2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:T744,Physical inactivity constitutes a pressing societal problem. To realize physical activity's (PA) potential as a key health resource, mechanisms of PA engagement need to be understood. Laboratory and interventional studies documented that exercise relates to affective well-being (AWB) and suggested that AWB may shape PA behaviour. Digitalization enabled the investigation of how PA relates to AWB in everyday life, but findings from individual studies are ambiguous. Here we compiled 67 datasets (55.2% of eligible records) including 321,345 smartphone-based AWB ratings and nearly 1,000,000 h of accelerometer-measured PA (N = 8,223 participants) until December 2023 to clarify the nature and extent of PA-AWB associations. One- and two-stage individual participant data meta-analyses reveal that momentary AWB is associated with both prior (within, r = 0.05, 99.2% confidence intervals (CI) 0.03 to 0.06; between, r = 0.08, 99.2% CI 0.04 to 0.12) and subsequent (within, r = 0.04, 99.2% CI 0.03 to 0.05; between, r = 0.08, 99.2% CI 0.04 to 0.13) short-term PA in everyday life. Within persons, PA displays a positive association with energetic arousal, positive affective states and valence, yet a negative relation to calmness. The practical effect sizes are comparable to other daily life activities, with energetic arousal evincing the strongest relation to PA. Considerable heterogeneity in associations across individuals can be partially explained by sociodemographic moderators. Between participants, PA relates to positive affective states. The results document the critical relevance of PA-AWB relations in everyday life. They can contribute to the revision and development of health behaviour models and establish a starting point to approach behavioural, physiological and neuronal mechanisms underlying PA-AWB associations.31:T90e,Abstract Physical inactivity constitutes a pressing societal problem. To realize physical activity’s (PA) potential as a key health resource, mechanisms of PA engagement need to be understood. Laboratory and interventional studies documented that exercise relates to affective well-being (AWB) and suggested that AWB may shape PA behaviour. Digitalization enabled the investigation of how PA relates to AWB in everyday life, but findings from individual studies are ambiguous. Here we compiled 67 datasets (55.2% of eligible records) including 321,345 smartphone-based AWB ratings and nearly 1,000,000 h of accelerometer-measured PA ( N = 8,223 participants) until December 2023 to clarify the nature and extent of PA–AWB associations. One- and two-stage individual participant data meta-analyses reveal that momentary AWB is associated with both prior (within, r = 0.05, 99.2% confidence intervals (CI) 0.03 to 0.06; between, r = 0.08, 99.2% CI 0.04 to 0.12) and subsequent (within, r = 0.04, 99.2% CI 0.03 to 0.05; between, r = 0.08, 99.2% CI 0.04 to 0.13) short-term PA in everyday life. Within persons, PA displays a positive association with energetic arousal, positive affective states and valence, yet a negative relation to calmness. The practical effect sizes are comparable to other daily life activities, with energetic arousal evincing the strongest relation to PA. Considerable heterogeneity in associations across individuals can be partially explained by sociodemographic moderators. Between participants, PA relates to positive affective states. The results document the critical relevance of PA–AWB relations in everyday life. They can contribute to the revision and development of health behaviour models and establish a starting point to approach behavioural, physiological and neuronal mechanisms underlying PA–AWB associations. 25:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Physical Activity / Exercise: modality Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Physical Activity / Exercise (modality). Clinician-written summaries and actionable practice insights. 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Conclusions are based on narrative synthesis of existing literature.","value_numeric":null}],"summaries":{"what_studied":"This AHA scientific statement evaluates the role of physical activity and exercise in promoting weight loss, weight loss maintenance, and cardiometabolic health in adults with overweight or obesity, across lifestyle, pharmacological, and surgical weight loss strategies.","key_result":"As a single treatment, physical activity is unlikely to achieve clinically meaningful weight loss (≥5% of initial body weight) unless aerobic activity levels are exceptionally high; however, combined with diet, medication, or surgery, it augments total weight loss and improves cardiometabolic outcomes — including hypertension, insulin resistance, and dyslipidemia — independent of weight loss.","limitations":"This is a narrative scientific statement, not a systematic review or meta-analysis, so conclusions reflect expert synthesis rather than pooled quantitative data. Specific effect sizes and absolute outcome numbers are not consistently reported across the reviewed evidence.","practice_takeaway":"Don't rely on exercise alone for clinically meaningful weight loss — pair physical activity with dietary changes, obesity medications, or surgery for best results. 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Moderator analyses, subgroup breakdowns, and secondary outcomes could not be independently verified from the full text.","value_numeric":null},{"paper_doi":"10.1038/s41562-026-02427-2","tag_type":"warning","value":"The study covers data up to December 2023; the publication date of May 2026 suggests a substantial lag that may affect currency of included datasets.","value_numeric":null}],"summaries":{"what_studied":"This individual participant data (IPD) meta-analysis examined how accelerometer-measured physical activity (PA) relates to smartphone-based affective well-being (AWB) in daily life, pooling 67 datasets (N = 8,223 participants, ~321,345 AWB ratings, ~1,000,000 h of PA data) collected up to December 2023.","key_result":"PA showed small but consistent positive associations with momentary AWB both before (within-person r = 0.05, between-person r = 0.08) and after (within-person r = 0.04, between-person r = 0.08) PA episodes. 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The negative link to calmness suggests PA may transiently increase arousal, which is worth discussing with patients who exercise for relaxation."}},{"doi":"10.1161/cir.0000000000001431","pmid":"42021760","title":"Physical Activity in Pediatric Cardiomyopathies: Moving for Health: A Scientific Statement From the American Heart Association","journal_title":"Circulation","journal_issn":"0009-7322","published_at":"2026-04-23T00:00:00.000Z","url":"https://doi.org/10.1161/cir.0000000000001431","source_score":52,"is_retracted":false,"is_open_access":false,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-05-07T22:51:05.992Z","updated_at":"2026-05-07T22:51:05.992Z","tags":[{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"age_group","value":"adolescent","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"age_group","value":"pediatric","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"category","value":"Cardiac & Cardiovascular Systems","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"condition","value":"Arrhythmogenic Cardiomyopathy","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"condition","value":"Dilated Cardiomyopathy","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"condition","value":"Hypertrophic Cardiomyopathy","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"condition","value":"Restrictive Cardiomyopathy","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"impact_flag","value":"practice_changing","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"level_of_evidence","value":"7","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"modality","value":"Implantable Cardioverter Defibrillator","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"modality","value":"Physical Activity / Exercise","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"sex","value":"mixed","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"study_design","value":"Scientific Statement / Expert Consensus","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"warning","value":"No original patient-level data are reported; this is an expert consensus/scientific statement — level of evidence reflects opinion and narrative review rather than a primary study.","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"warning","value":"Sample size tag is omitted as this is not a patient cohort study.","value_numeric":null},{"paper_doi":"10.1161/cir.0000000000001431","tag_type":"warning","value":"The claim that SCD risk is not higher in exercising cardiomyopathy patients is described as 'emerging' — the underlying studies are not detailed in the abstract, so the strength of that evidence cannot be independently verified from this source alone.","value_numeric":null}],"summaries":{"what_studied":"This AHA scientific statement evaluates the safety and benefits of physical activity (PA) in pediatric patients with hypertrophic, dilated, restrictive, or arrhythmogenic cardiomyopathy, including those with implantable cardioverter defibrillators (ICDs), and provides an updated framework for PA guidance using risk stratification, advanced imaging, exercise testing, and genotype-specific data.","key_result":"Emerging evidence challenges the longstanding restrictive PA paradigm: the risk of sudden cardiac death may not be higher in some cardiomyopathy patients who exercise vs. those who are sedentary, and PA may promote reverse cardiac remodeling. The statement concludes that most children and adolescents with cardiomyopathy can safely engage in PA with individualized assessment and shared decision-making.","limitations":"This is a consensus scientific statement, not a primary study — it does not report original trial data or specific event rates. The evidence base cited is described as 'emerging,' suggesting limited high-quality prospective studies in pediatric cardiomyopathy populations specifically.","practice_takeaway":"Clinicians should move away from blanket PA restriction in pediatric cardiomyopathy and instead use individualized risk stratification — including advanced imaging, exercise testing, and genotype — paired with shared decision-making to guide safe PA participation. Longitudinal surveillance is essential as clinical phenotypes evolve over time."}}],"initialOffset":3,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"modality","value":"Physical Activity / Exercise"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Modalities","href":"/hub/tag/modality"},{"name":"Physical Activity / Exercise"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"modality","hub_tag_value":"Physical Activity / Exercise"}}}]]

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