2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:T73e,This year in review (1) narratively synthesises the effect of, or patient experience with, non-pharmacological or non-surgical rehabilitation treatments for osteoarthritis at any joint; and (2) describes how sex and/or gender are defined, reported, and analysed. We searched three databases (Medline, Embase, CINAHL) for studies that met predefined criteria and selected those of perceived moderate-to-high quality and importance published between 12th March 2024 and 1st March 2025. Studies were grouped according to predominant treatment topic areas (e.g. core [exercise, diet]; adjunct [electrotherapy, manual therapy]; multimodal [different rehabilitation treatments]). Two authors independently screened records. One author extracted data, and another checked 10% of the accuracy. Full-text screening identified 158 eligible studies, reduced to 39 for synthesis. We identified eight themes: i) Exercise is effective for knee osteoarthritis and comorbidities, but has varied effects for hip osteoarthritis; ii) Diet plus exercise is effective for weight loss, but may not reduce pain; iii) Digital rehabilitation is a viable alternative to in-person care; iv) No added benefit of mind/behavioural treatments; v) Effects of electrotherapy modalities on pain were inconsistent and region-specific; vi) Orthoses may relieve pain, but should be individualised to patient preferences; vii) Acupuncture and blood flow restriction treatment show effectiveness in single clinical trials; viii) Treatment packages for osteoarthritis have varied benefits. Sex and gender were reported in 23 and 11 studies, respectively. For gender, most studies used female/male/woman/man interchangeably. No study defined sex or gender, 5% reported results disaggregated by sex or gender, no study justified why results were not, and 5% summarised key sex or gender findings.31:T441,Individuals in the 2 conditions (n = 268; 241 [89.9%] women; mean [SD] age, 36.8 [11.1] years; skin picking, 68.3%; trichotillomania, 28.4%; nail biting, 36.6%; lip-cheek biting, 26.1%; other, 20.1%) did not differ on any baseline characteristics. The experimental group significantly improved on the primary outcome (GBS-45) for both the per-protocol (technique was used at least once weekly, ηp2 = 0.068, P = .001) and the intention-to-treat analyses relative to the wait-list control group (expectation-maximization algorithm; ηp2 = 0.019, P = .02). The interaction of group and time yielded statistical trends in favor of the experimental condition only on the Patient Health Questionnaire-9 and quality of life. For the Clinical Global Impressions scale, more individuals in the habit replacement group reported improvement (52.8% vs 19.6%; P < .001). User satisfaction in the habit replacement group was high. Moderation analyses that included all baseline variables showed that those who exhibited nail biting particularly benefited from the new technique.32:T99e,Body-focused repetitive behaviors (BFRBs; eg, skin picking) encompass a set of conditions at the interface of dermatology and psychiatry/psychology. The disorder is prevalent but currently underdiagnosed and undertreated. To compare a new self-help intervention, habit replacement, against a wait-list control condition for the treatment of BFRBs. This randomized clinical trial was conducted online in 2022. Participants were a population-based nonclinical sample with BFRBs and were recruited via social media. Initially, 481 individuals entered the assessment; 213 were excluded blind to results. A final sample of 268 participants were randomized. The intervention period was 6 weeks. Participants were randomized to a self-help intervention, habit replacement, or a wait-list control condition (each n = 134). The Generic BFRB Scale-45 (GBS-45, self-report) represented the primary outcome. Individuals in the 2 conditions (n = 268; 241 [89.9%] women; mean [SD] age, 36.8 [11.1] years; skin picking, 68.3%; trichotillomania, 28.4%; nail biting, 36.6%; lip-cheek biting, 26.1%; other, 20.1%) did not differ on any baseline characteristics. The experimental group significantly improved on the primary outcome (GBS-45) for both the per-protocol (technique was used at least once weekly, ηp2 = 0.068, P = .001) and the intention-to-treat analyses relative to the wait-list control group (expectation-maximization algorithm; ηp2 = 0.019, P = .02). The interaction of group and time yielded statistical trends in favor of the experimental condition only on the Patient Health Questionnaire-9 and quality of life. For the Clinical Global Impressions scale, more individuals in the habit replacement group reported improvement (52.8% vs 19.6%; P < .001). User satisfaction in the habit replacement group was high. Moderation analyses that included all baseline variables showed that those who exhibited nail biting particularly benefited from the new technique. The present proof-of-concept randomized clinical trial tentatively demonstrates that habit replacement is a feasible and effective self-help strategy against BFRBs, especially for nail biting. Study limitations include the lack of external assessment and verified diagnoses. In addition, the study is missing follow-up data. Self-help habit replacement shows promise in reducing BFRBs but not concomitant symptoms. German Clinical Trials Register Identifier: DRKS00030511.33:Td65,ImportanceBody-focused repetitive behaviors (BFRBs; eg, skin picking) encompass a set of conditions at the interface of dermatology and psychiatry/psychology. The disorder is prevalent but currently underdiagnosed and undertreated.ObjectiveTo compare a new self-help intervention, habit replacement, against a wait-list control condition for the treatment of BFRBs.Design, Setting, and ParticipantsThis randomized clinical trial was conducted online in 2022. Participants were a population-based nonclinical sample with BFRBs and were recruited via social media. Initially, 481 individuals entered the assessment; 213 were excluded blind to results. A final sample of 268 participants were randomized. The intervention period was 6 weeks.InterventionsParticipants were randomized to a self-help intervention, habit replacement, or a wait-list control condition (each n = 134).Main Outcomes and MeasuresThe Generic BFRB Scale-45 (GBS-45, self-report) represented the primary outcome.ResultsIndividuals in the 2 conditions (n = 268; 241 [89.9%] women; mean [SD] age, 36.8 [11.1] years; skin picking, 68.3%; trichotillomania, 28.4%; nail biting, 36.6%; lip-cheek biting, 26.1%; other, 20.1%) did not differ on any baseline characteristics. The experimental group significantly improved on the primary outcome (GBS-45) for both the per-protocol (technique was used at least once weekly, ηp2 = 0.068, P = .001) and the intention-to-treat analyses relative to the wait-list control group (expectation–maximization algorithm; ηp2 = 0.019, P = .02). The interaction of group and time yielded statistical trends in favor of the experimental condition only on the Patient Health Questionnaire-9 and quality of life. For the Clinical Global Impressions scale, more individuals in the habit replacement group reported improvement (52.8% vs 19.6%; P &lt; .001). User satisfaction in the habit replacement group was high. Moderation analyses that included all baseline variables showed that those who exhibited nail biting particularly benefited from the new technique.Conclusions and RelevanceThe present proof-of-concept randomized clinical trial tentatively demonstrates that habit replacement is a feasible and effective self-help strategy against BFRBs, especially for nail biting. Study limitations include the lack of external assessment and verified diagnoses. In addition, the study is missing follow-up data. Self-help habit replacement shows promise in reducing BFRBs but not concomitant symptoms.Trial RegistrationGerman Clinical Trials Register Identifier: DRKS0003051125:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Behavioral Therapy: modality Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Behavioral Therapy (modality). Clinician-written summaries and actionable practice insights. 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Selection bias is likely—patients who were medically and financially stable were more able to participate in therapy.","practice_takeaway":"Offer bAUDT early in liver transplant evaluation for ALD patients with early sobriety, as participation is linked to higher waitlisting rates. Prioritize reducing access barriers (insurance gaps, inpatient status, older age) since those most in need are least likely to receive therapy.","what_studied":"This multicenter retrospective cohort study (RESOLVE-ALD) evaluated whether participation in behavioral alcohol use disorder therapy (bAUDT) during liver transplant evaluation (LTE) affected waitlisting rates and return to alcohol use in 545 adults with alcohol-associated liver disease (ALD) and <6 months of sobriety, across 6 U.S. centers (2018–2021).","key_result":"Only 22.4% of patients participated in bAUDT during LTE; participation tripled the adjusted odds of waitlisting (aOR=3.40, p=0.006), but did not significantly predict return to alcohol use pre- or post-transplant. Older age, underinsurance, and inpatient evaluation status each roughly halved the odds of receiving bAUDT."}},{"doi":"10.1016/j.cgh.2026.03.047","pmid":"42484589","title":"Singing Therapy versus Diaphragmatic Breathing for Supragastric Belching: A Multicenter Randomized Controlled Trial","journal_title":"Clinical Gastroenterology and Hepatology","journal_issn":"1542-3565","published_at":"2026-07-22T00:00:00.000Z","url":"https://doi.org/10.1016/j.cgh.2026.03.047","source_score":72,"is_retracted":false,"is_open_access":false,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-07-29T13:31:10.376Z","updated_at":"2026-07-29T13:31:10.376Z","tags":[{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"category","value":"Gastroenterology & Hepatology","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"condition","value":"Supragastric Belching","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"impact_flag","value":"practice_changing","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"level_of_evidence","value":"2","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"modality","value":"Behavioral Therapy","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"modality","value":"Breathing Therapy","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"sample_size","value":"n=72","value_numeric":72},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"sex","value":"mixed","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"study_design","value":"Randomized Controlled Trial","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"warning","value":"No pharmacological interventions were included; the study does not address whether singing therapy adds benefit on top of medical treatment.","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"warning","value":"The impact_flag 'practice_changing' is applied cautiously—the trial is small (n=72) and single-country; replication in larger, more diverse populations is needed before widespread adoption.","value_numeric":null},{"paper_doi":"10.1016/j.cgh.2026.03.047","tag_type":"warning","value":"The paper is published in 2026 and registered at a Chinese trial registry; international guideline uptake is likely pending external validation.","value_numeric":null}],"summaries":{"what_studied":"This RCT compared 1 week of structured singing therapy vs. diaphragmatic breathing in 72 adults with Rome IV–diagnosed supragastric belching across 2 tertiary centers in China (Oct 2024–Apr 2025), with follow-up at 1 month.","key_result":"Singing therapy achieved a higher response rate (≥50% reduction in belching VAS) than diaphragmatic breathing both immediately post-treatment (72.2% vs 38.9%; P=.004) and at 1-month follow-up (50.0% vs 30.6%; P=.032); older age and higher baseline VAS were also independent predictors of response.","limitations":"Small sample (n=72) from 2 Chinese tertiary centers limits generalizability; open-label design makes blinding impossible; follow-up extends only to 1 month, leaving long-term durability unknown.","practice_takeaway":"For patients with supragastric belching—especially older adults with severe symptoms—singing therapy may be a more effective and engaging alternative to diaphragmatic breathing. Clinicians can consider offering it as a first-line behavioral option, particularly when patients find diaphragmatic breathing monotonous."}},{"doi":"10.3389/fnsys.2026.1812957","pmid":null,"title":"The body does not keep the score: trauma, predictive coding, and the restoration of metastability","journal_title":"Frontiers in Systems Neuroscience","journal_issn":"1662-5137","published_at":"2026-04-30T00:00:00.000Z","url":"https://doi.org/10.3389/fnsys.2026.1812957","source_score":148,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2026-05-05","doi":"10.3389/fnsys.2026.1812957","days":"14","issn":"1662-5137","rank":"6","field":"Clinical Medicine","score":"148","category":"Neurosciences","categories":["Neurosciences"],"_categories":["Neurosciences"]},"pubmed":null,"crossref":{"DOI":"10.3389/fnsys.2026.1812957","URL":"https://doi.org/10.3389/fnsys.2026.1812957","ISSN":["1662-5137"],"link":[{"URL":"https://www.frontiersin.org/articles/10.3389/fnsys.2026.1812957/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":null,"type":"journal-article","issue":null,"score":1,"title":["The body does not keep the score: trauma, predictive coding, and the restoration of metastability"],"author":[{"given":"Steven","family":"Kotler","sequence":"first","affiliation":[{"name":"Florida Atlantic University"}]},{"given":"Michael","family":"Mannino","sequence":"additional","affiliation":[{"name":"Florida Atlantic University"},{"name":"Miami Dade College"}]},{"given":"Glenn","family":"Fox","sequence":"additional","affiliation":[{"name":"University of Southern California"}]},{"given":"Karl","family":"Friston","sequence":"additional","affiliation":[{"name":"University College London"}]}],"issued":{"date-parts":[[2026,4,30]]},"member":"1965","prefix":"10.3389","source":"Crossref","volume":"20","created":{"date-time":"2026-04-30T05:41:51Z","timestamp":1777527711000,"date-parts":[[2026,4,30]]},"indexed":{"date-time":"2026-05-04T03:13:57Z","timestamp":1777864437897,"date-parts":[[2026,5,4]]},"license":[{"URL":"https://creativecommons.org/licenses/by/4.0/","start":{"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000,"date-parts":[[2026,4,30]]},"delay-in-days":0,"content-version":"vor"}],"subject":[],"abstract":null,"relation":{},"resource":{"primary":{"URL":"https://www.frontiersin.org/articles/10.3389/fnsys.2026.1812957/full"}},"subtitle":[],"deposited":{"date-time":"2026-04-30T05:41:55Z","timestamp":1777527715000,"date-parts":[[2026,4,30]]},"issn-type":[{"type":"electronic","value":"1662-5137"}],"published":{"date-parts":[[2026,4,30]]},"publisher":"Frontiers Media SA","reference":[{"DOI":"10.1016/j.cortex.2022.06.005","key":"B1","year":"2022","issue":null,"author":"Alameda","volume":"154","first-page":"348","unstructured":null,"article-title":"The brain in flow: a systematic review on the neural basis of the flow state","journal-title":"Cortex","doi-asserted-by":"publisher"},{"DOI":"10.1371/journal.pcbi.1010490","key":"B2","year":"2022","issue":null,"author":"Allen","volume":"18","first-page":"e1010490","unstructured":null,"article-title":"In the body's eye: the computational anatomy of interoceptive inference","journal-title":"PLoS Comput. 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Resilience data support this: ~65.7% of trauma-exposed individuals follow a resilient trajectory without chronic PTSD (Bonanno et al., 2015, systematic review of 54 studies). A cited RCT (Walter et al., 2023; n=96 active-duty service members) found surf and hike therapy both improved depression, with surf therapy showing higher MDD remission rates at 3-month follow-up, though groups did not differ significantly immediately post-program.","limitations":"- The core claim that PTSD involves reduced metastability has **not been directly tested** using established metastability metrics (e.g., Kuramoto order parameter) in PTSD populations; the Hellyer et al. findings cited pertain to traumatic brain injury, a distinct condition.\n- The specific contribution of flow-state neurobiology cannot be isolated from confounds (exercise, nature exposure, social connection) in supporting RCT evidence.\n- Key supporting findings (e.g., reduced working memory predicting intrusive memories) come from analog, non-clinical samples and await replication in clinical PTSD.","practice_takeaway":"Clinicians should consider trauma as a failure of adaptive inference and network flexibility rather than somatic storage—this opens the door to interventions that train cognitive control (mindfulness, working memory, executive-function exercises) and may expand options to include flow-inducing activities (e.g., surf or adventure therapy). 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Searches of Medline, Embase, and CINAHL (12 Mar 2024–1 Mar 2025) found 158 eligible studies; 39 were selected for synthesis across core, adjunct, and multimodal treatments.","key_result":"Eight themes emerged: exercise helps knee osteoarthritis and comorbidities but shows mixed effects in hip osteoarthritis; diet plus exercise reduces weight but may not reduce pain; digital rehab is a viable alternative to in‑person care; mind/behavioral add‑ons showed no added benefit; electrotherapy pain effects were inconsistent and region‑specific; orthoses can relieve pain but should reflect patient preferences; acupuncture and blood flow restriction each showed effectiveness in single trials; multimodal packages had varied benefits. Sex was reported in 23 studies and gender in 11; no study defined sex or gender, 5% disaggregated results by sex/gender, no study justified the lack of disaggregation, and 5% summarized key sex/gender findings.","limitations":"Narrative selection of a subset (39/158) judged moderate-to-high quality may introduce selection bias; conclusions span heterogeneous joints, interventions, and outcomes with region‑specific and inconsistent effects; some signals rely on single clinical trials.","practice_takeaway":"Prioritize exercise for knee osteoarthritis and consider digital rehab as a practical alternative; use diet plus exercise for weight loss without promising pain relief. Reserve mind/behavioral add‑ons and electrotherapy given uncertain benefit, individualize orthoses to patient preference, and treat acupuncture and blood flow restriction as preliminary signals; expect little sex- or gender‑specific guidance due to poor reporting."}},{"doi":"10.1001/jamadermatol.2023.2167","pmid":"37466986","title":"Self-Help Habit Replacement in Individuals With Body-Focused Repetitive Behaviors","journal_title":"JAMA Dermatology","journal_issn":"2168-6068","published_at":"2023-07-19T00:00:00.000Z","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10357355","source_score":498,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2023-09-25","doi":"10.1001/jamadermatol.2023.2167","days":"30","issn":"2168-6068","rank":"3","field":"Clinical Medicine","score":"498","category":"Dermatology","categories":["Dermatology"],"_categories":["Dermatology"]},"pubmed":{"doi":"10.1001/jamadermatol.2023.2167","title":"Self-Help Habit Replacement in Individuals With Body-Focused Repetitive Behaviors: A Proof-of-Concept Randomized Clinical Trial.","journal":"JAMA dermatology","methods":"","results":"$31","abstract":"$32","keywords":[],"pubmed_id":"37466986","conclusions":"","publication_date":"2023-07-19T00:00:00"},"crossref":{"DOI":"10.1001/jamadermatol.2023.2167","URL":"https://doi.org/10.1001/jamadermatol.2023.2167","ISSN":["2168-6068"],"link":[{"URL":"https://jamanetwork.com/journals/jamadermatology/articlepdf/2807394/jamadermatology_moritz_2023_br_230011_1695075748.87901.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":"992","type":"journal-article","issue":"9","score":1,"title":["Self-Help Habit Replacement in Individuals With Body-Focused Repetitive Behaviors"],"author":[{"given":"Steffen","family":"Moritz","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany"}]},{"given":"Danielle","family":"Penney","sequence":"additional","affiliation":[{"name":"Centre Intégré Universitaire de Santé et de Services Sociaux de l’Ouest-de-l’Île-de-Montréal Douglas Mental Health University Institute, Verdun, Quebec, Canada"}]},{"given":"Franziska","family":"Missmann","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany"}]},{"given":"Sarah","family":"Weidinger","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany"}]},{"given":"Stella","family":"Schmotz","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany"}]}],"issued":{"date-parts":[[2023,9,1]]},"member":"10","prefix":"10.1001","source":"Crossref","volume":"159","created":{"date-time":"2023-07-19T15:16:01Z","timestamp":1689779761000,"date-parts":[[2023,7,19]]},"indexed":{"date-time":"2025-09-17T15:17:01Z","timestamp":1758122221559,"date-parts":[[2025,9,17]]},"subject":[],"abstract":"$33","language":"en","relation":{},"resource":{"primary":{"URL":"https://jamanetwork.com/journals/jamadermatology/fullarticle/2807394"}},"subtitle":["A Proof-of-Concept Randomized Clinical Trial"],"deposited":{"date-time":"2023-09-20T15:16:24Z","timestamp":1695222984000,"date-parts":[[2023,9,20]]},"issn-type":[{"type":"print","value":"2168-6068"}],"published":{"date-parts":[[2023,9,1]]},"publisher":"American Medical Association (AMA)","reference":[{"DOI":"10.12659/AJCR.889357","key":"dbr230011r1","year":"2013","issue":null,"author":"Kim","volume":"14","first-page":"284","unstructured":null,"article-title":"A near fatal case of pathological skin picking.","journal-title":"Am J Case Rep","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.psychres.2023.115120","key":"dbr230011r5","year":"2023","issue":null,"author":"Lin","volume":"322","first-page":null,"unstructured":null,"article-title":"Characteristics of trichotillomania and excoriation disorder across the lifespan.","journal-title":"Psychiatry Res","doi-asserted-by":"publisher"},{"DOI":"10.1177/0145445511409395","key":"dbr230011r6","year":"2011","issue":"5","author":"Moritz","volume":"35","first-page":"468","unstructured":null,"article-title":"A randomized controlled trial of a novel self-help technique for impulse control disorders: a study on nail-biting.","journal-title":"Behav Modif","doi-asserted-by":"publisher"},{"DOI":"10.1007/s10608-022-10334-9","key":"dbr230011r7","year":"2023","issue":"1","author":"Moritz","volume":"47","first-page":"109","unstructured":null,"article-title":"Habit reversal training and variants of decoupling for use in body-focused repetitive behaviors: a randomized controlled trial.","journal-title":"Cognit Ther Res","doi-asserted-by":"publisher"},{"DOI":"10.1159/000431290","key":"dbr230011r8","year":"2015","issue":"6","author":"Weidt","volume":"84","first-page":"359","unstructured":null,"article-title":"Internet-based self-help for trichotillomania: a randomized controlled study comparing decoupling and progressive muscle relaxation.","journal-title":"Psychother Psychosom","doi-asserted-by":"publisher"},{"DOI":"10.1901/jaba.2001.34-517","key":"dbr230011r9","year":"2001","issue":"4","author":"Twohig","volume":"34","first-page":"517","unstructured":null,"article-title":"Evaluating the duration of the competing response in habit reversal: a parametric analysis.","journal-title":"J Appl Behav Anal","doi-asserted-by":"publisher"},{"DOI":"10.1016/0005-7916(85)90063-1","key":"dbr230011r10","year":"1985","issue":"3","author":"Miltenberger","volume":"16","first-page":"195","unstructured":null,"article-title":"A comparison of contingent vs non-contingent competing response practice in the treatment of nervous habits.","journal-title":"J Behav Ther Exp Psychiatry","doi-asserted-by":"publisher"},{"DOI":"10.1111/ijd.2010.49.issue-7","key":"dbr230011r11","year":"2010","issue":"7","author":"Jafferany","volume":"49","first-page":"784","unstructured":null,"article-title":"The knowledge, awareness, and practice patterns of dermatologists toward psychocutaneous disorders: results of a survey study.","journal-title":"Int J Dermatol","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.psychres.2018.10.002","key":"dbr230011r12","year":"2018","issue":null,"author":"Houghton","volume":"270","first-page":"389","unstructured":null,"article-title":"Body-focused repetitive behaviors: more prevalent than once thought?","journal-title":"Psychiatry Res","doi-asserted-by":"publisher"},{"DOI":"10.1017/S1352465822000327","key":"dbr230011r13","year":"2022","issue":"6","author":"Moritz","volume":"50","first-page":"620","unstructured":null,"article-title":"The Generic BFRB Scale-8 (GBS-8): a transdiagnostic scale to measure the severity of body-focused repetitive behaviours.","journal-title":"Behav Cogn Psychother","doi-asserted-by":"publisher"},{"DOI":"10.1001/jamanetworkopen.2022.1967","key":"dbr230011r14","year":"2022","issue":"3","author":"Lundström","volume":"5","first-page":null,"unstructured":null,"article-title":"Effect of internet-based vs face-to-face cognitive behavioral therapy for adults with obsessive-compulsive disorder: a randomized clinical trial.","journal-title":"JAMA Netw Open","doi-asserted-by":"publisher"},{"DOI":"10.1001/jamapsychiatry.2020.4364","key":"dbr230011r15","year":"2021","issue":"4","author":"Karyotaki","volume":"78","first-page":"361","unstructured":null,"article-title":"Internet-based cognitive behavioral therapy for depression: a systematic review and individual patient data network meta-analysis.","journal-title":"JAMA Psychiatry","doi-asserted-by":"publisher"},{"DOI":"10.4324/9781003299097","key":"dbr230011r2","year":"2022","issue":null,"author":"Nakell","volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"crossref"},{"DOI":null,"key":"dbr230011r3","year":"2019","issue":null,"author":"Mansueto","volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":null},{"DOI":null,"key":"dbr230011r4","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":"TLC Foundation. Expert consensus treatment guidelines: body-focused repetitive behaviors: hair pulling, skin picking, and related disorders. Published 2016. Accessed June 12, 2023. https://global-uploads.webflow.com/626958af73c43200cd878b35/62f551b797e279202e49d315_Expert_Consensus_Treatment_Guidelines_2016w.pdf","article-title":null,"journal-title":null,"doi-asserted-by":null}],"short-title":[],"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9,1]]}},"content-domain":{"domain":[],"crossmark-restriction":false},"original-title":[],"container-title":["JAMA Dermatology"],"published-print":{"date-parts":[[2023,9,1]]},"reference-count":15,"published-online":null,"references-count":15,"short-container-title":["JAMA Dermatol"],"is-referenced-by-count":12},"unpaywall":{"doi":"10.1001/jamadermatol.2023.2167","is_oa":true,"title":"Self-Help Habit Replacement in Individuals With Body-Focused Repetitive Behaviors","updated":"2025-07-30T00:59:52+00:00","published_date":"2023-07-19","best_oa_location":{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10357355","pmh_id":"oai:pubmedcentral.nih.gov:10357355","url_for_pdf":null,"url_for_landing_page":"https://www.ncbi.nlm.nih.gov/pmc/articles/10357355"}}},"created_at":"2025-09-20T19:03:11.495Z","updated_at":"2025-09-20T22:56:47.429Z","tags":[{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"category","value":"Dermatology","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"condition","value":"Body-Focused Repetitive Behaviors","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"impact_flag","value":"limited_evidence","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"level_of_evidence","value":"2","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"modality","value":"Behavioral Therapy","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"sample_size","value":"n=268","value_numeric":268},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"sex","value":"mixed","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"study_design","value":"Randomized Controlled Trial","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"warning","value":"Diagnoses and outcomes were self-reported without external assessment.","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"warning","value":"No follow-up; durability of effect is unknown.","value_numeric":null},{"paper_doi":"10.1001/jamadermatol.2023.2167","tag_type":"warning","value":"Wait-list control rather than an active comparator.","value_numeric":null}],"summaries":{"what_studied":"An online randomized clinical trial in 2022 compared a 6-week self-help habit replacement program with a wait-list control in individuals with body-focused repetitive behaviors (n=268; 134 per arm), using the self-reported Generic BFRB Scale-45 as the primary outcome.","key_result":"Habit replacement outperformed wait-list on the GBS-45 in both per-protocol (ηp2=0.068; P=.001) and intention-to-treat analyses (ηp2=0.019; P=.02). On the Clinical Global Impressions scale, 52.8% in the habit replacement group reported improvement vs 19.6% with wait-list (P<.001); moderation suggested greater benefit for nail biting.","limitations":"Diagnoses were not externally verified and assessments were self-reported. No follow-up data were collected.","practice_takeaway":"A brief self-help habit replacement approach reduced BFRB severity over 6 weeks vs wait-list, with about half reporting global improvement; benefits appeared strongest for nail biting. Expect limited impact on concomitant symptoms, and note the absence of follow-up."}}],"initialOffset":5,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"modality","value":"Behavioral Therapy"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Modalities","href":"/hub/tag/modality"},{"name":"Behavioral Therapy"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"modality","hub_tag_value":"Behavioral Therapy"}}}]]

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