2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:Tad9,Treatment for cognitive dysfunction due to postacute sequelae of long COVID (ie, symptoms of fatigue, malaise, weakness, confusion that persist beyond 12 weeks after an initial COVID infection) remains a significant unmet need. To test evidence-based rehabilitation strategies for improving cognitive symptoms in persons with long COVID. This was a 5-arm, multicenter, randomized clinical trial of 3 remotely delivered interventions conducted between August 17, 2023, and June 10, 2024. The study took place at 22 trial sites and included the screening of individuals with cognitive long COVID. Participants were randomized to 1 of 5 arms: adaptive computerized cognitive training (BrainHQ [Posit Science]), cognitive-behavioral rehabilitation involving both group and individual counseling sessions (PASC-Cognitive Recovery [PASC-CoRE]) paired with BrainHQ, and transcranial direct current stimulation (tDCS) paired with BrainHQ. Two comparator arms were included as follows: unstructured computer puzzles and games (active comparator) and sham tDCS paired with BrainHQ. The interventions occurred 5 times per week over 10 weeks. Cognitive and behavioral in-person assessments were performed at baseline, midintervention, at the end of intervention, and 3 months after the end of the intervention. The primary outcome measure was the modified Everyday Cognition Scale 2 (ECog2) completed at the end of the intervention compared to the baseline visit based on participant self-report looking back over the prior 7 days. A total of 378 individuals were screened, from which there were 328 participants (median [IQR] age, 48.0 [37.0-58.0] years; 241 female [73.5%]; race: 15 Asian [4.6%], 47 Black [14.3%], and 235 White [71.6%]; ethnicity: 52 Hispanic [15.9%]). None of the 3 active interventions demonstrated benefits on the modified ECog2 in the intention-to-treat population by the end of the intervention period. The adjusted differences in mean change were 0.0 (95% CI, -0.2 to 0.2) for BrainHQ vs active comparator, 0.1 (95% CI, -0.1 to 0.3) for PASC-CoRE + BrainHQ vs active comparator, 0.0 (95% CI, -0.2 to 0.2) for tDCS-active + BrainHQ vs tDCS-sham + BrainHQ, and 0.1 (95% CI, -0.1 to 0.3) for PASC-CoRE + BrainHQ vs BrainHQ alone. Secondary participant-reported outcomes and neuropsychological tests showed no differential benefits for any treatment arm. All 5 arms demonstrated some improvements over time on the modified ECog2 and on secondary outcomes. There were no serious adverse events attributable to the interventions. This phase 2 randomized clinical trial failed to demonstrate differential benefits for online cognitive training, a structured cognitive rehabilitation program, and tDCS for cognitive long COVID. ClinicalTrials.gov Identifier: NCT05965739.31:T10c1, Importance Treatment for cognitive dysfunction due to postacute sequelae of long COVID (ie, symptoms of fatigue, malaise, weakness, confusion that persist beyond 12 weeks after an initial COVID infection) remains a significant unmet need. Objective To test evidence-based rehabilitation strategies for improving cognitive symptoms in persons with long COVID. Design, Setting, and Participants This was a 5-arm, multicenter, randomized clinical trial of 3 remotely delivered interventions conducted between August 17, 2023, and June 10, 2024. The study took place at 22 trial sites and included the screening of individuals with cognitive long COVID. Interventions Participants were randomized to 1 of 5 arms: adaptive computerized cognitive training (BrainHQ [Posit Science]), cognitive-behavioral rehabilitation involving both group and individual counseling sessions (PASC-Cognitive Recovery [PASC-CoRE]) paired with BrainHQ, and transcranial direct current stimulation (tDCS) paired with BrainHQ. Two comparator arms were included as follows: unstructured computer puzzles and games (active comparator) and sham tDCS paired with BrainHQ. The interventions occurred 5 times per week over 10 weeks. Main Outcomes and Measures Cognitive and behavioral in-person assessments were performed at baseline, midintervention, at the end of intervention, and 3 months after the end of the intervention. The primary outcome measure was the modified Everyday Cognition Scale 2 (ECog2) completed at the end of the intervention compared to the baseline visit based on participant self-report looking back over the prior 7 days. Results A total of 378 individuals were screened, from which there were 328 participants (median [IQR] age, 48.0 [37.0-58.0] years; 241 female [73.5%]; race: 15 Asian [4.6%], 47 Black [14.3%], and 235 White [71.6%]; ethnicity: 52 Hispanic [15.9%]). None of the 3 active interventions demonstrated benefits on the modified ECog2 in the intention-to-treat population by the end of the intervention period. The adjusted differences in mean change were 0.0 (95% CI, −0.2 to 0.2) for BrainHQ vs active comparator, 0.1 (95% CI, −0.1 to 0.3) for PASC-CoRE + BrainHQ vs active comparator, 0.0 (95% CI, −0.2 to 0.2) for tDCS-active + BrainHQ vs tDCS-sham + BrainHQ, and 0.1 (95% CI, −0.1 to 0.3) for PASC-CoRE + BrainHQ vs BrainHQ alone. Secondary participant-reported outcomes and neuropsychological tests showed no differential benefits for any treatment arm. All 5 arms demonstrated some improvements over time on the modified ECog2 and on secondary outcomes. There were no serious adverse events attributable to the interventions. Conclusions and Relevance This phase 2 randomized clinical trial failed to demonstrate differential benefits for online cognitive training, a structured cognitive rehabilitation program, and tDCS for cognitive long COVID. Trial Registration ClinicalTrials.gov Identifier: NCT05965739 . 25:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Cognitive Training: modality Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Cognitive Training (modality). Clinician-written summaries and actionable practice insights. Updated daily.\",\"url\":\"https://www.reachrx.ai/hub/tag/modality/Cognitive%20Training\",\"breadcrumb\":{\"@type\":\"BreadcrumbList\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https://www.reachrx.ai\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research Hub\",\"item\":\"https://www.reachrx.ai/hub\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Modalities\",\"item\":\"https://www.reachrx.ai/hub/tag/modality\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Cognitive Training\",\"item\":\"https://www.reachrx.ai/hub/tag/modality/Cognitive%20Training\"}]}}"}}]],["$","$L2f",null,{"title":"Cognitive Training: Research & Clinical Takeaways","description":"Review evidence by treatment modality: Cognitive Training — concise summaries and practical next steps.","papers":[{"doi":"10.1038/s41582-026-01260-5","pmid":"42680930","title":"Symptomatic treatment for Alzheimer disease: current evidence and future directions","journal_title":"Nature Reviews Neurology","journal_issn":"1759-4758","published_at":"2026-09-01T00:00:00.000Z","url":"https://doi.org/10.1038/s41582-026-01260-5","source_score":18,"is_retracted":false,"is_open_access":false,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-09-10T06:20:03.402Z","updated_at":"2026-09-10T06:20:03.402Z","tags":[{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"age_group","value":"older_adult","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"brand","value":"Nuplazid","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"brand","value":"Rexulti","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"category","value":"Clinical Neurology","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"condition","value":"Alzheimer Disease","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"condition","value":"Mild Cognitive Impairment","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"condition","value":"Neuropsychiatric Symptoms of Dementia","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"blarcamesine","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"brexpiprazole","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"citalopram","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"donepezil","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"escitalopram","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"galantamine","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"memantine","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"mirtazapine","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"pimavanserin","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"rivastigmine","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"generic","value":"xanomeline","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"impact_flag","value":"practice_changing","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"level_of_evidence","value":"5","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"modality","value":"Atypical Antipsychotic","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"modality","value":"Cholinesterase Inhibitor","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"modality","value":"Cognitive Training","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"modality","value":"Multimodal Lifestyle Intervention","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"modality","value":"Muscarinic Agonist","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"modality","value":"NMDA Receptor Antagonist","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"modality","value":"Physical Exercise","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"modality","value":"Serotonin 5-HT2A Inverse Agonist","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"sex","value":"mixed","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"study_design","value":"Narrative Review","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"warning","value":"Brexpiprazole FDA approval for dementia-related agitation is referenced as 2026; this is consistent with the paper's publication date but is a very recent regulatory event that clinicians should verify against current labelling.","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"warning","value":"Full text was behind a paywall; structured data are drawn from the abstract, key points, and reference list only — specific effect sizes and trial-level numbers could not be verified.","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"warning","value":"Study design is described as a 'Review Article' in the publisher metadata; classified here as a Narrative Review rather than Systematic Review, as no formal PRISMA or systematic search methodology is described.","value_numeric":null},{"paper_doi":"10.1038/s41582-026-01260-5","tag_type":"warning","value":"The 'impact_flag' of practice_changing reflects the integration of new FDA-approved agents and biomarker-guided prescribing recommendations, but the underlying evidence base for several emerging agents remains early-phase or post hoc.","value_numeric":null}],"summaries":{"what_studied":"This review synthesizes evidence for pharmacological and non-pharmacological symptomatic therapies in Alzheimer disease (AD), covering cognition, function, and neuropsychiatric symptoms, including established agents (cholinesterase inhibitors, memantine), emerging drugs (brexpiprazole, pimavanserin, muscarinic agonists), and non-drug approaches (cognitive training, physical exercise, cognitive stimulation therapy, multimodal lifestyle programmes).","key_result":"Cholinesterase inhibitors and memantine provide modest but significant cognitive and functional benefits, with biomarker-stratified data suggesting greater benefit in confirmed AD pathology. Non-pharmacological interventions show small-to-moderate effects, strongest for cognitive training and structured exercise in mild cognitive impairment. For neuropsychiatric symptoms, personalized psychosocial interventions meaningfully reduce agitation and depression; brexpiprazole and pimavanserin offer incremental gains over atypical antipsychotics but with more favourable safety profiles.","limitations":"- Full text was not accessible; summary is based on abstract, key points, and reference list only, limiting depth of critical appraisal.\n- As a narrative review, it does not perform a de novo meta-analysis and may be subject to selective citation.\n- Biomarker-stratified analyses referenced are largely post hoc or observational, limiting causal inference about precision prescribing.","practice_takeaway":"Continue cholinesterase inhibitors and memantine as first-line symptomatic therapy, prioritising patients with confirmed AD biomarkers. For agitation, try personalized psychosocial approaches first; if pharmacotherapy is needed, brexpiprazole is now FDA-approved as a non-antipsychotic option with a more favourable safety profile than older atypical antipsychotics."}},{"doi":"10.1162/jocn.a.2618","pmid":"42237636","title":"Extensive Experience Remodels Neural Task Circuitry to Escape the\n Frontal Bottleneck and Increase Automaticity of Categorization","journal_title":"Journal of Cognitive Neuroscience","journal_issn":"0898-929X","published_at":"2026-05-20T00:00:00.000Z","url":"https://doi.org/10.1162/jocn.a.2618","source_score":126,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-06-10T14:24:28.553Z","updated_at":"2026-06-10T14:24:28.553Z","tags":[{"paper_doi":"10.1162/jocn.a.2618","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"category","value":"Neurosciences","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"condition","value":"Category Learning","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"condition","value":"Cognitive Automaticity","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"impact_flag","value":"practice_changing","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"level_of_evidence","value":"3","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"modality","value":"Cognitive Training","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"study_design","value":"Longitudinal Experimental Study","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"warning","value":"Exact sample size (N) is not reported in the abstract; the sample_size tag was omitted accordingly.","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"warning","value":"Stimuli are novel morphed car images delivered via mobile app — ecological validity to clinical or professional skill learning is inferential.","value_numeric":null},{"paper_doi":"10.1162/jocn.a.2618","tag_type":"warning","value":"Study design is best described as a longitudinal within-subjects experiment rather than a standard RCT; level of evidence set to 3 with this caveat.","value_numeric":null}],"summaries":{"what_studied":"This fMRI and EEG study examined how extensive training (>30,000 trials over 5–10 weeks) reshapes the neural circuitry for object categorization in adults, comparing brain responses after initial learning (~4 hr) versus after prolonged practice (~16 additional hours).","key_result":"Extensive training shifted category-selective responses from prefrontal cortex (pFC) to ventral occipito-temporal cortex (vOTC), reduced vOTC–pFC functional connectivity, and increased vOTC–motor connectivity; critically, reduced vOTC–pFC connectivity correlated with better dual-task categorization performance, indicating greater automaticity.","limitations":"Participants categorized novel morphed car stimuli via a mobile app — a highly controlled, artificial category that may not generalize to natural real-world category learning. The study lacked a longitudinal active control group to rule out general practice effects. Sample size and exact N are not reported in the abstract.","practice_takeaway":"For skills requiring rapid, automatic categorization (e.g., radiology reads, surgical pattern recognition), this study suggests that truly extensive practice — far beyond a few hours — may be needed to shift processing away from attentional bottlenecks and achieve reliable automaticity."}},{"doi":"10.1001/jamaneurol.2025.4415","pmid":"41212544","title":"Evaluation of Interventions for Cognitive Symptoms in Long COVID","journal_title":"JAMA Neurology","journal_issn":"2168-6149","published_at":"2025-11-10T00:00:00.000Z","url":"https://doi.org/10.1001/jamaneurol.2025.4415","source_score":131,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2026-01-16","doi":"10.1001/jamaneurol.2025.4415","days":"7","issn":"2168-6149","rank":"6","field":"Clinical Medicine","score":"131","category":"Clinical Neurology","categories":["Clinical Neurology"],"_categories":["Clinical Neurology"]},"pubmed":{"doi":"10.1001/jamaneurol.2025.4415","title":"Evaluation of Interventions for Cognitive Symptoms in Long COVID: A Randomized Clinical Trial.","journal":"JAMA neurology","methods":"","results":"A total of 378 individuals were screened, from which there were 328 participants (median [IQR] age, 48.0 [37.0-58.0] years; 241 female [73.5%]; race: 15 Asian [4.6%], 47 Black [14.3%], and 235 White [71.6%]; ethnicity: 52 Hispanic [15.9%]). None of the 3 active interventions demonstrated benefits on the modified ECog2 in the intention-to-treat population by the end of the intervention period. The adjusted differences in mean change were 0.0 (95% CI, -0.2 to 0.2) for BrainHQ vs active comparator, 0.1 (95% CI, -0.1 to 0.3) for PASC-CoRE + BrainHQ vs active comparator, 0.0 (95% CI, -0.2 to 0.2) for tDCS-active + BrainHQ vs tDCS-sham + BrainHQ, and 0.1 (95% CI, -0.1 to 0.3) for PASC-CoRE + BrainHQ vs BrainHQ alone. Secondary participant-reported outcomes and neuropsychological tests showed no differential benefits for any treatment arm. All 5 arms demonstrated some improvements over time on the modified ECog2 and on secondary outcomes. There were no serious adverse events attributable to the interventions.","abstract":"$30","keywords":[],"pubmed_id":"41212544","conclusions":"","publication_date":"2025-11-10T00:00:00"},"crossref":{"DOI":"10.1001/jamaneurol.2025.4415","URL":"https://doi.org/10.1001/jamaneurol.2025.4415","ISSN":["2168-6149"],"link":[{"URL":"https://jamanetwork.com/journals/jamaneurology/articlepdf/2841155/jamaneurology_knopman_2025_oi_250076_1767644884.87942.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":"49","type":"journal-article","issue":"1","score":1,"title":["Evaluation of Interventions for Cognitive Symptoms in Long COVID"],"author":[{"given":"David S.","family":"Knopman","sequence":"first","affiliation":[{"name":"Department of Neurology, Mayo Clinic, Rochester, Minnesota"}]},{"given":"Deborah","family":"Koltai","sequence":"additional","affiliation":[{"name":"Department of Neurology, Duke University School of Medicine, Durham, North Carolina"}]},{"given":"Daniel T.","family":"Laskowitz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Duke University School of Medicine, Durham, North Carolina"}]},{"given":"Jacqueline","family":"Becker","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}]},{"given":"Leigh","family":"Charvet","sequence":"additional","affiliation":[{"name":"Department of Neurology, Grossman School of Medicine, New York University, New York"}]},{"given":"Juan","family":"Wisnivesky","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}]},{"given":"Alex","family":"Federman","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}]},{"given":"Adam","family":"Silverstein","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"}]},{"given":"Yuliya","family":"Lokhnygina","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"},{"name":"Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina"}]},{"given":"Giuseppina","family":"Pilloni","sequence":"additional","affiliation":[{"name":"Department of Neurology, Grossman School of Medicine, New York University, New York"}]},{"given":"Michelle","family":"Haddad","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, Georgia"}]},{"given":"Henry","family":"Mahncke","sequence":"additional","affiliation":[{"name":"Posit Science, San Francisco, California"}]},{"given":"Tom","family":"Van Vleet","sequence":"additional","affiliation":[{"name":"Posit Science, San Francisco, California"}]},{"given":"Rong","family":"Huang","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"}]},{"given":"Wendy","family":"Cox","sequence":"additional","affiliation":[{"name":"RECOVER Patient, Caregiver, or Community Representative, Durham, North Carolina"}]},{"given":"Diana","family":"Terry","sequence":"additional","affiliation":[{"name":"RECOVER Patient, Caregiver, or Community Representative, Durham, North Carolina"}]},{"given":"Jeannie","family":"Karwowski","sequence":"additional","affiliation":[{"name":"RECOVER Patient, Caregiver, or Community Representative, Durham, North Carolina"}]},{"given":"Netia","family":"McCray","sequence":"additional","affiliation":[{"name":"RECOVER Patient, Caregiver, or Community Representative, Durham, North Carolina"}]},{"given":"Jenny J.","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}]},{"given":"Grace A.","family":"McComsey","sequence":"additional","affiliation":[{"name":"Department of Medicine and Pediatrics, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio"}]},{"given":"Upinder","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Iowa, Iowa City"}]},{"given":"Linda N.","family":"Geng","sequence":"additional","affiliation":[{"name":"Department of Medicine, Stanford University School of Medicine, Stanford, California"}]},{"given":"Helen Y.","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Washington, Seattle"}]},{"given":"Rebecca","family":"Reece","sequence":"additional","affiliation":[{"name":"Department of Medicine, West Virginia University School of Medicine, Morgantown"}]},{"given":"James","family":"Moy","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois"}]},{"given":"Zoe","family":"Arvanitakis","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois"}]},{"given":"Sairam","family":"Parthasarathy","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Arizona, Tucson"}]},{"given":"Thomas F.","family":"Patterson","sequence":"additional","affiliation":[{"name":"Department of Medicine/Infectious Diseases, University of Texas Health San Antonio, San Antonio"}]},{"given":"Aditi","family":"Gupta","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Neurology, University of Kansas Medical Center, Kansas City"}]},{"given":"Luis","family":"Ostrosky-Zeichner","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, University of Texas Health Science Center at Houston, Houston"}]},{"given":"Jeffrey","family":"Parsonnet","sequence":"additional","affiliation":[{"name":"Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire"}]},{"given":"Elaine T.","family":"Kiriakopoulos","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dartmouth Health, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire"}]},{"given":"Tamara G.","family":"Fong","sequence":"additional","affiliation":[{"name":"Department of Neurology, Beth Israel Deaconess Medical Center and Harvard School of Medicine, Boston, Massachusetts"}]},{"given":"Janet","family":"Mullington","sequence":"additional","affiliation":[{"name":"Department of Neurology, Beth Israel Deaconess Medical Center and Harvard School of Medicine, Boston, Massachusetts"}]},{"given":"Sarah","family":"Jolley","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, University of Colorado Anschutz Medical Center, Aurora"}]},{"given":"Nirav S.","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Endeavor Health, Evanston, Illinois"}]},{"given":"Sarah Shizuko","family":"Morimoto","sequence":"additional","affiliation":[{"name":"Population Health Sciences, Division of Health Systems Innovation and Research, University of Utah School of Medicine, Salt Lake City"}]},{"given":"Joyce K.","family":"Lee-Iannotti","sequence":"additional","affiliation":[{"name":"Department of Neurology, Barrow Neurological Institute, University of Arizona College of Medicine—Phoenix, Phoenix"}]},{"given":"William D. S.","family":"Killgore","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Arizona, Tucson"}]},{"given":"Brigid","family":"Dwyer","sequence":"additional","affiliation":[{"name":"Chobanian & Avedisian School of Medicine at Boston University, Boston, Massachusetts"}]},{"given":"William","family":"Stringer","sequence":"additional","affiliation":[{"name":"Department of Medicine, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California"}]},{"given":"Carmen","family":"Isache","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Florida-Jacksonville, Jacksonville"}]},{"given":"Jennifer A.","family":"Frontera","sequence":"additional","affiliation":[{"name":"Department of Neurology, Grossman School of Medicine, New York University, New York"}]},{"given":"Jerry A.","family":"Krishnan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Illinois Research Network and University of Illinois Chicago, Chicago"}]},{"given":"Ashley","family":"O’Steen","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"}]},{"given":"Melissa","family":"James","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"}]},{"given":"Barrie L.","family":"Harper","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"}]},{"given":"Kanecia O.","family":"Zimmerman","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"},{"name":"Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina"}]},{"given":null,"family":null,"sequence":"additional","affiliation":[]},{"given":"Andrew","family":"Lawler","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Brandon","family":"Johnson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Chloe","family":"Pitsch","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Elen","family":"Feuerriegel","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jeff","family":"McKeehan","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Joie","family":"Molden","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kayleigh","family":"Reid","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kristine","family":"Erlandson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sarah","family":"Dowling","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Thomas","family":"Wodushek","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Diara","family":"Canton","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Dilara","family":"Turut","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ethan","family":"Sheppard","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jennifer","family":"Scott-Sutherland","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kristine","family":"Hauser","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Lynn","family":"Shaughnessy","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Michael","family":"Doyle","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Michelle","family":"Beck","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sabrina","family":"Heisey","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Vaishanvi","family":"Katragadda","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Amidat","family":"Yusuff","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Amy","family":"Perlack","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Anh","family":"Tran","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Brigid","family":"Dwyer","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Caroline","family":"Altaras","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Christie","family":"Merisme","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"David","family":"Krause","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Duncan","family":"Schulte","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Fabiola","family":"Dupre","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Gina","family":"Sanchez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Maxine","family":"Krengel","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Monica","family":"Ly","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Olanike","family":"Asupoto","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Quinneil","family":"Simmons","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ryan","family":"Schroeder","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Shannon","family":"Timlin","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ycar","family":"Devis","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Della","family":"Carter","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Leomaris","family":"Caceres","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Miguel","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Zariya","family":"Alvarez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Amin","family":"Yakubov","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Celia","family":"Engelson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Michael","family":"Reyes","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Alvin","family":"Youkhana","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Cheryl","family":"Jennings","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"David","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Dina","family":"Naquiallah","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Dylan","family":"Behun","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ellen","family":"Stephen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Emily","family":"Timm","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Farrah","family":"Bilimoria","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Grace","family":"Li","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jakob","family":"Stricker","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jimena","family":"Torres","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Maria","family":"Garcia","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Michelle","family":"Thomas","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Minnie","family":"Kang","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Rebeca","family":"Suarez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Tania","family":"Carmona","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ana","family":"Ramirez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Grace","family":"Kadubek","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Aileen","family":"Baker","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Andrea","family":"Romo-Serna","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Barbara","family":"Predki","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Cindy","family":"Leman","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Cristina","family":"Panhans","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Genevieve","family":"Roth","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Gowrisree","family":"Rudraraju","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Hannah","family":"Miller","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Julie","family":"DeLisa","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kat","family":"Williams","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kimberly","family":"Woodson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kyle","family":"Jennette","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Laura","family":"Carrera","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Laura","family":"Villanueva","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Maria","family":"Norwick","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Mariam","family":"Martinez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Matt","family":"Rowley","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Melissa","family":"Rutherford","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Michael","family":"Carrithers","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Neil","family":"Pliskin","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Nicolas","family":"Perez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Nicole","family":"Durkin","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Nikita","family":"Maniar","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Rachel","family":"Beety","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Raktima","family":"Daspgupta","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ramaswamy","family":"Ramchandran","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ruthie","family":"Jaramillo","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sharon","family":"Hasek","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Susy","family":"Macias","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Tina","family":"Schuh","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sarah","family":"Ialacci","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Christopher","family":"Bailey","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Danielle","family":"Labbato","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Amanda","family":"Hautmann","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Beth","family":"Smith","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Dia","family":"Nath","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jessica","family":"Meyer","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kathryn","family":"DiFrancesco","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kevin","family":"Walkup","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kimberly","family":"Pettinato","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Lynette","family":"Curtis","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Joviane","family":"Daher","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sarah","family":"Scott","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ziad","family":"Koberssy","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Caleb","family":"Mavar","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"John","family":"Andrefsky","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Alexander","family":"Merheb","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Carla","family":"Hernandez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jhony","family":"Baissary","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ornina","family":"Atieh","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Carol","family":"Pereira","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Deborah","family":"Carpenter","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jennifer","family":"Raynor","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kristine","family":"Brunton","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Andreea","family":"Podgoreanu","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Pyper","family":"Bunch","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Richard","family":"Brown","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sean","family":"O'Brien","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sheila","family":"Dickey","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Steven","family":"McNulty","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Varsha","family":"Gajjar","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Alec","family":"Neale","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Cari","family":"Cohen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Carolina","family":"Escobar","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Elizabeth","family":"Geary","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Franco","family":"Campanella","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kirsten","family":"Anderson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Laura","family":"Prestige","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Leslie","family":"Guidotti-Breting","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Megan","family":"Biewer","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Melissa","family":"Morton","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Nicholas","family":"Mathenia","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Oluwadamilola","family":"Adeyemi","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Samanike","family":"Hengst","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Wei Ning","family":"Chi","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Adam","family":"Vanderloo","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Amanda","family":"Caplan","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"July","family":"Chen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Mary Ellen","family":"Acree","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Michael","family":"Glickman","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Mukund","family":"Nakhate","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Zaw Nu","family":"Dan","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Phyliis","family":"Switzer","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Shambhu","family":"Aryal","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jessica","family":"Sanchez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Luke","family":"Sims","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Rebecca","family":"Ferdinand","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Mehriban","family":"Mammadova","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Carolyn","family":"Grimes","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Elizabeth","family":"Vidales","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Hoai Phuang","family":"Pham","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"John","family":"Lopez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Laura","family":"Nielsen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Maryjane","family":"Keller","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Syeda","family":"Uruba","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Maria","family":"Hernandez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Bela","family":"Patel","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Matthew","family":"Lin","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Virginia","family":"Umana-Sanchez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Chong","family":"Pak","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jeffery","family":"Gainer","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Renae","family":"Burr","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ashleigh","family":"Trapuzzano","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Brian","family":"Celso","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Grace","family":"Bienkowski","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jennifer","family":"Bowman","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jorge","family":"Verdecia","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kathryn","family":"Zerwekh","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Liliana","family":"Serrano","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Meghan","family":"Marotz","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Piper","family":"Propp","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Yonatan","family":"Sarig","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Annie","family":"Murphy","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Brandon","family":"Comfort","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Gina","family":"Brown","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Iri","family":"Torres","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jeffrey","family":"Klein","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jessica","family":"Reed","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"John","family":"Walker","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"John","family":"Moore","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Lisa","family":"Tempest-Browning","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Mudassar","family":"Arain","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Pamela","family":"Kemp","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Samantha","family":"Sullivan","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sean","family":"Obrien","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sonja","family":"Way","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jessica","family":"Chevalier","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Carly","family":"Sykes","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Carrie","family":"Kruck","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Elaine","family":"Kiriakopoulos","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Lisa","family":"Sackett","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sarah","family":"Kaden","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Claire","family":"Bang","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Mary","family":"Hynes","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Torrey","family":"Gallagher","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Margaret","family":"Childers-Kakos","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ahmad","family":"Zia","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Amy","family":"South","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Anne","family":"Oravets","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Carolyn","family":"Ferreyra","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Chad","family":"Glaze","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Daphne-Dominique","family":"Villanueva","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Erica","family":"Blystone","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jane","family":"Pritchard","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Laura","family":"Alyward","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Melissa","family":"Cooper","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Michelle","family":"Chidester","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Rachael","family":"Alderson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Renee","family":"Clark","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sally","family":"Hodder","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Arif","family":"Sarwari","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"James","family":"Bardes","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Joy","family":"Juskowich","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Shelly","family":"Welch","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Alyssa","family":"Civil","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ashley","family":"Bendl","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Elisa","family":"Dicker","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Hannah","family":"Hanson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Heather","family":"Viola","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Janice","family":"Morinigo","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Karisma","family":"Pantaleon","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kathryn","family":"Marcon","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kimberly","family":"Stone","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kiwan","family":"Stewart","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Lorraine","family":"Evo-Ortega","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Maria","family":"Loizos","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Megan","family":"McVeety","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sabina","family":"Guliyeva","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Eric","family":"Watson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Shayna","family":"Pehel","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Tim","family":"Ko","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Leah","family":"Caropolo","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Huriye Deniz","family":"Kocas","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Luis","family":"Fernandez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Andrew","family":"ODonnell","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Corey","family":"Saperia","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Daniel","family":"Thai","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Divya","family":"Pathak","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jennifer","family":"Keller","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kelly","family":"Olszewski","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kimberly","family":"Clinton","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kirsten","family":"Cherian","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Layton","family":"Dutton","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ma","family":"Elepano","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Rebecca","family":"Lin","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sukanya","family":"Mohapatra","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ting","family":"Chen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Tonita","family":"Wroolie","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Zenita","family":"Leang","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sumana","family":"Shashidhar","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Tiffany","family":"Nguyen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ashwath","family":"Ravisankar","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Brycie","family":"Weiden","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Daniel","family":"Brown","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Dawn","family":"Bolliger","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Heather","family":"Glesne","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jennifer","family":"Dixon","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Praneeth","family":"Chebrolu","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Zarine","family":"Gazali","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Whitney","family":"Hurst","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Avery","family":"Fry","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ganesh","family":"Murthy","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Garrett","family":"Grischo","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Heidi","family":"Erickson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Isaias","family":"Gomez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jacquelynn","family":"Copeland","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Judy","family":"Galaz","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Lynn","family":"Autry","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Marjorie","family":"Dilise-Russo","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Michelle","family":"James","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Mrinalini","family":"Kala","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Nikki","family":"Marshell","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sabine","family":"Borwege","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sheila","family":"Vadovicky","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Stephanie","family":"Marsh","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"William","family":"Hartley","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Linda","family":"Murtagh","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Anna","family":"Kennedy","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Annie","family":"Meltzer-Christensen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Caitlyn","family":"Stringham","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ella","family":"Gaskin","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Melissa","family":"Judd","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ryan","family":"Smith","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sarah","family":"Cote","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Shreya","family":"Mahasenan","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Todd","family":"Bjorklund","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Cheryl","family":"Farner","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Barbara","family":"Taylor","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Bridgette","family":"Soileau","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Cyrena","family":"Cote","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Gabrielle","family":"Hromas","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Irma","family":"Scholler","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Lisa","family":"Longoria","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Patricia","family":"Heard","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Hillary","family":"Johnson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Johnnie","family":"Jones","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Robin","family":"Tragus","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Maya","family":"Harris","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Alexis","family":"Pinones","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Alyssa","family":"Anderson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Gabrielyd","family":"Hastings","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"jessica","family":"Courtright","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jessica","family":"Hernandez","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Madhumita","family":"Jayakumar","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Melinda","family":"Fischer","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Michael","family":"Sullivan","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Pamela","family":"Solis","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Alex","family":"Harteloo","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Anna","family":"Elias-Warren","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Daniel","family":"Nguyen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Dylan","family":"McDonald","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Helen","family":"Nguyen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Holly","family":"Rau","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jean","family":"Mernaugh","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jennifer","family":"Logue","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kathleen","family":"Pagulayan","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kino","family":"Watanabe","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kristen","family":"Huden","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Laurel","family":"Peabody","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Tiffany","family":"Mei","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Catherine","family":"Ogunwuyi","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Esther","family":"Cobbina","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ian","family":"Sankar","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Lisa","family":"Nguyen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Nicole","family":"Fromm","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Rowan","family":"Arnold","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Stephanie","family":"Ogu","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ying","family":"Yuan","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Homam","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Izabella","family":"Szum","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jignesh","family":"Patel","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sonia","family":"Sultan","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Yasmin","family":"Jazayeri","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Timothy","family":"Hatlen","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Betty","family":"Anderson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Isabel","family":"Munoz","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Logan","family":"Rhys","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Matthew","family":"Wright","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ryan","family":"Vane","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Jessica","family":"Kim","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Leticia","family":"Diaz","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Nathan","family":"Yee","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Robert","family":"Gruhn","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Sarah","family":"Browngoetz","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Thomas","family":"Decato","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Elisha","family":"Johnson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Arista","family":"Chand","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ernesto","family":"Ortiz","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Ken","family":"Bottrill","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Kymberly","family":"Henderson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Lindsey","family":"Hildebrand","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Marketta","family":"Johnson","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Richard","family":"DeArmond","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]},{"given":"Trina","family":"Hughes","sequence":"additional","affiliation":[{"name":"for the RECOVER-NEURO Clinical Trial Group"}]}],"issued":{"date-parts":[[2026,1,1]]},"member":"10","prefix":"10.1001","source":"Crossref","volume":"83","created":{"date-time":"2025-11-10T16:30:56Z","timestamp":1762792256000,"date-parts":[[2025,11,10]]},"indexed":{"date-time":"2026-01-12T19:27:25Z","timestamp":1768246045111,"date-parts":[[2026,1,12]]},"subject":[],"abstract":"$31","language":"en","relation":{},"resource":{"primary":{"URL":"https://jamanetwork.com/journals/jamaneurology/fullarticle/2841155"}},"subtitle":["A Randomized Clinical Trial"],"deposited":{"date-time":"2026-01-12T16:01:11Z","timestamp":1768233671000,"date-parts":[[2026,1,12]]},"issn-type":[{"type":"print","value":"2168-6149"}],"published":{"date-parts":[[2026,1,1]]},"publisher":"American Medical Association (AMA)","reference":[{"DOI":"10.1001/jama.2024.11370","key":"noi250076r1","year":"2024","issue":"1","author":"Fang","volume":"332","first-page":"5","unstructured":null,"article-title":"Evidence mounts that about 7% of us adults have had Long COVID.","journal-title":"JAMA","doi-asserted-by":"crossref"},{"DOI":"10.1038/s41591-022-02001-z","key":"noi250076r2","year":"2022","issue":"11","author":"Xu","volume":"28","first-page":"2406","unstructured":null,"article-title":"Long-term neurologic outcomes of COVID-19.","journal-title":"Nat Med","doi-asserted-by":"crossref"},{"DOI":null,"key":"noi250076r3","year":"2024","issue":null,"author":"Buer","volume":"41","first-page":null,"unstructured":null,"article-title":"Executive deficits after SARS-CoV-2 infection: a cross-sectional population study.","journal-title":"Brain Behav Immun Health","doi-asserted-by":null},{"DOI":"10.1056/NEJMoa2311330","key":"noi250076r4","year":"2024","issue":"9","author":"Hampshire","volume":"390","first-page":"806","unstructured":null,"article-title":"Cognition and memory after COVID-19 in a large community sample.","journal-title":"N Engl J Med","doi-asserted-by":"crossref"},{"DOI":"10.1111/jgs.14132","key":"noi250076r5","year":"2016","issue":"6","author":"Lin","volume":"64","first-page":"1293","unstructured":null,"article-title":"Cognitive and neural effects of vision-based speed-of-processing training in older adults with amnestic mild cognitive impairment: A pilot study.","journal-title":"J Am Geriatr Soc","doi-asserted-by":"crossref"},{"DOI":"10.1371/journal.pone.0177177","key":"noi250076r6","year":"2017","issue":"5","author":"Charvet","volume":"12","first-page":null,"unstructured":null,"article-title":"Cognitive function in multiple sclerosis improves with telerehabilitation: results from a randomized controlled trial.","journal-title":"PLoS One","doi-asserted-by":"crossref"},{"DOI":"10.1080/13607863.2018.1534080","key":"noi250076r7","year":"2020","issue":"3","author":"Turner","volume":"24","first-page":"464","unstructured":null,"article-title":"Goal-Oriented Attention Self-Regulation (GOALS) training in older adults.","journal-title":"Aging Ment Health","doi-asserted-by":"crossref"},{"DOI":"10.1177/1352458517732842","key":"noi250076r8","year":"2018","issue":"13","author":"Charvet","volume":"24","first-page":"1760","unstructured":null,"article-title":"Remotely supervised transcranial direct current stimulation for the treatment of fatigue in multiple sclerosis: Results from a randomized, sham-controlled trial.","journal-title":"Mult Scler","doi-asserted-by":"crossref"},{"DOI":"10.1186/s13063-024-08156-z","key":"noi250076r9","year":"2024","issue":"1","author":"Knopman","volume":"25","first-page":"326","unstructured":null,"article-title":"RECOVER-NEURO: study protocol for a multicenter, multiarm, phase 2, randomized, active comparator trial evaluating 3 interventions for cognitive dysfunction in postacute sequelae of SARS-CoV-2 infection (PASC).","journal-title":"Trials","doi-asserted-by":"crossref"},{"DOI":"10.1016/j.brs.2015.01.401","key":"noi250076r11","year":"2015","issue":"3","author":"Seibt","volume":"8","first-page":"590","unstructured":null,"article-title":"The pursuit of DLPFC: nonneuronavigated methods to target the left dorsolateral prefrontal cortex with symmetric bicephalic transcranial direct current stimulation (tDCS).","journal-title":"Brain Stimul","doi-asserted-by":"crossref"},{"DOI":"10.1002/hbm.24420","key":"noi250076r12","year":"2019","issue":"3","author":"Li","volume":"40","first-page":"904","unstructured":null,"article-title":"Brain state and polarity dependent modulation of brain networks by transcranial direct current stimulation.","journal-title":"Hum Brain Mapp","doi-asserted-by":"crossref"},{"DOI":"10.1016/j.cortex.2018.11.022","key":"noi250076r13","year":"2019","issue":null,"author":"Hill","volume":"113","first-page":"37","unstructured":null,"article-title":"Impact of concurrent task performance on transcranial direct current stimulation (tDCS)–induced changes in cortical physiology and working memory.","journal-title":"Cortex","doi-asserted-by":"crossref"},{"DOI":"10.1038/s41467-023-38910-x","key":"noi250076r14","year":"2023","issue":"1","author":"Antonenko","volume":"14","first-page":"3184","unstructured":null,"article-title":"Microstructural and functional plasticity following repeated brain stimulation during cognitive training in older adults.","journal-title":"Nat Commun","doi-asserted-by":"crossref"},{"DOI":"10.1007/s11357-024-01077-4","key":"noi250076r15","year":"2024","issue":"3","author":"Kraft","volume":"46","first-page":"3325","unstructured":null,"article-title":"The impact of a tDCS and cognitive training intervention on task-based functional connectivity.","journal-title":"Geroscience","doi-asserted-by":"crossref"},{"DOI":"10.1097/WAD.0000000000000450","key":"noi250076r16","year":"2021","issue":"3","author":"Farias","volume":"35","first-page":"258","unstructured":null,"article-title":"The Measurement of Everyday Cognition (ECog): revisions and updates.","journal-title":"Alzheimer Dis Assoc Disord","doi-asserted-by":"crossref"},{"DOI":"10.1097/01.mlr.0000258615.42478.55","key":"noi250076r17","year":"2007","issue":"5","author":"Cella","volume":"45","first-page":"S3","unstructured":null,"article-title":"The Patient-Reported Outcomes Measurement Information System (PROMIS): progress of an NIH Roadmap cooperative group during its first 2 years.","journal-title":"Med Care","doi-asserted-by":"crossref"},{"DOI":"10.1093/arclin/10.2.133","key":"noi250076r18","year":"1995","issue":"2","author":"Uchiyama","volume":"10","first-page":"133","unstructured":null,"article-title":"Alternate forms of the Auditory-Verbal Learning Test: issues of test comparability, longitudinal reliability, and moderating demographic variables.","journal-title":"Arch Clin Neuropsychol","doi-asserted-by":"crossref"},{"DOI":"10.1093/arclin/9.4.303","key":"noi250076r19","year":"1994","issue":"4","author":"Geffen","volume":"9","first-page":"303","unstructured":null,"article-title":"Test-retest reliability of a new form of the auditory verbal learning test (AVLT).","journal-title":"Arch Clin Neuropsychol","doi-asserted-by":"crossref"},{"DOI":null,"key":"noi250076r22","year":"2013","issue":"11","author":"Weintraub","volume":"80","first-page":"S54","unstructured":null,"article-title":"Cognition assessment using the NIH Toolbox.","journal-title":"Neurology","doi-asserted-by":null},{"DOI":"10.3390/diagnostics8030066","key":"noi250076r23","year":"2018","issue":"3","author":"Cotler","volume":"8","first-page":"66","unstructured":null,"article-title":"A brief questionnaire to assess post-exertional malaise.","journal-title":"Diagnostics (Basel)","doi-asserted-by":"crossref"},{"DOI":"10.3390/jcm10214897","key":"noi250076r24","year":"2021","issue":"21","author":"Goudman","volume":"10","first-page":"4897","unstructured":null,"article-title":"The influence of missing data on disabilities in patients treated with high-dose spinal cord stimulation: a tipping point sensitivity analysis.","journal-title":"J Clin Med","doi-asserted-by":"crossref"},{"DOI":"10.1136/bmj-2024-081318","key":"noi250076r25","year":"2024","issue":null,"author":"Zeraatkar","volume":"387","first-page":null,"unstructured":null,"article-title":"Interventions for the management of long COVID (post-COVID condition): living systematic review.","journal-title":"BMJ","doi-asserted-by":"crossref"},{"DOI":"10.1093/brain/awad377","key":"noi250076r26","year":"2024","issue":"3","author":"McIntyre","volume":"147","first-page":"849","unstructured":null,"article-title":"Vortioxetine for the treatment of post-COVID-19 condition: a randomized controlled trial.","journal-title":"Brain","doi-asserted-by":"crossref"},{"DOI":"10.1001/jamanetworkopen.2024.36874","key":"noi250076r27","year":"2024","issue":"10","author":"Guttuso","volume":"7","first-page":null,"unstructured":null,"article-title":"Lithium aspartate for long COVID fatigue and cognitive dysfunction: a randomized clinical trial.","journal-title":"JAMA Netw Open","doi-asserted-by":"crossref"},{"DOI":"10.1001/jamainternmed.2024.2007","key":"noi250076r28","year":"2024","issue":"9","author":"Geng","volume":"184","first-page":"1024","unstructured":null,"article-title":"Nirmatrelvir-ritonavir and symptoms in adults with postacute sequelae of SARS-CoV-2 infection: the STOP-PASC randomized clinical trial.","journal-title":"JAMA Intern Med","doi-asserted-by":"crossref"},{"DOI":"10.1001/jamanetworkopen.2024.50744","key":"noi250076r29","year":"2024","issue":"12","author":"Nerli","volume":"7","first-page":null,"unstructured":null,"article-title":"Brief outpatient rehabilitation program for post-COVID-19 condition: a randomized clinical trial.","journal-title":"JAMA Netw Open","doi-asserted-by":"crossref"},{"DOI":"10.1038/s41386-024-01995-z","key":"noi250076r30","year":"2024","issue":"2","author":"Victoria","volume":"50","first-page":"472","unstructured":null,"article-title":"A digital intervention for cognitive deficits following COVID-19: a randomized clinical trial.","journal-title":"Neuropsychopharmacology","doi-asserted-by":"crossref"},{"DOI":"10.1016/j.brs.2023.01.1672","key":"noi250076r31","year":"2023","issue":"1","author":"Santana","volume":"16","first-page":"100","unstructured":null,"article-title":"Noninvasive brain stimulation for fatigue in postacute sequelae of SARS-CoV-2 (PASC).","journal-title":"Brain Stimul","doi-asserted-by":"crossref"},{"DOI":"10.1038/s41598-024-52763-4","key":"noi250076r32","year":"2024","issue":"1","author":"Klírová","volume":"14","first-page":"2193","unstructured":null,"article-title":"Transcranial direct current stimulation (tDCS) in the treatment of neuropsychiatric symptoms of long COVID.","journal-title":"Sci Rep","doi-asserted-by":"crossref"},{"DOI":"10.1016/j.brs.2025.03.011","key":"noi250076r33","year":"2025","issue":"3","author":"Mischke","volume":"18","first-page":"733","unstructured":null,"article-title":"Evaluating the efficacy of repetitive anodal transcranial direct current stimulation on cognitive fatigue in long COVID: a randomized controlled trial.","journal-title":"Brain Stimul","doi-asserted-by":"crossref"},{"DOI":null,"key":"noi250076r20","year":"1982","issue":null,"author":"Smith","volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":null},{"DOI":null,"key":"noi250076r21","year":"1995","issue":null,"author":"Lewis","volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":null},{"DOI":null,"key":"noi250076r10","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":"RECOVER. RECOVER clinical trials. Accessed October 16, 2025. https://trials.recovercovid.org/","article-title":null,"journal-title":null,"doi-asserted-by":null}],"short-title":[],"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,1]]}},"content-domain":{"domain":[],"crossmark-restriction":false},"original-title":[],"container-title":["JAMA Neurology"],"published-print":{"date-parts":[[2026,1,1]]},"reference-count":33,"published-online":null,"references-count":33,"short-container-title":["JAMA Neurol"],"is-referenced-by-count":2},"unpaywall":{"doi":"10.1001/jamaneurol.2025.4415","is_oa":true,"title":"Evaluation of Interventions for Cognitive Symptoms in Long COVID","updated":"2025-11-13T08:10:39+00:00","published_date":"2025-11-10","best_oa_location":{"url":"https://jamanetwork.com/journals/jamaneurology/articlepdf/2841155/jamaneurology_knopman_2025_oi_250076_1762182925.72946.pdf","pmh_id":null,"url_for_pdf":"https://jamanetwork.com/journals/jamaneurology/articlepdf/2841155/jamaneurology_knopman_2025_oi_250076_1762182925.72946.pdf","url_for_landing_page":"https://doi.org/10.1001/jamaneurol.2025.4415"}}},"created_at":"2026-01-19T09:31:36.873Z","updated_at":"2026-01-21T12:05:26.220Z","tags":[{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"brand","value":"BrainHQ","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"category","value":"Clinical Neurology","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"condition","value":"Long COVID","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"level_of_evidence","value":"2","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"modality","value":"Cognitive Rehabilitation","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"modality","value":"Cognitive Training","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"modality","value":"Transcranial Direct Current Stimulation","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"sample_size","value":"n=328","value_numeric":328},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"sex","value":"mixed","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"study_design","value":"Randomized Controlled Trial","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"warning","value":"Blinding is described for tDCS (active vs sham) but is unclear for other arms from the abstract.","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"warning","value":"Durability beyond 3 months post-intervention is not detailed in the abstract.","value_numeric":null},{"paper_doi":"10.1001/jamaneurol.2025.4415","tag_type":"warning","value":"Only abstract-level details are provided here; adherence, attrition, and arm-level ECog2 change scores are not reported.","value_numeric":null}],"summaries":{"what_studied":"A 5-arm, multicenter randomized clinical trial tested three remote interventions for cognitive long COVID—adaptive computerized cognitive training (BrainHQ), a structured cognitive-behavioral rehabilitation program (PASC-CoRE) plus BrainHQ, and active transcranial direct current stimulation (tDCS) plus BrainHQ—against unstructured computer games and sham tDCS plus BrainHQ. Adults with cognitive long COVID (n=328) trained 5 days per week for 10 weeks; the primary outcome was change in self-reported modified Everyday Cognition Scale 2 (ECog2) at end of intervention versus baseline.","key_result":"No intervention outperformed its comparator on the primary outcome: adjusted mean change differences on ECog2 were 0.0 (95% CI, -0.2 to 0.2) for BrainHQ vs active comparator, 0.1 (-0.1 to 0.3) for PASC-CoRE + BrainHQ vs active comparator, 0.0 (-0.2 to 0.2) for active vs sham tDCS (both with BrainHQ), and 0.1 (-0.1 to 0.3) for PASC-CoRE + BrainHQ vs BrainHQ alone. Secondary patient-reported and neuropsychological outcomes also showed no differential benefit; all arms improved over time, and no serious adverse events occurred.","practice_takeaway":"For adults with cognitive long COVID, 10 weeks of online cognitive training, structured cognitive rehabilitation, or tDCS did not improve self-reported everyday cognition beyond active control or sham. Expect some improvement over time regardless of assignment; the tested approaches appeared safe without serious adverse events."}}],"initialOffset":3,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"modality","value":"Cognitive Training"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Modalities","href":"/hub/tag/modality"},{"name":"Cognitive Training"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"modality","hub_tag_value":"Cognitive Training"}}}]]

Papers