2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:T727,Management of complex hard-to-heal (chronic) wounds presents a substantial challenge in various healthcare settings where logistical constraints and patient-related factors can impede wound closure. This retrospective study evaluates outcomes associated with the use of a dehydrated, full-thickness placental allograft (CompleteFT; ExtremityCare, LLC, US) composed of the amnion, chorion and intermediate layers, when applied to complex hard-to-heal wounds in a mobile care environment. A retrospective analysis reviewed data collected between February 2024 and July 2025 from patients (aged ≥18 years) with complex hard-to-heal wounds. Data were retrieved from a single mobile wound care service provider team (Compassionate Care Concierge, US). Prior to allograft application, all wounds exhibited stalled healing for at least 30 days with standard of care (SoC). The allograft was applied to all wounds as an adjunct to SoC. Trend changes in wound surface area and percentage area reduction (PAR) across various wound aetiologies were assessed, with additional endpoints including the number of allograft applications and relevant patient parameters. The patient cohort (n=114, with a total of 184 hard-to-heal wounds), included 51 males and 63 females, with a mean age of 73.1 years. Analysis revealed statistically significant PAR values for various wound aetiologies, such that: p<0.0001 for diabetic foot ulcers (n=11); venous leg ulcers (n=48); pressure ulcers (n=73); and wounds classified as 'other' (n=39). Surgical wounds (n=13) demonstrated a p<0.0007. The study allograft was well-tolerated, with no adverse events directly attributable to the product. Application of the full-thickness allograft as an adjunct to SoC presents a promising option for supporting wound size regression in complex, hard-to-heal wounds.31:T97b, Objective: Management of complex hard-to-heal (chronic) wounds presents a substantial challenge in various healthcare settings where logistical constraints and patient-related factors can impede wound closure. This retrospective study evaluates outcomes associated with the use of a dehydrated, full-thickness placental allograft (CompleteFT; ExtremityCare, LLC, US) composed of the amnion, chorion and intermediate layers, when applied to complex hard-to-heal wounds in a mobile care environment. Method: A retrospective analysis reviewed data collected between February 2024 and July 2025 from patients (aged ≥18 years) with complex hard-to-heal wounds. Data were retrieved from a single mobile wound care service provider team (Compassionate Care Concierge, US). Prior to allograft application, all wounds exhibited stalled healing for at least 30 days with standard of care (SoC). The allograft was applied to all wounds as an adjunct to SoC. Trend changes in wound surface area and percentage area reduction (PAR) across various wound aetiologies were assessed, with additional endpoints including the number of allograft applications and relevant patient parameters. Results: The patient cohort (n=114, with a total of 184 hard-to-heal wounds), included 51 males and 63 females, with a mean age of 73.1 years. Analysis revealed statistically significant PAR values for various wound aetiologies, such that: p<0.0001 for diabetic foot ulcers (n=11); venous leg ulcers (n=48); pressure ulcers (n=73); and wounds classified as ‘other’ (n=39). Surgical wounds (n=13) demonstrated a p<0.0007. The study allograft was well-tolerated, with no adverse events directly attributable to the product. Conclusion: Application of the full-thickness allograft as an adjunct to SoC presents a promising option for supporting wound size regression in complex, hard-to-heal wounds. 25:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Placental Allograft: modality Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Placental Allograft (modality). Clinician-written summaries and actionable practice insights. 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Data were retrieved from a single mobile wound care service provider team (Compassionate Care Concierge, US). Prior to allograft application, all wounds exhibited stalled healing for at least 30 days with standard of care (SoC). The allograft was applied to all wounds as an adjunct to SoC. Trend changes in wound surface area and percentage area reduction (PAR) across various wound aetiologies were assessed, with additional endpoints including the number of allograft applications and relevant patient parameters.","results":"The patient cohort (n=114, with a total of 184 hard-to-heal wounds), included 51 males and 63 females, with a mean age of 73.1 years. Analysis revealed statistically significant PAR values for various wound aetiologies, such that: p<0.0001 for diabetic foot ulcers (n=11); venous leg ulcers (n=48); pressure ulcers (n=73); and wounds classified as 'other' (n=39). Surgical wounds (n=13) demonstrated a p<0.0007. The study allograft was well-tolerated, with no adverse events directly attributable to the product.","abstract":"$30","keywords":["CompleteFT","amniotic membrane","chronic wounds","complex wounds","full-thickness membrane","hard-to-heal","placental allograft","wound","wound care","wound closure","wound covering","wound dressing"],"pubmed_id":"41205152","conclusions":"Application of the full-thickness allograft as an adjunct to SoC presents a promising option for supporting wound size regression in complex, hard-to-heal wounds.","publication_date":"2025-11-08T00:00:00"},"crossref":{"DOI":"10.12968/jowc.2025.0459","URL":"https://doi.org/10.12968/jowc.2025.0459","ISSN":["0969-0700","2052-2916"],"link":[{"URL":"http://www.magonlinelibrary.com/doi/pdf/10.12968/jowc.2025.0459","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":"S15-S24","type":"journal-article","issue":"S11a","score":1,"title":["Application of a full-thickness placental allograft in complex wound management: a case series across diverse aetiologies"],"author":[{"given":"Kirk","family":"Mitchell","sequence":"first","affiliation":[{"name":"Compassionate Concierge Physicians, Longmont, CO, US"}]}],"issued":{"date-parts":[[2025,11,1]]},"member":"5130","prefix":"10.12968","source":"Crossref","volume":"34","created":{"date-time":"2025-10-22T12:15:23Z","timestamp":1761135323000,"date-parts":[[2025,10,22]]},"indexed":{"date-time":"2025-11-11T11:43:29Z","timestamp":1762861409672,"date-parts":[[2025,11,11]]},"subject":[],"abstract":"$31","language":"en","relation":{},"resource":{"primary":{"URL":"http://www.magonlinelibrary.com/doi/10.12968/jowc.2025.0459"}},"subtitle":[],"deposited":{"date-time":"2025-11-11T11:39:30Z","timestamp":1762861170000,"date-parts":[[2025,11,11]]},"issn-type":[{"type":"print","value":"0969-0700"},{"type":"electronic","value":"2052-2916"}],"published":{"date-parts":[[2025,11,1]]},"publisher":"Mark Allen 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time-to-healing are not reported in the abstract; only p-values by etiology.","value_numeric":null},{"paper_doi":"10.12968/jowc.2025.0459","tag_type":"warning","value":"Generalisability may be limited due to setting and a heterogeneous ‘other’ wound category.","value_numeric":null},{"paper_doi":"10.12968/jowc.2025.0459","tag_type":"warning","value":"Uncontrolled case series from a single mobile provider; no comparator described.","value_numeric":null}],"summaries":{"what_studied":"A retrospective case series (Feb 2024–July 2025) from a single US mobile wound care service evaluated a dehydrated, full-thickness placental allograft (CompleteFT) added to standard care in adults (≥18) with complex wounds stalled ≥30 days. Outcomes included trends in wound surface area and percentage area reduction (PAR) by wound etiology.","key_result":"Among 114 patients with 184 wounds (mean age 73.1; 51 male, 63 female), PAR was statistically significant for diabetic foot ulcers (n=11), venous leg ulcers (n=48), pressure ulcers (n=73), and ‘other’ wounds (n=39) with p<0.0001, and for surgical wounds (n=13) with p<0.0007; no adverse events were directly attributed to the product.","limitations":"Retrospective, single-provider case series without a control group and with heterogeneous wound types. The abstract reports p-values but not PAR magnitudes or time-to-closure.","practice_takeaway":"Adjunct use of a full-thickness placental allograft was associated with wound size regression across several chronic wound etiologies and appeared well tolerated, but the uncontrolled design and absent effect sizes limit clinical inference."}}],"initialOffset":1,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"modality","value":"Placental Allograft"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Modalities","href":"/hub/tag/modality"},{"name":"Placental Allograft"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"modality","hub_tag_value":"Placental Allograft"}}}]]

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