JAMA Dermatology

<jats:sec id="ab-doi240021-1"><jats:title>Importance</jats:title><jats:p>Seborrheic dermatitis is a prevalent chronic inflammatory skin disease, yet its global prevalence, pathogenesis, and epidemiology remain inadequately defined.</jats:p></jats:sec><jats:sec id="ab-doi240021-2"><jats:title>Objective</jats:title><jats:p>To provide a detailed estimation of the global prevalence of seborrheic dermatitis, analyze demographic variations, and explore differences in various settings.</jats:p></jats:sec><jats:sec id="ab-doi240021-3"><jats:title>Data Sources</jats:title><jats:p>Embase, PubMed, Scopus, and Cochrane Database of Systematic Reviews were searched from inception through October 2023.</jats:p></jats:sec><jats:sec id="ab-doi240021-4"><jats:title>Study Selection</jats:title><jats:p>Original investigations on seborrheic dermatitis prevalence were included after duplicate screening of titles, abstracts, and full articles, including only studies with clinician-diagnosed cases.</jats:p></jats:sec><jats:sec id="ab-doi240021-5"><jats:title>Data Extraction and Synthesis</jats:title><jats:p>Following PRISMA guidelines, data were extracted and quality was assessed independently by multiple reviewers. A random-effects model using restricted maximum likelihood was used for meta-analysis and subgroup analyses.</jats:p></jats:sec><jats:sec id="ab-doi240021-6"><jats:title>Main Outcome and Measure</jats:title><jats:p>The primary outcome was the pooled estimate of global seborrheic dermatitis prevalence.</jats:p></jats:sec><jats:sec id="ab-doi240021-7"><jats:title>Results</jats:title><jats:p>From 1574 identified articles, 121 studies were included, encompassing 1 260 163 individuals and revealing a pooled global seborrheic dermatitis prevalence of 4.38% (95% CI, 3.58%-5.17%), with significant heterogeneity (<jats:italic>I<jats:sup>2</jats:sup></jats:italic> = 99.94%). Subgroup analyses showed variations by age, with a higher prevalence in adults (5.64% [95% CI, 4.01%-7.27%]) compared to children (3.70% [95% CI, 2.69%-4.80%]) and neonates (0.23% [95% CI, 0.04%-0.43%]). Geographic analyses indicated variability, with the highest prevalence in South Africa (8.82% [95% CI, 3.00%-14.64%]) and the lowest in India (2.62% [95% CI, 1.33%-3.92%]).</jats:p></jats:sec><jats:sec id="ab-doi240021-8"><jats:title>Conclusions and Relevance</jats:title><jats:p>This comprehensive meta-analysis provides a detailed estimation of the global prevalence of seborrheic dermatitis, highlighting significant variability across different demographics and settings.</jats:p></jats:sec>

Seborrheic dermatitis and dandruff: a comprehensive review.

J Clin Investig Dermatol

Unmet needs for patients with seborrheic dermatitis.

J Am Acad Dermatol

Seborrheic dermatitis in older adults: pathogenesis and treatment options.

Drugs Aging

Seborrheic dermatitis: etiology, risk factors, and treatments: facts and controversies.

Clin Dermatol

Interventions for infantile seborrhoeic dermatitis (including cradle cap).

Cochrane Database Syst Rev

Quality of life assessment of patients with scalp dermatitis using the Italian version of the Scalpdex.

Acta Derm Venereol

Perfil clínico, terapéutico y calidad de vida de los pacientes con dermatitis seborreica.

Actas Dermosifiliogr

Quality of life in patients suffering from seborrheic dermatitis: influence of age, gender and education level.

Mycoses

Clinical characteristics and quality of life in seborrheic dermatitis patients: a cross-sectional study in China.

Health Qual Life Outcomes

Seborrheic dermatitis—looking beyond Malassezia.

Exp Dermatol

Prevalence survey of dermatological conditions in mountainous North India.

Int J Dermatol

Study of the skin disease spectrum occurring in an Afro-Caribbean population.

A cross-sectional study on dermatological diseases among male prisoners in southern Lazio, Italy.

Dermatological diseases in the elderly: an observational study at a tertiary care hospital in northern India.

Natl Med J India

Prevalence and pattern of dermatological disorders in the pediatric emergency service.

J Dermatol Dermatol Surg

Survey of common cutaneous lesions in healthy infants at the well baby clinic.

J Med Assoc Thai

Meta-analysis of observational studies in epidemiology: a proposal for reporting.

JAMA

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.

Pattern changes of cutaneous dermatoses among Iraqi women preceding and during the COVID-19 pandemic.

F1000Res

Itchy dermatoses in Iraqi children: a single hospital experience.

Prevalence and pattern of skin disorders among female schoolchildren in Eastern Saudi Arabia.

Saudi Med J

The pattern of skin and venereal disorders among patients attending in the OPD of dermatology and venereology department of a tertiary care private hospital, Dhaka, Bangladesh.

J Pak Assoc Dermatol

The prevalence of skin and venereal diseases among the geriatric patients attending in a tertiary care hospital in Dhaka, Bangladesh.

Bangladesh J Med Sci

Prevalence of skin diseases in Jordanian children.

Rawal Med J

Occupational facial dermatoses related to mask use in healthcare professionals.

J Cosmet Dermatol

Pattern of skin diseases among patients attending a tertiary care hospital in Lahore, Pakistan.

J Taibah Univ Med Sci

Pattern of skin diseases at Bahawal Victoria Hospital, Bahawalpur.

Pakistan J Med Heal Sci

Teledermatology management of difficult-to-treat dermatoses in the Faroe Islands.

Acta Dermatovenerologica Alpina

Prevalence of common skin diseases and their associated factors among military personnel in Korea: a cross-sectional study.

J Korean Med Sci

Pattern of skin disorders among adolescent female students at Hyderabad, Sindh.

Pattern of pediatric dermatoses in a tertiary care centre of South West Rajasthan.

Indian J Dermatol

Dermatologic emergencies in a tertiary hospital: A descriptive study.

Prevalence and related factors of psoriasis and seborrheic dermatitis: a community-based study.

Turk J Med Sci

A survey of skin problems and skin care regimens in the elderly.

Arch Dermatol

Profile of patients admitted to a triage dermatology clinic at a tertiary hospital in Sao Paulo, Brazil.

An Bras Dermatol

Prevalence of skin diseases in a dermatology outpatient clinic in Turkey: a cross-sectional, retrospective study.

J Dermatol Case Rep

The spectrum of skin diseases in a rural setting in Cameroon (sub-Saharan Africa).

BMC Dermatol

Prevalence of skin disease in urban Haiti: a cross-sectional study.

Dermatology

Epidemiology of frequently occurring skin diseases in Italian children from 2006 to 2012: a retrospective, population-based study.

Pediatr Dermatol

The relationship of acne with dandruff and seborrhoeic dermatitis.

Br J Dermatol Syph

Prevalence of dermatoses in dermatologic evaluation requests from patients admitted to a tertiary hospital for 10 years.

Scalp seborrheic dermatitis: prevalence and associated factors in male adolescents.

A study of skin disease spectrum occurring in Angola phototype V-VI population in Luanda.

Common dermatoses in children referred to a specialized pediatric dermatology service in Mexico: a comparative study between two decades.

ISRN Dermatol

Profile of skin disorders in unreached hilly areas of North India.

Dermatol Res Pract

The spectrum of skin diseases in a black population in Durban, KwaZulu-Natal, South Africa.

Prevalence of skin diseases treated at public referral hospitals in KwaZulu-Natal, South Africa.

Br J Dermatol

The spectrum of skin diseases seen in a Jamaican tertiary academic medical center.

JAAD Int

The spectrum of paediatric dermatoses in a university hospital in Cairo, Egypt.

J Eur Acad Dermatol Venereol

Prevalences of skin diseases among primary schoolchildren in Damietta, Egypt.

Evaluation of dermatological consultations of patients treated in intensive care unit.

Prevalence of cutaneous findings in hospitalized neonates: a prospective observational study.

Prevalence of dermatological disorders in Japan: a nationwide, cross-sectional, seasonal, multicenter, hospital-based study.

J Dermatol

Pattern of papulosquamous disorders in children: a clinico-epidemiological study.

Cureus

Relation of sociodemographics and personal hygiene on different childhood dermatoses.

Kathmandu Univ Med J (KUMJ)

Utilization pattern of dermatological procedures for skin disorders in a tertiary care hospital, Telangana.

Int J Toxicol Pharmacol Res.

Epidemiology of skin disease among children in a referral skin clinic in Singapore.

Pediatric skin disorders encountered in a dermatology outpatient clinic in Turkey.

Incidence of common dermatoses in a predominantly Black dermatologic practice.

Cutis

Dermatological disorders in Johannesburg, South Africa.

Clin Exp Dermatol

Novel trends in cutaneous manifestations of geriatric dermatoses in a tertiary care hospital, South India.

Pattern of pediatric dermatoses in Kashmir valley: a study from a tertiary care center.

Indian J Dermatol Venereol Leprol

Dermatologic conditions in teenage adolescents in Nigeria.

Adolesc Health Med Ther

Most common pediatric skin conditions managed in outpatient dermatology clinics in the United States stratified by race and ethnicity.

Prevalence of skin conditions in primary school children in Turkey: differences based on socioeconomic factors.

Poor agreement between self-reported and dermatologists’ diagnoses for five common dermatoses.

Skin conditions and related need for medical care among persons 1-74 years—United States, 1971-1974.

Vital Health Stat 11

Focus on the top ten diagnoses could reduce pediatric dermatology referrals.

Scalp dermatoses: the patterns and impact on quality of life.

Age and sex prevalence of infectious dermatoses among primary school children in a rural South-Eastern Nigerian community.

Pan Afr Med J

The prevalence of paediatric skin conditions at a dermatology clinic in Kwazulu-Natal province over a 3-month period.

SAJCH South African J Child Heal.

Skin diseases in Greek and immigrant children in Athens.

Can outpatient department of a tertiary care hospital provide an insight into the prevalence of commonest dermatoses.

J Med Sci.

Seasonal and gender variation in skin disease: a cross-sectional study of 3120 patients at Razi hospital.

Int J Womens Dermatol

Referral pattern of skin diseases in an acute outpatient dermatological clinic in Copenhagen.

Skin diseases in pediatric patients attending a tertiary dermatology hospital in Northern Tanzania: a cross-sectional study.

Prevalence of skin diseases in female prisoners in Turkey: analysis of impact of prison conditions and psychological stress.

Acta Dermatovenerol Croat

Dermatoses in the early neonatal period: their association with neonatal, obstetric and demographic variables.

Rev Paul Pediatr

Prevalence and associated factors of skin diseases among geriatric outpatients from a metropolitan dermatologic clinic in Thailand.

Dermatologica Sin.

Prevalence of hair disorders and their related factors among adolescent students in public boarding school, West Java, Indonesia.

Pakistan Paediatr J

Prevalence of skin diseases in a population. a census study from the Faroe Islands.

Dan Med Bull

Social isolation: main dermatosis and the impact of stress during the COVID-19 pandemic.

Einstein (Sao Paulo)

The burden of co-existing dermatological disorders and their tendency of being overlooked among patients admitted to Muhimbili National Hospital in Dar es Salaam, Tanzania.

High prevalence of seborrhoeic dermatitis on the face and scalp in mountain guides.

Prevalence and pattern of paediatric dermatoses among children in Aminu Kano teaching Hospital Kano, Nigeria.

Acta Biomed

Pattern of skin diseases at The Children’s Hospital, Lahore: comparison between 1996-1998 and 2011.

Survey of cutaneous lesions in Indian newborns.

Dermatological diseases in palliative care patients: a prospective study of 271 patients.

J Ger Soc Dermatol

Pattern of skin diseases in the Central Iran, Yazd Province.

The pattern of skin disorders in federal prison population.

Klin dermatologiya i Venerol

Prevalence of skin diseases in Ibadan, Nigeria.

Prevalence of skin disorders in school children in Southwest Nigeria.

Int J Adolesc Med Health

Pattern of dermatoses among inmates of Ilesha Prison, Nigeria.

Niger Postgrad Med J

Cutaneous disorders of adolescence among Nigerian secondary school students.

Seborrheic dermatitis: lifetime detection rates.

Dermatologist-diagnosed skin diseases among immigrant Latino poultry processors and other manual workers in North Carolina, USA.

The frequency of common nonmalignant skin conditions in adults in central Victoria, Australia.

Clinicoepidemiology of skin diseases in children seen at the university hospital center Morafeno, Toamasina, Madagascar.

The incidence of skin diseases in the west of Scotland.

Prevalence and characterization of neonatal skin disorders in the first 72h of life.

J Pediatr (Rio J)

Seborrheic dermatitis is a prevalent chronic inflammatory skin disease, yet its global prevalence, pathogenesis, and epidemiology remain inadequately defined.
To provide a detailed estimation of the global prevalence of seborrheic dermatitis, analyze demographic variations, and explore differences in various settings.
Embase, PubMed, Scopus, and Cochrane Database of Systematic Reviews were searched from inception through October 2023.
Original investigations on seborrheic dermatitis prevalence were included after duplicate screening of titles, abstracts, and full articles, including only studies with clinician-diagnosed cases.
Following PRISMA guidelines, data were extracted and quality was assessed independently by multiple reviewers. A random-effects model using restricted maximum likelihood was used for meta-analysis and subgroup analyses.
The primary outcome was the pooled estimate of global seborrheic dermatitis prevalence.
From 1574 identified articles, 121 studies were included, encompassing 1 260 163 individuals and revealing a pooled global seborrheic dermatitis prevalence of 4.38% (95% CI, 3.58%-5.17%), with significant heterogeneity (I2 = 99.94%). Subgroup analyses showed variations by age, with a higher prevalence in adults (5.64% [95% CI, 4.01%-7.27%]) compared to children (3.70% [95% CI, 2.69%-4.80%]) and neonates (0.23% [95% CI, 0.04%-0.43%]). Geographic analyses indicated variability, with the highest prevalence in South Africa (8.82% [95% CI, 3.00%-14.64%]) and the lowest in India (2.62% [95% CI, 1.33%-3.92%]).
This comprehensive meta-analysis provides a detailed estimation of the global prevalence of seborrheic dermatitis, highlighting significant variability across different demographics and settings.

The Global Prevalence of Seborrheic Dermatitis: A Systematic Review and Meta-Analysis.

The Global Prevalence of Seborrheic Dermatitis

Papers