2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:T6c4,Menopause, marked by hormonal decline and menstrual cessation, is associated with various symptoms. Socio-demographic and behavioural factors may influence symptom type and severity. Understanding these associations can inform better symptom management. To identify factors associated with the presence and severity of menopausal symptoms through systematic review and meta-analysis. We searched Medline, Embase, CINAHL and Cochrane for studies on demographic, behavioural, or health factors linked to vasomotor, vaginal dryness and joint symptoms in women aged 40-60. Studies reporting odds ratios or raw numbers for symptom presence or severity were included. Studies were combined for meta-analysis, reporting odds ratios and 95% confidence intervals. Quality assessment was performed to quantify the risk of bias. Of 9228 screened articles, 61 were meta-analysed. Compared with White women, Black women had higher odds of vasomotor symptom presence (OR 1.65, 1.41-1.94) and severity (OR 1.91, 1.10-3.29), and vaginal dryness presence (OR 1.27, 1.10-1.47), while Asian had lower vasomotor symptom presence and severity (OR 0.40, 0.22-0.72; OR 0.55, 0.53-0.56). Higher education (OR 1.31, 1.09-1.56), high income (OR 1.41, 1.01-1.97) and depression (OR 2.36, 1.51-3.70) were associated with increased presence of vasomotor symptoms. Smoking and obesity were associated with both presence (OR 1.63, 1.30-2.04 and 1.35, 1.02-1.78) and severity (OR 1.56, 1.07-2.27 and 1.42, 1.11-1.83) of vasomotor symptoms. Socio-demographic and behavioural factors, including ethnicity, education, income, smoking, obesity and depression, influence menopausal symptoms, highlighting the need for personalised care. PROSPERO number: CRD42023459154.31:Tbed,ABSTRACT Background Menopause, marked by hormonal decline and menstrual cessation, is associated with various symptoms. Socio‐demographic and behavioural factors may influence symptom type and severity. Understanding these associations can inform better symptom management. Objectives To identify factors associated with the presence and severity of menopausal symptoms through systematic review and meta‐analysis. Search Strategy We searched Medline, Embase, CINAHL and Cochrane for studies on demographic, behavioural, or health factors linked to vasomotor, vaginal dryness and joint symptoms in women aged 40–60. Selection Criteria Studies reporting odds ratios or raw numbers for symptom presence or severity were included. Data Collection and Analysis Studies were combined for meta‐analysis, reporting odds ratios and 95% confidence intervals. Quality assessment was performed to quantify the risk of bias. Results Of 9228 screened articles, 61 were meta‐analysed. Compared with White women, Black women had higher odds of vasomotor symptom presence (OR 1.65, 1.41–1.94) and severity (OR 1.91, 1.10–3.29), and vaginal dryness presence (OR 1.27, 1.10–1.47), while Asian had lower vasomotor symptom presence and severity (OR 0.40, 0.22–0.72; OR 0.55, 0.53–0.56). Higher education (OR 1.31, 1.09–1.56), high income (OR 1.41, 1.01–1.97) and depression (OR 2.36, 1.51–3.70) were associated with increased presence of vasomotor symptoms. Smoking and obesity were associated with both presence (OR 1.63, 1.30–2.04 and 1.35, 1.02–1.78) and severity (OR 1.56, 1.07–2.27 and 1.42, 1.11–1.83) of vasomotor symptoms. Conclusion Socio‐demographic and behavioural factors, including ethnicity, education, income, smoking, obesity and depression, influence menopausal symptoms, highlighting the need for personalised care. Trial Registration PROSPERO number: CRD42023459154 25:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Vaginal Dryness: condition Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Vaginal Dryness (condition). Clinician-written summaries and actionable practice insights. 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Compared with White women, Black women had higher odds of vasomotor symptom presence (OR 1.65, 1.41-1.94) and severity (OR 1.91, 1.10-3.29), and vaginal dryness presence (OR 1.27, 1.10-1.47), while Asian had lower vasomotor symptom presence and severity (OR 0.40, 0.22-0.72; OR 0.55, 0.53-0.56). Higher education (OR 1.31, 1.09-1.56), high income (OR 1.41, 1.01-1.97) and depression (OR 2.36, 1.51-3.70) were associated with increased presence of vasomotor symptoms. Smoking and obesity were associated with both presence (OR 1.63, 1.30-2.04 and 1.35, 1.02-1.78) and severity (OR 1.56, 1.07-2.27 and 1.42, 1.11-1.83) of vasomotor symptoms.","abstract":"$30","keywords":["disparities","menopause","meta‐analysis","symptoms","systematic review"],"pubmed_id":"42087841","conclusions":"Socio-demographic and behavioural factors, including ethnicity, education, income, smoking, obesity and depression, influence menopausal symptoms, highlighting the need for personalised 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L.","volume":"31","first-page":"258","unstructured":null,"article-title":"Improving Access to Smoking Cessation Services for Disadvantaged Groups: A Systematic Review","journal-title":"Journal of Public Health","doi-asserted-by":"crossref"},{"DOI":null,"key":"e_1_2_11_119_1","year":"2025","issue":null,"author":"Australasian Menopause Society","volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":null},{"DOI":"10.1136/bmj.r2038","key":"e_1_2_11_120_1","year":"2025","issue":null,"author":"Hirst J.","volume":"390","first-page":null,"unstructured":null,"article-title":"Menopause Care Is Neglected and Inequitable","journal-title":"BMJ","doi-asserted-by":"crossref"},{"DOI":"10.3399/BJGP.2024.0781","key":"e_1_2_11_121_1","year":"2025","issue":null,"author":"Eccles A.","volume":"75","first-page":"e816","unstructured":null,"article-title":"Accessing Equitable Menopause Care in the Contemporary NHS‐Women's Experiences","journal-title":"British Journal of General Practice: The Journal of the Royal College of General Practitioners","doi-asserted-by":"crossref"}],"short-title":[],"update-policy":"https://doi.org/10.1002/crossmark_policy","alternative-id":["10.1111/1471-0528.70257"],"article-number":"1471-0528.70257","content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"original-title":[],"container-title":["BJOG: An International Journal of Obstetrics & Gynaecology"],"reference-count":120,"published-online":{"date-time":null,"timestamp":null,"date-parts":[[2026,5,6]]},"references-count":120,"short-container-title":["BJOG"],"is-referenced-by-count":0},"unpaywall":{"doi":"10.1111/1471-0528.70257","is_oa":true,"title":"Factors Associated With Menopause Symptoms: A Systematic Review and Meta‐Analysis","updated":"2026-05-07T14:04:23+00:00","published_date":"2026-05-06","best_oa_location":{"url":"https://doi.org/10.1111/1471-0528.70257","pmh_id":null,"url_for_pdf":null,"url_for_landing_page":"https://doi.org/10.1111/1471-0528.70257"}}},"created_at":"2026-05-13T13:19:33.086Z","updated_at":"2026-05-14T15:13:26.918Z","tags":[{"paper_doi":"10.1111/1471-0528.70257","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"category","value":"Obstetrics & Gynecology","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"condition","value":"Menopausal Symptoms","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"condition","value":"Vaginal Dryness","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"condition","value":"Vasomotor Symptoms","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"impact_flag","value":"practice_changing","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"level_of_evidence","value":"1","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"sample_size","value":"n=61","value_numeric":61},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"study_design","value":"Systematic Review and Meta-Analysis","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"warning","value":"Joint symptoms were listed as an outcome of interest but results for this domain were not reported in the abstract; conclusions may be incomplete for that symptom category.","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"warning","value":"Sample size tag reflects number of studies meta-analysed (n=61), not individual participants — total participant count across studies was not reported in the abstract.","value_numeric":null},{"paper_doi":"10.1111/1471-0528.70257","tag_type":"warning","value":"The 'practice_changing' impact flag is applied cautiously — findings confirm and quantify known associations but introduce new specificity (e.g., depression OR 2.36) that may shift clinical prioritisation.","value_numeric":null}],"summaries":{"what_studied":"This systematic review and meta-analysis examined socio-demographic and behavioural factors (ethnicity, education, income, smoking, obesity, depression) associated with the presence and severity of vasomotor, vaginal dryness, and joint symptoms in women aged 40–60, drawing from 61 studies identified across Medline, Embase, CINAHL, and Cochrane.","key_result":"Black women had higher odds of vasomotor symptoms vs. White women (presence OR 1.65; severity OR 1.91), while Asian women had lower odds (presence OR 0.40; severity OR 0.55). Depression carried the strongest association with vasomotor symptom presence (OR 2.36). Smoking and obesity each independently raised odds of both vasomotor symptom presence and severity (smoking: OR 1.63 presence, 1.56 severity; obesity: OR 1.35 presence, 1.42 severity).","limitations":"- Risk of bias across included studies was not fully mitigated, and heterogeneity between study populations likely affects pooled estimates.\n- Data on joint symptoms were insufficient for robust meta-analysis conclusions.\n- Causal direction cannot be established from observational study designs.","practice_takeaway":"Screen menopausal women for depression, smoking, and obesity — all are modifiable factors tied to worse vasomotor symptoms. Tailor counselling to ethnicity and socioeconomic background, as these strongly shape symptom burden and should guide personalised menopause care."}}],"initialOffset":1,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"condition","value":"Vaginal Dryness"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Conditions","href":"/hub/tag/condition"},{"name":"Vaginal Dryness"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"condition","hub_tag_value":"Vaginal Dryness"}}}]]

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