understudied. This study investigated the risk for 5 HDP outcomes-chronic hypertension, chronic hypertension with superimposed preeclampsia, gestational hypertension, preeclampsia, and severe preeclampsia or eclampsia-among 15 disaggregated Asian American, Native Hawaiian, and Pacific Islander subgroups and assessed maternal characteristics that may be driving differences. We used infant and fetal vital records linked to maternal hospital discharge records from births to Asian American, Native Hawaiian, and Pacific Islander individuals in California from 2007 to 2019. Modified Poisson regression models estimated risk ratios (RR) for each outcome with sequential adjustments to assess the contributions of maternal sociodemographic and health-related characteristics to variability in risk. The largest subgroup-Chinese individuals-was the reference group. The cohort included 772 688 individuals. Prevalence of HDPs ranged from 3.7% among Chinese individuals (n=7930) to 13.0% among Guamanian individuals (n=247). All Pacific Islander subgroups and Filipino individuals were consistently at higher risk for HDPs than Chinese individuals, whereas Korean, Vietnamese, and Japanese individuals tended to be at lowest risk. After full adjustment, the highest risk groups had adjusted relative risks 2- to 3-fold higher than Chinese individuals. The variability in HDP risk observed across Asian American, Native Hawaiian, and Pacific Islander populations further demonstrates the need to study health outcomes in disaggregated subgroups. These findings may help providers identify individuals at high risk for HDPs, enabling prevention, prompt treatment, and reduced adverse maternal health outcomes.33:Ta70, Background Individuals who experience hypertensive disorders of pregnancy (HDPs) are at increased risk for downstream pregnancy‐related complications, yet the variability in this risk among Asian American, Native Hawaiian, and Pacific Islander individuals remains understudied. This study investigated the risk for 5 HDP outcomes—chronic hypertension, chronic hypertension with superimposed preeclampsia, gestational hypertension, preeclampsia, and severe preeclampsia or eclampsia—among 15 disaggregated Asian American, Native Hawaiian, and Pacific Islander subgroups and assessed maternal characteristics that may be driving differences. Methods We used infant and fetal vital records linked to maternal hospital discharge records from births to Asian American, Native Hawaiian, and Pacific Islander individuals in California from 2007 to 2019. Modified Poisson regression models estimated risk ratios (RR) for each outcome with sequential adjustments to assess the contributions of maternal sociodemographic and health‐related characteristics to variability in risk. The largest subgroup—Chinese individuals—was the reference group. Results The cohort included 772 688 individuals. Prevalence of HDPs ranged from 3.7% among Chinese individuals (n=7930) to 13.0% among Guamanian individuals (n=247). All Pacific Islander subgroups and Filipino individuals were consistently at higher risk for HDPs than Chinese individuals, whereas Korean, Vietnamese, and Japanese individuals tended to be at lowest risk. After full adjustment, the highest risk groups had adjusted relative risks 2‐ to 3‐fold higher than Chinese individuals. Conclusions The variability in HDP risk observed across Asian American, Native Hawaiian, and Pacific Islander populations further demonstrates the need to study health outcomes in disaggregated subgroups. These findings may help providers identify individuals at high risk for HDPs, enabling prevention, prompt treatment, and reduced adverse maternal health outcomes. 25:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Hypertensive Disorders of Pregnancy: condition Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Hypertensive Disorders of Pregnancy (condition). Clinician-written summaries and actionable practice insights. 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Diagnostic criteria are unchanged (2 of 3: irregular cycles/ovulatory dysfunction, clinical or biochemical hyperandrogenism, elevated AMH or polyfollicular ovarian morphology on ultrasound).","limitations":"This is a narrative special report, not a systematic review or meta-analysis; no new primary data are presented. Evidence grading of cited studies is not formally assessed. Recommendations reflect expert consensus rather than randomized trial evidence.","practice_takeaway":"At the first obstetric visit, document PMOS as an active risk modifier and integrate it into antenatal decision-support pathways for gestational diabetes, hypertensive disorders, and preterm birth monitoring. Routinely screen and counsel patients with PMOS for psychological, metabolic, and cardiometabolic risks from adolescence through menopause."}},{"doi":"10.1097/aog.0000000000006410","pmid":"42659593","title":"Pregnancy Outcomes in Individuals With Long COVID","journal_title":"Obstetrics & Gynecology","journal_issn":"0029-7844","published_at":"2026-08-27T00:00:00.000Z","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13523009/","source_score":19,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-09-02T06:22:35.878Z","updated_at":"2026-09-02T06:22:35.878Z","tags":[{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"condition","value":"Long COVID","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"condition","value":"Preterm Birth","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"impact_flag","value":"safety_signal","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"level_of_evidence","value":"2","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"sample_size","value":"n=603","value_numeric":603},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"study_design","value":"Prospective Cohort Study","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"warning","value":"Long COVID classification was based on a symptom index score (LCRI ≥11) rather than a clinical diagnosis, which may introduce misclassification.","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"warning","value":"No uninfected control group was included; all comparisons are between Long COVID-likely and Long COVID-indeterminate participants, both of whom had prior SARS-CoV-2 infection.","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006410","tag_type":"warning","value":"The hypertensive disorders of pregnancy association was found only in the sensitivity analysis (average treatment effect among the treated), not the pre-specified primary analysis — this limits the strength of that finding and should be interpreted cautiously.","value_numeric":null}],"summaries":{"what_studied":"This multicenter prospective cohort study (RECOVER-Adult) evaluated whether a maternal Long COVID classification (LCRI score ≥11) was associated with adverse pregnancy outcomes in 603 SARS-CoV-2-infected participants enrolled October 2021–January 2024, comparing likely Long COVID vs. Long COVID-indeterminate groups.","key_result":"Likely Long COVID was not associated with preterm birth in the primary analysis (adjusted rate 8.1% vs. 9.6%, ARR 0.82, 95% CI 0.36–1.90). In a sensitivity analysis, it was associated with increased hypertensive disorders of pregnancy (39.0% vs. 25.9%, ARR 1.51, 95% CI 1.12–2.03), but not with cesarean delivery, NICU admission, or small-for-gestational-age birth.","limitations":"The hypertensive disorders signal emerged only in a sensitivity analysis (average treatment effect among the treated), not the primary analysis, limiting causal inference. The study lacked a SARS-CoV-2-uninfected comparator group, and the Long COVID classification relied on symptom surveys that may not capture all cases accurately.","practice_takeaway":"Pregnant patients with a Long COVID classification do not appear to face a significantly higher risk of preterm birth, but a potential signal for hypertensive disorders of pregnancy warrants closer blood pressure monitoring. Screen Long COVID patients for adverse social determinants of health, as this group showed higher rates of food insecurity, financial hardship, and medical discrimination."}},{"doi":"10.1097/aog.0000000000006398","pmid":"42623674","title":"Risk of Recurrent Severe Preeclampsia, HELLP (Hemolysis, Elevated Liver Enzymes, and Low Platelet Count) Syndrome, and Eclampsia in a Subsequent Pregnancy","journal_title":"Obstetrics & Gynecology","journal_issn":"0029-7844","published_at":"2026-08-20T00:00:00.000Z","url":"https://doi.org/10.1097/aog.0000000000006398","source_score":7,"is_retracted":false,"is_open_access":false,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-09-04T06:22:18.980Z","updated_at":"2026-09-04T06:22:18.980Z","tags":[{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"condition","value":"Eclampsia","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"condition","value":"HELLP Syndrome","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"condition","value":"Preeclampsia","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"impact_flag","value":"confirms_prior","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"level_of_evidence","value":"3","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"sample_size","value":"n=560295","value_numeric":560295},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"study_design","value":"Retrospective Cohort Study","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"warning","value":"ICD-10 code–based classification of HELLP syndrome and eclampsia subtypes may lead to diagnostic misclassification; clinical severity gradations within 'severe features' are not distinguishable.","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"warning","value":"No modality, brand, or generic drug tags were applied as the study is observational and does not evaluate a specific treatment intervention.","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006398","tag_type":"warning","value":"The study captures only patients with two or more pregnancies observed within the same hospital system database, which may underrepresent patients who delivered at different institutions or had pregnancy losses not captured in the Premier database.","value_numeric":null}],"summaries":{"what_studied":"This retrospective cohort study used the Premier Inpatient database (Oct 2015–Dec 2020) to estimate recurrence risk of severe hypertensive disorders of pregnancy (HDP)—including preeclampsia with severe features, HELLP syndrome, and eclampsia—in a subsequent pregnancy among 560,295 U.S. patients with two or more observed deliveries.","key_result":"Overall recurrence of severe HDP was 14.9% (RR 16.0, 95% CI 15.2–17.0) vs. no prior HDP. Early-onset severe HDP (<28 weeks) carried the highest risk (22.9%, RR 23.1); prior HELLP conferred a 4.6% risk of recurrent HELLP (RR 61.0), and prior eclampsia a 1.1% risk of recurrent eclampsia (RR 40.1).","limitations":"Retrospective design with ICD-10 code–based identification risks misclassification of HDP subtypes. Only patients with two or more *observed* pregnancies in the same database were included, which may introduce selection bias. Outpatient care and long-term follow-up data were not captured.","practice_takeaway":"Counsel patients with prior severe HDP—especially early-onset (<28 weeks)—that their recurrence risk is substantially elevated (up to ~23%), warranting close surveillance in subsequent pregnancies. Prior HELLP or eclampsia also meaningfully raises risk of recurrent severe disease, even if absolute recurrence rates are lower."}},{"doi":"10.1097/aog.0000000000006396","pmid":"42561415","title":"Trends in Pregnancy-Related Mortality in the United States","journal_title":"Obstetrics & Gynecology","journal_issn":"0029-7844","published_at":"2026-08-07T00:00:00.000Z","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13472159/","source_score":7,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-08-21T06:28:17.910Z","updated_at":"2026-08-21T06:28:17.910Z","tags":[{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"condition","value":"Cardiovascular Disease in Pregnancy","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"condition","value":"COVID-19","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"condition","value":"Obstetric Hemorrhage","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"condition","value":"Pregnancy-Related Mortality","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"condition","value":"Sepsis in Pregnancy","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"impact_flag","value":"practice_changing","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"level_of_evidence","value":"3","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"sample_size","value":"n=14310","value_numeric":14310},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"study_design","value":"Surveillance / Descriptive Study","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"warning","value":"COVID-19 deaths were coded within the infection/sepsis category starting in 2020, making it difficult to isolate pandemic effects from baseline sepsis trends in prior periods.","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"warning","value":"No racial, ethnic, or socioeconomic subgroup data are reported in the abstract; disparities in maternal mortality — well-documented elsewhere — cannot be assessed from this summary.","value_numeric":null},{"paper_doi":"10.1097/aog.0000000000006396","tag_type":"warning","value":"The impact_flag 'practice_changing' reflects the public health significance of the hemorrhage trend and the cardiovascular mortality pattern, though this is a descriptive surveillance study without interventional data.","value_numeric":null}],"summaries":{"what_studied":"This CDC Pregnancy Mortality Surveillance System (PMSS) descriptive study analyzed underlying causes of 14,310 pregnancy-related deaths in the U.S. from 2005 to 2024, using Joinpoint regression to identify trends in overall and cause-specific pregnancy-related mortality ratios (PRMRs) across 5-year intervals.","key_result":"Cardiovascular conditions were the leading cause of pregnancy-related death in 17 of 20 years. The overall PRMR rose sharply from 2018–2021 (APC +20.11%, p<0.001), driven largely by COVID-19-related sepsis (APC +86.17%), then fell from 2021–2024 (APC −17.91%, p<0.001). Notably, hemorrhage deaths trended upward from 2017–2024 (APC +6.84%, p=0.02), a concern independent of COVID-19.","limitations":"- Descriptive surveillance data cannot establish causation or identify preventable factors.\n- COVID-19 deaths were folded into the infection/sepsis category starting in 2020, potentially inflating that category and complicating pre/post-pandemic comparisons.\n- Racial, socioeconomic, and geographic breakdowns are not reported in this abstract, limiting equity insights.","practice_takeaway":"Cardiovascular disease remains the top killer in pregnancy — clinicians should maintain high vigilance for cardiac conditions throughout the perinatal period. The persistent rise in hemorrhage deaths from 2017–2024 signals a need to reassess hemorrhage prevention and response protocols at the institutional level."}},{"doi":"10.1007/s12020-026-04701-9","pmid":"42536323","title":"Hypertensive disorders of pregnancy and GLP-1 receptor agonist timing: a systematic review and meta-analysis","journal_title":"Endocrine","journal_issn":"1559-0100","published_at":"2026-07-31T00:00:00.000Z","url":"https://doi.org/10.1007/s12020-026-04701-9","source_score":7,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-08-06T13:22:05.398Z","updated_at":"2026-08-06T13:22:05.398Z","tags":[{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"category","value":"Endocrinology & Metabolism","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"condition","value":"Obesity","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"condition","value":"Preeclampsia","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"condition","value":"Type 2 Diabetes Mellitus","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"generic","value":"albiglutide","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"generic","value":"dulaglutide","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"generic","value":"exenatide","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"generic","value":"liraglutide","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"generic","value":"lixisenatide","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"generic","value":"semaglutide","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"generic","value":"tirzepatide","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"impact_flag","value":"limited_evidence","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"level_of_evidence","value":"3","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"modality","value":"GLP-1 Receptor Agonist","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"sample_size","value":"n=10880","value_numeric":10880},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"study_design","value":"Systematic Review and Meta-Analysis","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"warning","value":"Only 3 retrospective cohort studies were pooled; high statistical heterogeneity across studies makes the pooled OR unreliable as a definitive estimate. The result should be interpreted cautiously.","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"warning","value":"The PROSPERO registration number (CRD420251273858) appears to contain a formatting irregularity in the source text; the actual registration may differ.","value_numeric":null},{"paper_doi":"10.1007/s12020-026-04701-9","tag_type":"warning","value":"Tirzepatide is a dual GIP/GLP-1 receptor agonist, not a pure GLP-1 RA; its inclusion alongside GLP-1 RAs may introduce additional heterogeneity.","value_numeric":null}],"summaries":{"what_studied":"This systematic review and meta-analysis examined whether periconceptional or first-trimester exposure to GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide, tirzepatide, exenatide, lixisenatide, albiglutide) was associated with hypertensive disorders of pregnancy (HDP), pooling data from 3 retrospective US cohort studies (2014–2025) covering 10,880 pregnancies (4,942 exposed, 5,938 unexposed).","key_result":"Pooled analysis showed no statistically significant association between GLP-1 RA exposure and HDP risk (OR 0.91, 95% CI 0.57–1.47); 2 of 3 studies found lower HDP risk in exposed women (ORs 0.56 and 0.84), while 1 found higher risk, with high heterogeneity across studies.","limitations":"- Only 3 retrospective cohort studies were available, all from the US, limiting generalizability.\n- Two studies relied on ICD-10 codes for HDP diagnosis, which may underreport or misclassify cases.\n- Abrupt GLP-1 RA discontinuation before conception may cause gestational weight rebound, confounding the HDP risk estimate.","practice_takeaway":"Current evidence does not support a significant protective or harmful effect of periconceptional or first-trimester GLP-1 RA use on HDP risk; clinicians should counsel patients that data are insufficient to guide decisions, and large prospective studies are needed before changing practice."}},{"doi":"10.1111/aogs.70304","pmid":"42383805","title":"Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register‐based cohort study","journal_title":"Acta Obstetricia et Gynecologica Scandinavica","journal_issn":"0001-6349","published_at":"2026-07-01T00:00:00.000Z","url":"https://doi.org/10.1111/aogs.70304","source_score":7,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-07-16T13:37:15.851Z","updated_at":"2026-07-16T13:37:15.851Z","tags":[{"paper_doi":"10.1111/aogs.70304","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"condition","value":"Cervical Intraepithelial Neoplasia","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"condition","value":"Gestational Diabetes Mellitus","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"condition","value":"Human Papillomavirus Infection","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"condition","value":"Small for Gestational Age","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"generic","value":"large loop excision of the transformation zone","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"impact_flag","value":"confirms_prior","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"level_of_evidence","value":"3","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"modality","value":"Surgical Excision","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"sample_size","value":"n=10537","value_numeric":10537},{"paper_doi":"10.1111/aogs.70304","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"study_design","value":"Register-Based Cohort Study","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"warning","value":"Level of evidence assigned as 3 (cohort study) given the register-based, non-randomized design; randomized data on this question are lacking.","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"warning","value":"LLETZ is used here as a generic term for cervical excision; the study does not differentiate by depth or extent of excision, which may affect pregnancy outcomes independently.","value_numeric":null},{"paper_doi":"10.1111/aogs.70304","tag_type":"warning","value":"The cohort is restricted to women who subsequently gave birth, which may underestimate adverse outcomes if CIN2 management influenced fertility or pregnancy loss rates.","value_numeric":null}],"summaries":{"what_studied":"This nationwide Danish register-based cohort study compared adverse pregnancy outcomes (hypertensive disorders of pregnancy, small for gestational age [SGA], and gestational diabetes mellitus [GDM]) in women aged 18–40 with a first-time CIN2 diagnosis (1998–2018) who underwent active surveillance (n=4,430) versus immediate LLETZ (n=6,107), followed through a subsequent singleton birth.","key_result":"No meaningful difference was found between active surveillance and LLETZ for any outcome: hypertensive disorders of pregnancy (aRR 1.08, 95% CI 0.91–1.29), SGA (aRR 0.94, 95% CI 0.74–1.19), or GDM (aRR 0.92, 95% CI 0.73–1.16); absolute rates were 5.2%, 3.6%, and 3.0%, respectively.","limitations":"- Register-based design limits capture of unmeasured confounders (e.g., smoking, BMI, sexual behavior) that may affect both CIN2 management choice and pregnancy outcomes.\n- Study includes only women who had a subsequent birth, introducing potential selection bias (women with the most severe outcomes may not have become pregnant).\n- CIN2 is a heterogeneous lesion; histological grade and HPV type were not consistently available to adjust for disease severity.","practice_takeaway":"Clinicians can reassure women with CIN2 that choosing active surveillance over immediate LLETZ does not appear to raise their risk of hypertensive disorders, SGA, or GDM in future pregnancies. This supports active surveillance as a safe fertility-preserving option without additional obstetric risk."}},{"doi":"10.1186/s12884-026-09536-w","pmid":"42366411","title":"A prospective longitudinal interventional cohort study on maternal nutrition and pregnancy outcomes in urban Cameroon (CAMELIA): study protocol","journal_title":"BMC Pregnancy and Childbirth","journal_issn":"1471-2393","published_at":"2026-06-29T00:00:00.000Z","url":"https://doi.org/10.1186/s12884-026-09536-w","source_score":2,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-07-01T13:27:24.690Z","updated_at":"2026-07-01T13:27:24.690Z","tags":[{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"condition","value":"Anaemia in Pregnancy","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"condition","value":"Gestational Hyperglycaemia","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"condition","value":"Low Birth Weight","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"condition","value":"Maternal Malnutrition","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"condition","value":"Preterm Birth","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"impact_flag","value":"limited_evidence","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"level_of_evidence","value":"3","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"modality","value":"Digital Health Support","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"modality","value":"Nutritional Intervention","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"sample_size","value":"n=1200","value_numeric":1200},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"study_design","value":"Prospective Longitudinal Interventional Cohort Study","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"warning","value":"Level of evidence assigned as 3 (cohort study design); final rating may change depending on how results are reported and analyzed.","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"warning","value":"The registration date (14 August 2025) is listed as future relative to the paper's publication date of 29 June 2026; this may reflect a retrospective or provisional registration, which is a potential risk-of-bias concern.","value_numeric":null},{"paper_doi":"10.1186/s12884-026-09536-w","tag_type":"warning","value":"This is a study protocol published before results are available — no efficacy, safety, or outcome data can be extracted.","value_numeric":null}],"summaries":{"what_studied":"The CAMELIA study is a prospective longitudinal interventional cohort enrolling 1,200 pregnant women (<22 weeks' gestation) in Yaoundé, Cameroon, evaluating a structured multi-modal nutritional intervention (SUN-APP) on maternal and neonatal outcomes, with follow-up through 42 days postpartum.","key_result":"This is a study protocol; no outcome results are yet available. Primary outcomes are feasibility and acceptability of the SUN-APP intervention. Secondary outcomes include rates of gestational hyperglycaemia (screened by fasting capillary glucose ≥92 mg/dL), hypertensive disorders, anaemia, low birth weight, and preterm birth.","limitations":"- Protocol paper only — no efficacy or outcome data are reported yet.\n- Single urban facility in Yaoundé limits generalizability to rural or other African settings.\n- Follow-up ends at 42 days postpartum, restricting assessment of longer-term metabolic outcomes despite stated aims.","practice_takeaway":"The SUN-APP framework — combining individual counselling, group education, workshops, and WhatsApp/SMS support — offers a practical model for integrating nutritional screening into routine antenatal care in low-resource settings. Clinicians in similar contexts can watch for CAMELIA's results to inform gestational metabolic disorder prevention strategies."}},{"doi":"10.1002/ijgo.71103","pmid":"42223974","title":"Rare vasculitis types and obstetric and neonatal outcomes – A population‐based study","journal_title":"International Journal of Gynecology & Obstetrics","journal_issn":"0020-7292","published_at":"2026-06-01T00:00:00.000Z","url":"https://doi.org/10.1002/ijgo.71103","source_score":1,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-06-10T14:23:55.399Z","updated_at":"2026-06-10T14:23:55.399Z","tags":[{"paper_doi":"10.1002/ijgo.71103","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"condition","value":"Giant Cell Arteritis","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"condition","value":"Kawasaki Disease","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"condition","value":"Polyarteritis Nodosa","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"condition","value":"Preterm Delivery","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"condition","value":"Takayasu Arteritis","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"condition","value":"Vasculitis","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"condition","value":"Wegener's Granulomatosis","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"impact_flag","value":"limited_evidence","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"level_of_evidence","value":"3","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"sample_size","value":"n=9096788","value_numeric":9096788},{"paper_doi":"10.1002/ijgo.71103","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"study_design","value":"Retrospective Cohort Study","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"warning","value":"ICD-9 coding is used for diagnosis; rare conditions may be under-coded or miscoded in administrative databases.","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"warning","value":"No information on vasculitis disease activity, flares during pregnancy, or specific immunosuppressive medications is available in the dataset, limiting causal inference.","value_numeric":null},{"paper_doi":"10.1002/ijgo.71103","tag_type":"warning","value":"The vasculitis group is very small (n=335 out of >9 million), so individual subtype-level analyses are not reported and estimates should be interpreted cautiously.","value_numeric":null}],"summaries":{"what_studied":"This retrospective cohort study used the HCUP-NIS database (2004–2014) to compare obstetric and perinatal outcomes in pregnant US women with rare vasculitis subtypes (polyarteritis nodosa, Kawasaki disease, hypersensitivity angiitis, Wegener's granulomatosis, giant cell arteritis, Takayasu arteritis) versus those without, among 9,096,788 deliveries.","key_result":"Only 335 women (3.7/100,000) had rare vasculitis. Compared to controls, they had significantly higher rates of hypertensive disorders of pregnancy (aOR 1.89), preterm delivery (aOR 1.76), blood transfusion (aOR 3.68), cesarean delivery (aOR 1.31), and congenital anomalies (aOR 4.1); placental abruption, hysterectomy, and VTE were comparable between groups.","limitations":"- Extremely small vasculitis group (n=335) limits statistical power and subgroup analysis by vasculitis type.\n- Retrospective ICD-9 coding may misclassify or undercount rare vasculitis diagnoses.\n- Database lacks disease activity, medication use (e.g., immunosuppressants), and disease severity data, which are key confounders.","practice_takeaway":"Pregnant women with rare vasculitis should be counseled about elevated risks of hypertensive disorders, preterm birth, cesarean delivery, and fetal congenital anomalies, and managed with close maternal-fetal medicine surveillance. Blood transfusion risk is notably high (aOR 3.68), warranting proactive hemorrhage planning."}},{"doi":"10.1093/humrep/deag084","pmid":"42204604","title":"Obstetric outcomes after IVF/ICSI treatment in women with endometriosis and/or adenomyosis diagnosed by ultrasonography: a prospective cohort study","journal_title":"Human Reproduction","journal_issn":"0268-1161","published_at":"2026-05-27T00:00:00.000Z","url":"https://doi.org/10.1093/humrep/deag084","source_score":1,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-06-06T13:22:53.389Z","updated_at":"2026-06-06T13:22:53.389Z","tags":[{"paper_doi":"10.1093/humrep/deag084","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"condition","value":"Adenomyosis","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"condition","value":"Endometriosis","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"condition","value":"Placenta Previa","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"condition","value":"Preterm Birth","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"impact_flag","value":"confirms_prior","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"level_of_evidence","value":"2","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"modality","value":"Assisted Reproductive Technology","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"sample_size","value":"n=607","value_numeric":607},{"paper_doi":"10.1093/humrep/deag084","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"study_design","value":"Prospective Cohort Study","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"warning","value":"8.9% loss to follow-up may introduce selection bias if obstetric outcomes differed in the missing group.","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"warning","value":"Diagnosis was based solely on ultrasound (IDEA/MUSA criteria); superficial peritoneal endometriosis—detectable only surgically—was not captured, potentially underestimating disease burden.","value_numeric":null},{"paper_doi":"10.1093/humrep/deag084","tag_type":"warning","value":"The composite 'endometriosis and/or adenomyosis' group pools biologically distinct conditions; disease-specific risk estimates should be interpreted cautiously.","value_numeric":null}],"summaries":{"what_studied":"This prospective cohort study examined obstetric outcomes in 607 women who conceived via IVF/ICSI, comparing those with ultrasound-diagnosed endometriosis and/or adenomyosis (n=144, 23.7%) to disease-free women (n=463), using IDEA and revised MUSA criteria.","key_result":"Women with endometriosis and/or adenomyosis had significantly higher rates of preterm birth (18.9% vs 11.4%; aRR 1.63, 95% CI 1.06–2.49), driven by late preterm birth (16% vs 8%; aRR 2.56). They also faced elevated risk of placenta previa (9.0% vs 1.5%; aRR 5.82), antepartum hemorrhage (11.8% vs 6.5%; aRR 2.02), hypertensive disorders of pregnancy (13.2% vs 6.7%; aRR 2.26), and pelvic pain (16.7% vs 8.6%; aRR 1.91). Caesarean delivery, gestational diabetes, placental abruption, and postpartum hemorrhage were not significantly increased.","limitations":"- Study excludes women ≥40 years or BMI ≥30, limiting generalizability.\n- Superficial peritoneal endometriosis was not captured by ultrasound and not accounted for.\n- Underpowered for several secondary outcomes; the combined endometriosis/adenomyosis group is dominated by isolated endometriosis, potentially masking adenomyosis-specific effects.","practice_takeaway":"Clinicians should counsel women with ultrasound-diagnosed endometriosis and/or adenomyosis who conceive via IVF/ICSI about meaningfully higher risks of preterm birth, placenta previa, antepartum hemorrhage, and hypertensive disorders, and consider enhanced antenatal surveillance for these complications."}},{"doi":"10.1016/j.jacc.2025.11.001","pmid":"42171544","title":"Optimization of Postpartum Care for Patients With and at Risk for Premature and Long-Term Cardiovascular Disease: 2026 ACC Expert Consensus Decision Pathway","journal_title":"JACC","journal_issn":"0735-1097","published_at":"2026-05-22T00:00:00.000Z","url":"https://doi.org/10.1016/j.jacc.2025.11.001","source_score":55,"is_retracted":false,"is_open_access":false,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-05-27T15:43:03.282Z","updated_at":"2026-05-27T15:43:03.282Z","tags":[{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"category","value":"Cardiac & Cardiovascular Systems","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"condition","value":"Cardiovascular Disease","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"condition","value":"Gestational Hypertension","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"condition","value":"Postpartum Hypertension","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"condition","value":"Preeclampsia","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"generic","value":"amlodipine","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"generic","value":"enalapril","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"generic","value":"labetalol","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"generic","value":"nifedipine","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"impact_flag","value":"practice_changing","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"level_of_evidence","value":"5","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"modality","value":"ACE Inhibitor","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"modality","value":"Beta Blocker","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"modality","value":"Calcium Channel Blocker","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"modality","value":"Remote Blood Pressure Monitoring","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"study_design","value":"Expert Consensus / Clinical Practice Toolkit","value_numeric":null},{"paper_doi":"10.1016/j.jacc.2025.11.001","tag_type":"warning","value":"This document is a clinical toolkit and expert consensus statement, not a primary research study; level of evidence reflects expert opinion throughout. No sample size is applicable. The publication date in the DOI (2026-05-22) is consistent with the 2026 ACC Expert Consensus designation, though PDF metadata shows a 2024 creation date, suggesting the document was in preparation for some time before publication. BP titration targets in the fourth trimester are explicitly acknowledged by the authors as lacking high-quality trial evidence.","value_numeric":null}],"summaries":{"what_studied":"This ACC expert consensus toolkit provides a practical framework for establishing and operating postpartum hypertension clinics for individuals with hypertensive disorders of pregnancy (HDP), covering clinic models, staffing, BP management protocols, medication titration, remote monitoring, contraception, and cardiovascular risk counseling.","key_result":"Key guidance includes: start antihypertensives when BP ≥140/90 mmHg on 2+ occasions; target BP <140/90 mmHg early postpartum, then <130/80 mmHg long-term; first-line agents are nifedipine XL 30 mg daily, enalapril 5 mg daily, or amlodipine 5 mg daily (all safe with breastfeeding). Over 40% of patients with severe preeclampsia remain hypertensive at 1 year postpartum; the POP-HT RCT showed improved BP control with remote monitoring. HDP recurrence risk is ~21%.","limitations":"This is a consensus-based toolkit, not a systematic review or RCT; most specific numerical recommendations (e.g., BP titration intervals) are expert opinion, not derived from high-quality postpartum-specific trial data. Optimal BP targets throughout the fourth trimester are described as an 'evidence-free space.'","practice_takeaway":"Clinicians should schedule a BP check within 7–10 days of delivery for all HDP patients, initiate antihypertensives at BP ≥140/90 mmHg, and counsel every patient that HDP carries a cardiovascular risk comparable to smoking or diabetes. Telemedicine and remote BP monitoring improve retention and BP control; avoid combined hormonal contraceptives (estrogen-containing) in patients with uncontrolled hypertension (BP ≥160/100 mmHg)."}},{"doi":"10.1016/j.preghy.2026.101473","pmid":"42105509","title":"Are we overlooking ultra-processed foods in preeclampsia?","journal_title":"Pregnancy Hypertension","journal_issn":"2210-7789","published_at":"2026-05-10T00:00:00.000Z","url":"https://doi.org/10.1016/j.preghy.2026.101473","source_score":3,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2026-05-11","doi":"10.1016/j.preghy.2026.101473","days":"7","issn":"2210-7789","rank":"8","field":"Clinical Medicine","score":"3","category":"Obstetrics & Gynecology","categories":["Obstetrics & Gynecology"],"_categories":["Obstetrics & Gynecology"]},"pubmed":{"doi":"10.1016/j.preghy.2026.101473","title":"Are we overlooking ultra-processed foods in preeclampsia?","journal":"Pregnancy hypertension","methods":"","results":"","abstract":"Ultra-processed foods (UPFs) are a hallmark of unhealthy dietary patterns and have been linked to chronic low-grade inflammation, insulin resistance, and obesity - key risk factors for preeclampsia (PE). Growing epidemiological evidence associates UPF-rich dietary patterns with increased risk of hypertensive disorders of hypertension (HDP), including PE. UPFs may promote PE pathophysiology through inflammation, gut microbiota dysbiosis, immune dysregulation, oxidative stress, endothelial dysfunction, and angiogenic imbalance. In this narrative review we synthesize the epidemiological and mechanistic evidence linking UPF consumption to PE and claim that recognizing UPFs as a modifiable dietary risk factor represents a meaningful and underexplored opportunity for PE prevention.","keywords":["Dietary pattern","Hypertensive disorders of pregnancy","Nutrition","Preeclampsia","Ultra-processed foods"],"pubmed_id":"42105509","conclusions":"","publication_date":"2026-05-10T00:00:00"},"crossref":{"DOI":"10.1016/j.preghy.2026.101473","URL":"https://doi.org/10.1016/j.preghy.2026.101473","ISSN":["2210-7789"],"link":[{"URL":"https://api.elsevier.com/content/article/PII:S2210778926000619?httpAccept=text/xml","content-type":"text/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https://api.elsevier.com/content/article/PII:S2210778926000619?httpAccept=text/plain","content-type":"text/plain","content-version":"vor","intended-application":"text-mining"}],"page":"101473","type":"journal-article","issue":null,"score":1,"title":["Are we overlooking ultra-processed foods in preeclampsia?"],"author":[{"given":"Priscila Oliveira","family":"Barbosa","sequence":"first","affiliation":[]},{"given":"Aline Souza","family":"Costa","sequence":"additional","affiliation":[]},{"given":"Priscila Rezeck","family":"Nunes","sequence":"additional","affiliation":[]},{"given":"Andrew","family":"Shennan","sequence":"additional","affiliation":[]},{"given":"Ricardo Carvalho","family":"Cavalli","sequence":"additional","affiliation":[]},{"given":"Valeria Cristina","family":"Sandrim","sequence":"additional","affiliation":[]}],"funder":[{"id":[{"id":"10.13039/501100001807","id-type":"DOI","asserted-by":"publisher"}],"DOI":"10.13039/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher"},{"id":[{"id":"10.13039/501100003593","id-type":"DOI","asserted-by":"publisher"}],"DOI":"10.13039/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher"}],"issued":{"date-parts":[[2026,6]]},"member":"78","prefix":"10.1016","source":"Crossref","volume":"44","created":{"date-time":"2026-05-08T13:50:46Z","timestamp":1778248246000,"date-parts":[[2026,5,8]]},"indexed":{"date-time":"2026-05-08T22:11:58Z","timestamp":1778278318100,"date-parts":[[2026,5,8]]},"license":[{"URL":"https://www.elsevier.com/tdm/userlicense/1.0/","start":{"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000,"date-parts":[[2026,6,1]]},"delay-in-days":0,"content-version":"tdm"},{"URL":"https://www.elsevier.com/legal/tdmrep-license","start":{"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000,"date-parts":[[2026,6,1]]},"delay-in-days":0,"content-version":"tdm"},{"URL":"http://creativecommons.org/licenses/by/4.0/","start":{"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000,"date-parts":[[2026,4,22]]},"delay-in-days":0,"content-version":"vor"}],"subject":[],"abstract":null,"language":"en","relation":{},"resource":{"primary":{"URL":"https://linkinghub.elsevier.com/retrieve/pii/S2210778926000619"}},"subtitle":[],"assertion":[{"name":"publisher","label":"This article is maintained by","value":"Elsevier"},{"name":"articletitle","label":"Article Title","value":"Are we overlooking ultra-processed foods in preeclampsia?"},{"name":"journaltitle","label":"Journal Title","value":"Pregnancy Hypertension"},{"name":"articlelink","label":"CrossRef DOI link to publisher maintained version","value":"https://doi.org/10.1016/j.preghy.2026.101473"},{"name":"content_type","label":"Content Type","value":"article"},{"name":"copyright","label":"Copyright","value":"© 2026 The Authors. 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Published by Elsevier Inc."}],"deposited":{"date-time":"2026-05-14T01:20:37Z","timestamp":1778721637000,"date-parts":[[2026,5,14]]},"issn-type":[{"type":"print","value":"0002-9378"}],"published":{"date-parts":[[2026,4]]},"publisher":"Elsevier BV","reference":null,"short-title":[],"update-policy":"https://doi.org/10.1016/elsevier_cm_policy","alternative-id":["S0002937826002103"],"content-domain":{"domain":["ajog.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"original-title":[],"container-title":["American Journal of Obstetrics and Gynecology"],"published-print":{"date-parts":[[2026,4]]},"reference-count":0,"published-online":null,"references-count":0,"short-container-title":["American Journal of Obstetrics and Gynecology"],"is-referenced-by-count":0},"unpaywall":{"doi":"10.1016/j.ajog.2026.04.025","is_oa":true,"title":"A randomized controlled trial comparing remote blood pressure monitoring with office-based blood pressure monitoring for women at high risk of preeclampsia","updated":"2026-04-22T09:11:45+00:00","published_date":"2026-04-01","best_oa_location":{"url":"https://doi.org/10.1016/j.ajog.2026.04.025","pmh_id":null,"url_for_pdf":null,"url_for_landing_page":"https://doi.org/10.1016/j.ajog.2026.04.025"}}},"created_at":"2026-05-07T22:49:41.119Z","updated_at":"2026-05-14T15:13:26.918Z","tags":[{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"condition","value":"Preeclampsia","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"impact_flag","value":"practice_changing","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"level_of_evidence","value":"2","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"modality","value":"Antihypertensive Therapy","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"modality","value":"Remote Patient Monitoring","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"sample_size","value":"n=270","value_numeric":270},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"study_design","value":"Randomized Controlled Trial","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"warning","value":"Brand name of the specific automated BP device/smartphone app used is not reported in the abstract, which may affect reproducibility.","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"warning","value":"The paper's DOI reflects a 2026 publication date, which is consistent with today's date but is ahead of typical indexing — verify final published version for any post-acceptance changes.","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"warning","value":"The primary composite outcome (HR 1.0, wide CI 0.57–1.76) is consistent with non-inferiority, but the upper CI boundary should be checked against the trial's pre-specified margin.","value_numeric":null},{"paper_doi":"10.1016/j.ajog.2026.04.025","tag_type":"warning","value":"The trial is described as 'non-inferiority' but the abstract does not specify the pre-defined non-inferiority margin, making it difficult to fully assess whether non-inferiority was formally demonstrated.","value_numeric":null}],"summaries":{"what_studied":"Unblinded non-inferiority RCT (n=270) comparing remote blood pressure monitoring (self-measured via automated device + smartphone app with specialist review) vs. in-person specialist hypertension clinic visits in pregnant women at high risk of preeclampsia, across 3 Australian hospitals (July 2022–February 2024).","key_result":"No difference in the perinatal composite outcome (perinatal loss, high-level neonatal care >48h, or SGA <10th centile; HR 1.0, 95% CI 0.57–1.76; p=0.99). Remote monitoring reduced total antenatal visits (median 14 vs. 16; p<0.01), planned outpatient appointments (10 vs. 13; p<0.01), any-cause hospital admission (HR 0.54, 95% CI 0.30–0.97; p=0.04), and hypertension-specific admission (HR 0.41, 95% CI 0.19–0.88; p=0.02). More antihypertensive prescriptions were filled in the remote arm (median 5 vs. 3; p<0.01).","limitations":"- Unblinded design may introduce performance or detection bias.\n- Single-country, 3-centre metropolitan sample (60% non-Caucasian) limits global generalisability.\n- Non-inferiority margin and statistical power assumptions are not detailed in the abstract, making it hard to assess whether the trial was adequately sized for the primary composite.","practice_takeaway":"For pregnant women at high risk of preeclampsia, remote BP monitoring can safely replace frequent specialist clinic visits — reducing office attendances and hospital admissions without worsening fetal or maternal outcomes. Clinicians should also note that remote monitoring appears to improve antihypertensive medication adherence."}},{"doi":"10.1111/1471-0528.70251","pmid":"42017268","title":"Long‐Term Cardiovascular Impact of Postpartum Treatment After Hypertensive Disorders of Pregnancy: Population‐Based Cohort Study","journal_title":"BJOG: An International Journal of Obstetrics & Gynaecology","journal_issn":"1470-0328","published_at":"2026-04-22T00:00:00.000Z","url":"https://doi.org/10.1111/1471-0528.70251","source_score":7,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-05-07T22:50:49.189Z","updated_at":"2026-05-07T22:50:49.189Z","tags":[{"paper_doi":"10.1111/1471-0528.70251","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"condition","value":"Cerebrovascular Disease","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"condition","value":"Chronic Hypertension","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"condition","value":"Coronary Artery Disease","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"condition","value":"Heart Failure","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"condition","value":"Peripheral Artery Disease","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"impact_flag","value":"practice_changing","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"level_of_evidence","value":"3","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"modality","value":"Antihypertensive Agent","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"sample_size","value":"n=108,906","value_numeric":108906},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"study_design","value":"Population-Based Cohort Study","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"warning","value":"Results are from a French administrative database (2010–2014); generalizability to other health systems or more recent practice may be limited.","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"warning","value":"The higher cardiovascular risk in treated women likely reflects confounding by indication (i.e., more severe or persistent HDP), not a harmful effect of antihypertensive treatment itself — clinicians should not interpret this as a reason to withhold postpartum treatment.","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70251","tag_type":"warning","value":"The study does not report which specific antihypertensive agents were used, limiting drug-level clinical applicability.","value_numeric":null}],"summaries":{"what_studied":"This nationwide population-based cohort study in France evaluated whether early postpartum antihypertensive treatment (within 1 month of delivery) influences long-term cardiovascular outcomes over 10 years in 108,906 women with hypertensive disorders of pregnancy (HDP), excluding those with pre-existing chronic hypertension, who delivered between 2010 and 2014.","key_result":"Women treated early postpartum had significantly higher 10-year cardiovascular risk vs. untreated women: new-onset chronic hypertension (CH) aHR 3.07 (44% vs. 18% absolute risk), composite event including CH aHR 3.03, and composite excluding CH aHR 1.45. Treated women also developed events earlier in the postpartum period.","limitations":"Observational design limits causal inference — treated women likely had more severe HDP at baseline, introducing residual confounding by indication. The study cannot distinguish whether treatment itself drives outcomes or merely marks higher-risk women. Postpartum follow-up data rely on administrative health records, which may miss clinical nuance.","practice_takeaway":"All women with HDP — not just those requiring postpartum antihypertensives — need structured long-term cardiovascular follow-up, as ~1 in 5 untreated women still developed chronic hypertension within 10 years. Clinicians should use HDP as a trigger for ongoing BP monitoring and cardiovascular risk reduction regardless of whether medication was prescribed postpartum."}},{"doi":"10.1002/acr.80048","pmid":"41869994","title":"Adverse Pregnancy Outcomes in Adult Patients With Idiopathic Inflammatory Myopathy: A Systematic Review and Meta‐Analysis","journal_title":"Arthritis Care & Research","journal_issn":"2151-464X","published_at":"2026-04-21T00:00:00.000Z","url":"https://doi.org/10.1002/acr.80048","source_score":6,"is_retracted":false,"is_open_access":false,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-05-07T22:49:23.429Z","updated_at":"2026-05-07T22:49:23.429Z","tags":[{"paper_doi":"10.1002/acr.80048","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"category","value":"Rheumatology","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"condition","value":"Adverse Pregnancy Outcomes","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"condition","value":"Dermatomyositis","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"condition","value":"Hypertensive Disorders of Pregnancy","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"condition","value":"Idiopathic Inflammatory Myopathy","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"condition","value":"Intrauterine Growth Restriction","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"condition","value":"Polymyositis","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"condition","value":"Preterm Birth","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"impact_flag","value":"safety_signal","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"level_of_evidence","value":"2","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"sample_size","value":"5 cohorts","value_numeric":5},{"paper_doi":"10.1002/acr.80048","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"study_design","value":"Systematic Review and Meta-Analysis","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"warning","value":"High heterogeneity (I² up to 79%) was observed for several outcomes, particularly cesarean section, which limits confidence in pooled estimates.","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"warning","value":"Publication date is listed as April 21, 2026, which is in the future relative to the paper's own search cutoff (May 15, 2025) — no data integrity issue identified, but noted for context.","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"warning","value":"Results are predominantly driven by dermatomyositis and polymyositis; generalizability to rarer IIM subtypes (e.g., anti-synthetase syndrome, immune-mediated necrotizing myopathy) is uncertain.","value_numeric":null},{"paper_doi":"10.1002/acr.80048","tag_type":"warning","value":"Sample size tag reflects number of included studies (n=5 cohorts), not total patient count — individual patient N was not reported in the abstract.","value_numeric":null}],"summaries":{"what_studied":"This systematic review and meta-analysis evaluated adverse pregnancy outcomes in adult patients with idiopathic inflammatory myopathy (IIM) — predominantly dermatomyositis or polymyositis — compared to pregnant patients without IIM, pooling data from five population-based retrospective cohorts identified through searches up to May 15, 2025.","key_result":"IIM was associated with significantly higher risks of hypertensive disorders of pregnancy (OR 2.73, 95% CI 1.76–4.23), cesarean section (OR 2.03, 95% CI 1.37–3.00), preterm birth (OR 3.71, 95% CI 2.35–5.85), and small for gestational age or intrauterine growth restriction (OR 1.90, 95% CI 1.03–3.51).","limitations":"- Only five studies were included, all retrospective cohorts, limiting statistical power and causal inference.\n- Results predominantly reflect dermatomyositis and polymyositis subtypes; findings may not generalize to other IIM subtypes (e.g., anti-synthetase syndrome, immune-mediated necrotizing myopathy).\n- Residual confounding by disease activity and treatment (e.g., immunosuppressants, corticosteroids) could not be fully excluded.","practice_takeaway":"Clinicians should counsel patients with IIM — especially those with dermatomyositis or polymyositis — about substantially elevated risks of preterm birth, hypertensive disorders, and fetal growth restriction during pregnancy. Close obstetric monitoring and multidisciplinary rheumatology-maternal-fetal medicine co-management are warranted."}},{"doi":"10.1161/jaha.125.042477","pmid":"41532530","title":"Hypertensive Disorders of Pregnancy in Asian American, Native Hawaiian, and Pacific Islander Individuals in California, 2007 to 2019","journal_title":"Journal of the American Heart Association","journal_issn":"2047-9980","published_at":"2026-01-14T00:00:00.000Z","url":"https://doi.org/10.1161/jaha.125.042477","source_score":52,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2026-01-16","doi":"10.1161/jaha.125.042477","days":"7","issn":"2047-9980","rank":"9","field":"Clinical Medicine","score":"52","category":"Cardiac & Cardiovascular Systems","categories":["Cardiac & Cardiovascular Systems"],"_categories":["Cardiac & Cardiovascular Systems"]},"pubmed":{"doi":"10.1161/JAHA.125.042477","title":"Hypertensive Disorders of Pregnancy in Asian American, Native Hawaiian, and Pacific Islander Individuals in California, 2007 to 2019.","journal":"Journal of the American Heart Association","methods":"","results":"The cohort included 772 688 individuals. Prevalence of HDPs ranged from 3.7% among Chinese individuals (n=7930) to 13.0% among Guamanian individuals (n=247). All Pacific Islander subgroups and Filipino individuals were consistently at higher risk for HDPs than Chinese individuals, whereas Korean, Vietnamese, and Japanese individuals tended to be at lowest risk. After full adjustment, the highest risk groups had adjusted relative risks 2- to 3-fold higher than Chinese individuals.","abstract":"$32","keywords":["hypertensive disorders","maternal health","racial and ethnic disparities","social determinants of health"],"pubmed_id":"41532530","conclusions":"","publication_date":"2026-01-14T00:00:00"},"crossref":{"DOI":"10.1161/jaha.125.042477","URL":"https://doi.org/10.1161/jaha.125.042477","ISSN":["2047-9980"],"link":[{"URL":"https://www.ahajournals.org/doi/full/10.1161/JAHA.125.042477","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":null,"type":"journal-article","issue":null,"score":1,"title":["Hypertensive Disorders of Pregnancy in Asian American, Native Hawaiian, and Pacific Islander Individuals in California, 2007 to 2019"],"author":[{"given":"Jennifer","family":"Soh","sequence":"first","affiliation":[{"name":"Stanford University School of Medicine"}]},{"given":"Marina","family":"Carvalho Magalhães","sequence":"additional","affiliation":[{"name":"Stanford Medicine Children’s Health"},{"name":"Stanford University School of Medicine"}]},{"given":"Chen","family":"Ma","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine"}]},{"given":"Sandra","family":"Tsai","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine"}]},{"given":"Elliott K","family":"Main","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine"}]},{"given":"Suzan L","family":"Carmichael","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine"},{"name":"Stanford University School of Medicine"}]}],"issued":{"date-parts":[[2026,1,14]]},"member":"276","prefix":"10.1161","source":"Crossref","volume":null,"created":{"date-time":"2026-01-14T11:45:47Z","timestamp":1768391147000,"date-parts":[[2026,1,14]]},"indexed":{"date-time":"2026-01-15T07:57:17Z","timestamp":1768463837777,"date-parts":[[2026,1,15]]},"subject":[],"abstract":"$33","language":"en","relation":{},"resource":{"primary":{"URL":"https://www.ahajournals.org/doi/10.1161/JAHA.125.042477"}},"subtitle":[],"assertion":[{"name":"received","group":{"name":"publication_history","label":"Publication History"},"label":"Received","order":0,"value":"2025-04-02"},{"name":"accepted","group":{"name":"publication_history","label":"Publication History"},"label":"Accepted","order":2,"value":"2025-11-10"},{"name":"published","group":{"name":"publication_history","label":"Publication History"},"label":"Published","order":3,"value":"2026-01-14"}],"deposited":{"date-time":"2026-01-14T11:45:49Z","timestamp":1768391149000,"date-parts":[[2026,1,14]]},"issn-type":[{"type":"electronic","value":"2047-9980"}],"published":{"date-parts":[[2026,1,14]]},"publisher":"Ovid Technologies (Wolters Kluwer Health)","reference":[{"DOI":"10.15585/mmwr.mm7117a1","key":"e_1_3_1_2_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1001/jama.2023.16991","key":"e_1_3_1_3_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":null,"key":"e_1_3_1_4_2","year":"2023","issue":null,"author":"Luger RK","volume":null,"first-page":null,"unstructured":"Luger RK, Kight BP. 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All Pacific Islander subgroups and Filipino individuals had higher risk than Chinese, while Korean, Vietnamese, and Japanese had lower risk; after full adjustment, the highest-risk groups had adjusted RRs 2–3 times those of Chinese.","practice_takeaway":"HDP risk varies widely across disaggregated Asian American, Native Hawaiian, and Pacific Islander subgroups; Pacific Islander and Filipino patients are at comparatively higher risk. Clinicians should use subgroup risk differences to target prevention, prompt diagnosis, and treatment of HDPs."}}],"initialOffset":15,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"condition","value":"Hypertensive Disorders of Pregnancy"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Conditions","href":"/hub/tag/condition"},{"name":"Hypertensive Disorders of Pregnancy"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"condition","hub_tag_value":"Hypertensive Disorders of Pregnancy"}}}]]

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