2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:T826,Protein-energy wasting, chronic inflammation, and functional decline are prevalent among patients undergoing haemodialysis (HD) and are associated with adverse outcomes and reduced quality of life. Although a substantial body of literature exists on nutritional management in HD, evidence has evolved considerably in recent years. Nutritional care in HD remains inconsistent and is limited by restrictive dietary paradigms and organizational barriers. To map evidence published between 2015 and 2025 on nutritional management in adult patients undergoing HD, focusing on personalized strategies, barriers to effective nutritional care, and patient-centred, function-oriented implementation. A scoping review was conducted following Joanna Briggs Institute methodology and reported according to PRISMA Extension for Scoping Reviews. PubMed/MEDLINE, Scopus, Web of Science, and Europe PMC were searched for English-language studies published between January 2015 and August 2025. A total of 30 studies were included. The literature describes diverse personalized nutritional approaches, including oral and intradialytic supplementation, plant-forward dietary patterns, microbiota-oriented strategies, and targeted nutrient supplementation. Reported outcomes included nutritional biomarkers, inflammation, body composition, functional measures, and patient-reported experience. Key barriers to effective nutritional care were poor dietary adherence, psychosocial burden, limited health literacy, inconsistent professional guidance, and organizational constraints. Morphofunctional assessment tools provided added value beyond biochemical parameters, and the studies highlighted specific considerations for nutritional risk assessment in older adults undergoing HD. This scoping review highlights a shift towards more personalized and function-oriented nutritional care in HD, while underscoring persistent barriers and substantial evidence heterogeneity. The findings support future research and the development of more integrated, patient-centred, and sustainable nutritional care models.31:Tb3a,ABSTRACT Background Protein-energy wasting, chronic inflammation, and functional decline are prevalent among patients undergoing haemodialysis (HD) and are associated with adverse outcomes and reduced quality of life. Although a substantial body of literature exists on nutritional management in HD, evidence has evolved considerably in recent years. Nutritional care in HD remains inconsistent and is limited by restrictive dietary paradigms and organizational barriers. Objective To map evidence published between 2015 and 2025 on nutritional management in adult patients undergoing HD, focusing on personalized strategies, barriers to effective nutritional care, and patient-centred, function-oriented implementation. Methods A scoping review was conducted following Joanna Briggs Institute methodology and reported according to PRISMA Extension for Scoping Reviews. PubMed/MEDLINE, Scopus, Web of Science, and Europe PMC were searched for English-language studies published between January 2015 and August 2025. Results A total of 30 studies were included. The literature describes diverse personalized nutritional approaches, including oral and intradialytic supplementation, plant-forward dietary patterns, microbiota-oriented strategies, and targeted nutrient supplementation. Reported outcomes included nutritional biomarkers, inflammation, body composition, functional measures, and patient-reported experience. Key barriers to effective nutritional care were poor dietary adherence, psychosocial burden, limited health literacy, inconsistent professional guidance, and organizational constraints. Morphofunctional assessment tools provided added value beyond biochemical parameters, and the studies highlighted specific considerations for nutritional risk assessment in older adults undergoing HD. Conclusions This scoping review highlights a shift towards more personalized and function-oriented nutritional care in HD, while underscoring persistent barriers and substantial evidence heterogeneity. The findings support future research and the development of more integrated, patient-centred, and sustainable nutritional care models. 32:T6f6,Coronary microvascular dysfunction (CMD) is associated with adverse cardiovascular outcomes. CMD is driven by endothelial and vascular smooth muscle cell (VSMC) dysfunction. We aimed to test whether CMD could be mitigated by a plant-based diet (PBD) in an animal model of hypertension. We compared 28- and 40-week-old female normotensive Wistar-Kyoto and spontaneously hypertensive rats (SHRs), maintained, from age 4 weeks, on a control refined diet or a PBD, composed of 28% fruits, vegetables, nuts, and legumes. A subset of control SHRs was switched to the PBD at 28 weeks. CMD was assessed by coronary flow reserve via echocardiogram. Cardiac microvascular endothelial function was assessed via cardiac magnetic resonance imaging. Endothelial and VSMC function were assessed in the left ventricle or in isolated VSMCs. The role of gut microbiota was probed via 16S sequencing and antibiotics. Cardiac inflammation, oxidative stress, and fibrosis were also explored. SHRs exhibited endothelial dysfunction and likely VSMC dysfunction. A PBD did not ameliorate their hypertension but, nonetheless, prevented and reversed CMD. The PBD's mitigation of CMD was associated with improved endothelial nitric oxide synthase function and nitric oxide-mediated VSMC signaling, as well as reductions in left ventricular oxidative stress, inflammatory signaling, and fibrosis. A PBD altered the gut microbiota, although antibiotic studies failed to establish its importance in ameliorating CMD. A PBD prevented CMD development and reversed established CMD in SHRs. Such benefits of PBD, which occurred without alleviating hypertension, were possibly due to improved endothelial function and likely improved VSMC function. These results support clinical trials to test PBDs in human CMD.33:T9bd, Background Coronary microvascular dysfunction (CMD) is associated with adverse cardiovascular outcomes. CMD is driven by endothelial and vascular smooth muscle cell (VSMC) dysfunction. We aimed to test whether CMD could be mitigated by a plant‐based diet (PBD) in an animal model of hypertension. Methods We compared 28‐ and 40‐week‐old female normotensive Wistar–Kyoto and spontaneously hypertensive rats (SHRs), maintained, from age 4 weeks, on a control refined diet or a PBD, composed of 28% fruits, vegetables, nuts, and legumes. A subset of control SHRs was switched to the PBD at 28 weeks. CMD was assessed by coronary flow reserve via echocardiogram. Cardiac microvascular endothelial function was assessed via cardiac magnetic resonance imaging. Endothelial and VSMC function were assessed in the left ventricle or in isolated VSMCs. The role of gut microbiota was probed via 16S sequencing and antibiotics. Cardiac inflammation, oxidative stress, and fibrosis were also explored. Results SHRs exhibited endothelial dysfunction and likely VSMC dysfunction. A PBD did not ameliorate their hypertension but, nonetheless, prevented and reversed CMD. The PBD’s mitigation of CMD was associated with improved endothelial nitric oxide synthase function and nitric oxide–mediated VSMC signaling, as well as reductions in left ventricular oxidative stress, inflammatory signaling, and fibrosis. A PBD altered the gut microbiota, although antibiotic studies failed to establish its importance in ameliorating CMD. Conclusions A PBD prevented CMD development and reversed established CMD in SHRs. Such benefits of PBD, which occurred without alleviating hypertension, were possibly due to improved endothelial function and likely improved VSMC function. These results support clinical trials to test PBDs in human CMD. 25:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Plant-Based Diet: modality Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Plant-Based Diet (modality). Clinician-written summaries and actionable practice insights. Updated daily.\",\"url\":\"https://www.reachrx.ai/hub/tag/modality/Plant-Based%20Diet\",\"breadcrumb\":{\"@type\":\"BreadcrumbList\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https://www.reachrx.ai\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research Hub\",\"item\":\"https://www.reachrx.ai/hub\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Modalities\",\"item\":\"https://www.reachrx.ai/hub/tag/modality\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Plant-Based Diet\",\"item\":\"https://www.reachrx.ai/hub/tag/modality/Plant-Based%20Diet\"}]}}"}}]],["$","$L2f",null,{"title":"Plant-Based Diet: Research & Clinical Takeaways","description":"Review evidence by treatment modality: Plant-Based Diet — concise summaries and practical next steps.","papers":[{"doi":"10.1182/bloodadvances.2026020270","pmid":"42263665","title":"Plant-based whole-food diets are feasible during auto-HCT and are associated with dose-dependent microbiome modulation","journal_title":"Blood Advances","journal_issn":"2473-9529","published_at":"2026-06-09T00:00:00.000Z","url":"https://doi.org/10.1182/bloodadvances.2026020270","source_score":8,"is_retracted":false,"is_open_access":true,"raw_metadata":{"pubmed":true,"crossref":true,"unpaywall":true},"created_at":"2026-08-20T06:48:02.141Z","updated_at":"2026-08-20T06:48:02.141Z","tags":[{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"category","value":"Hematology","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"condition","value":"Intestinal Dysbiosis","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"condition","value":"Multiple Myeloma","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"impact_flag","value":"limited_evidence","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"level_of_evidence","value":"3","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"modality","value":"Dietary Intervention","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"modality","value":"Plant-Based Diet","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"sample_size","value":"n=22","value_numeric":22},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"sex","value":"mixed","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"study_design","value":"Single-Arm Clinical Trial","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"warning","value":"No control arm was included; observed microbiome changes cannot be attributed solely to the intervention versus transplant-related effects.","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"warning","value":"Nutrient-microbiome correlations (including fiber) did not survive Benjamini-Hochberg correction across all tests — reported associations are nominally significant only.","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"warning","value":"Quality-of-life outcomes (EORTC QLQ-C30/MY20) showed mixed signals (e.g., worsened global QoL, worsened constipation and pain, improved fatigue and appetite) but are reported descriptively without statistical testing.","value_numeric":null},{"paper_doi":"10.1182/bloodadvances.2026020270","tag_type":"warning","value":"The full paper text was not provided; only the abstract and supplementary methods/figures were available — some details may be missing or underrepresented.","value_numeric":null}],"summaries":{"what_studied":"A single-arm trial (n=22) tested a 5-week plant-based whole-food meal delivery intervention in multiple myeloma patients undergoing auto-HCT, spanning conditioning, neutropenia, and early recovery. Primary endpoints were feasibility and tolerability; secondary endpoints included gut microbiome composition (shotgun metagenomics) and fecal short-chain fatty acid (SCFA) levels.","key_result":"All 22 enrolled participants consumed study meals to some degree (17/22 completed the full study). Higher meal intake was dose-dependently associated with enrichment of SCFA-producing taxa (e.g., Blautia, Lachnospiraceae) and fiber-responsive microbiome shifts. Fecal SCFA concentrations increased from baseline to end of study. Fiber was the most prominent differentially consumed nutrient in high vs. low consumers.","limitations":"- Single-arm design with no control group limits causal inference about microbiome or clinical outcomes.\n- Small sample size (n=22) limits statistical power; nutrient-microbiome correlations did not survive multiple-testing correction.\n- Study meals were commercially prepared ('Thistle'), limiting generalizability to other plant-based approaches or settings.","practice_takeaway":"A structured plant-based meal delivery program appears feasible and well tolerated during auto-HCT for multiple myeloma, with adherence supporting measurable microbiome changes. Clinicians may consider dietary fiber optimization as a low-risk adjunct strategy during transplant, pending controlled trial data."}},{"doi":"10.1093/ckj/sfag117","pmid":"42094027","title":"Personalized nutrition in haemodialysis: a scoping review of studies published between 2015 and 2025","journal_title":"Clinical Kidney Journal","journal_issn":"2048-8505","published_at":"2026-05-07T00:00:00.000Z","url":"https://doi.org/10.1093/ckj/sfag117","source_score":42,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2026-04-19","doi":"10.1093/ckj/sfag117","days":"30","issn":"2048-8505","rank":"5","field":"Clinical Medicine","score":"42","category":"Urology & Nephrology","categories":["Urology & Nephrology"],"_categories":["Urology & Nephrology"]},"pubmed":{"doi":"10.1093/ckj/sfag117","title":"Personalized nutrition in haemodialysis: a scoping review of studies published between 2015 and 2025.","journal":"Clinical kidney journal","methods":"","results":"A total of 30 studies were included. The literature describes diverse personalized nutritional approaches, including oral and intradialytic supplementation, plant-forward dietary patterns, microbiota-oriented strategies, and targeted nutrient supplementation. Reported outcomes included nutritional biomarkers, inflammation, body composition, functional measures, and patient-reported experience. Key barriers to effective nutritional care were poor dietary adherence, psychosocial burden, limited health literacy, inconsistent professional guidance, and organizational constraints. Morphofunctional assessment tools provided added value beyond biochemical parameters, and the studies highlighted specific considerations for nutritional risk assessment in older adults undergoing HD.","abstract":"$30","keywords":["dietary adherence","haemodialysis","morphofunctional nutritional assessment","patient-centred care","personalized nutrition","protein-energy wasting"],"pubmed_id":"42094027","conclusions":"","publication_date":"2026-05-07T00:00:00"},"crossref":{"DOI":"10.1093/ckj/sfag117","URL":"https://doi.org/10.1093/ckj/sfag117","ISSN":["2048-8505","2048-8513"],"link":[{"URL":"https://academic.oup.com/ckj/advance-article-pdf/doi/10.1093/ckj/sfag117/68093728/sfag117.pdf","content-type":"application/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https://academic.oup.com/ckj/article-pdf/19/5/sfag117/68093728/sfag117.pdf","content-type":"application/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https://academic.oup.com/ckj/article-pdf/19/5/sfag117/68093728/sfag117.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":null,"type":"journal-article","issue":"5","score":1,"title":["Personalized nutrition in haemodialysis: a scoping review of studies published between 2015 and 2025"],"author":[{"given":"José Francisco","family":"Rojas-Pérez","sequence":"first","affiliation":[{"name":"Diaverum Málaga , Málaga ,"}]},{"given":"Sheila","family":"González-Salvatierra","sequence":"additional","affiliation":[{"name":"IBIMA Plataforma BIONAND, Instituto de Investigación Biomédica de Málaga , Málaga ,"},{"name":"Hospital Regional Universitario de Málaga Department of Endocrinology and Nutrition, , Málaga ,"},{"name":"Instituto de Salud Carlos III, CIBER of Frailty and Healthy Aging (CIBERFES) , Madrid ,"}]},{"given":"Alejandro","family":"Oncina-Cánovas","sequence":"additional","affiliation":[{"name":"Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL) , Alicante ,"},{"name":"Universidad Miguel Hernández (UMH) Unidad de Epidemiología de la Nutrición, Departamento de Salud Pública, Historia de la Ciencia y Ginecología, , Alicante ,"},{"name":"Instituto de Salud Carlos III, CIBER of Epidemiology and Public Health (CIBERESP) , Madrid ,"}]},{"given":"Marina","family":"Padial","sequence":"additional","affiliation":[{"name":"IBIMA Plataforma BIONAND, Instituto de Investigación Biomédica de Málaga , Málaga ,"},{"name":"Hospital Regional Universitario de Málaga Department of Endocrinology and Nutrition, , Málaga ,"},{"name":"University of Málaga Department of Medicine and Dermatology, , Málaga ,"}]},{"given":"Verónica","family":"López-Jiménez","sequence":"additional","affiliation":[{"name":"IBIMA Plataforma BIONAND, Instituto de Investigación Biomédica de Málaga , Málaga ,"},{"name":"University of Málaga Department of Medicine and Dermatology, , Málaga ,"},{"name":"Hospital Regional Universitario de Málaga Department of Nephrology, , Málaga ,"},{"name":"Instituto de Salud Carlos III, National Network for Kidney Research RICORS2040 RD21/0005/0012 , Madrid ,"}]},{"given":"Gabriel","family":"Olveira","sequence":"additional","affiliation":[{"name":"IBIMA Plataforma BIONAND, Instituto de Investigación Biomédica de Málaga , Málaga ,"},{"name":"Hospital Regional Universitario de Málaga Department of Endocrinology and Nutrition, , Málaga ,"},{"name":"University of Málaga Department of Medicine and Dermatology, , Málaga ,"},{"name":"Instituto de Salud Carlos III, CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM) , Madrid ,"}]}],"funder":[{"id":[{"id":"10.13039/501100004587","id-type":"DOI","asserted-by":"publisher"}],"DOI":"10.13039/501100004587","name":"Institute of Health Carlos III","award":["CD24/00003"],"award-info":[{"award-number":["CD24/00003"]}],"doi-asserted-by":"publisher"},{"id":[{"id":"10.13039/100009473","id-type":"DOI","asserted-by":"publisher"}],"DOI":"10.13039/100009473","name":"Universidad de Málaga","doi-asserted-by":"publisher"}],"issued":{"date-parts":[[2026,4,16]]},"member":"286","prefix":"10.1093","source":"Crossref","volume":"19","created":{"date-time":"2026-04-15T11:39:25Z","timestamp":1776253165000,"date-parts":[[2026,4,15]]},"indexed":{"date-time":"2026-05-05T15:13:07Z","timestamp":1777993987496,"date-parts":[[2026,5,5]]},"license":[{"URL":"https://creativecommons.org/licenses/by/4.0/","start":{"date-time":"2026-04-16T00:00:00Z","timestamp":1776297600000,"date-parts":[[2026,4,16]]},"delay-in-days":0,"content-version":"vor"}],"subject":[],"abstract":"$31","language":"en","relation":{},"resource":{"primary":{"URL":"https://academic.oup.com/ckj/article/doi/10.1093/ckj/sfag117/8655904"}},"subtitle":[],"deposited":{"date-time":"2026-05-05T14:41:55Z","timestamp":1777992115000,"date-parts":[[2026,5,5]]},"issn-type":[{"type":"print","value":"2048-8505"},{"type":"electronic","value":"2048-8513"}],"published":{"date-parts":[[2026,4,16]]},"publisher":"Oxford University Press (OUP)","reference":[{"DOI":"10.1111/dom.15683","key":"2026050510414863300_bib1","year":"2024","issue":null,"author":"Selby","volume":"26","first-page":"3","unstructured":null,"article-title":"What every clinician needs to know about chronic kidney disease: detection, classification and epidemiology","journal-title":"Diabetes Obes Metab","doi-asserted-by":"publisher"},{"DOI":"10.1016/S0140-6736(16)32064-5","key":"2026050510414863300_bib2","year":"2017","issue":null,"author":"Webster","volume":"389","first-page":"1238","unstructured":null,"article-title":"Chronic kidney disease","journal-title":"The Lancet","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.kint.2019.07.012","key":"2026050510414863300_bib3","year":"2019","issue":null,"author":"Jager","volume":"96","first-page":"1048","unstructured":null,"article-title":"A single number for advocacy and communication-worldwide more than 850 million individuals have kidney diseases","journal-title":"Kidney Int","doi-asserted-by":"publisher"},{"DOI":"10.1016/S0140-6736(16)31012-1","key":"2026050510414863300_bib4","year":"2016","issue":null,"author":"GBD 2015 Mortality and Causes of Death Collaborators","volume":"388","first-page":"1459","unstructured":null,"article-title":"Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015","journal-title":"The Lancet","doi-asserted-by":"publisher"},{"DOI":"10.1038/s41581-022-00542-7","key":"2026050510414863300_bib5","year":"2022","issue":null,"author":"Bello","volume":"18","first-page":"378","unstructured":null,"article-title":"Epidemiology of haemodialysis outcomes","journal-title":"Nat Rev Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1001/jama.2024.16338","key":"2026050510414863300_bib6","year":"2024","issue":null,"author":"Flythe","volume":"332","first-page":"1559","unstructured":null,"article-title":"Dialysis for chronic kidney failure: a review","journal-title":"JAMA","doi-asserted-by":"publisher"},{"DOI":"10.1038/s41581-018-0002-x","key":"2026050510414863300_bib7","year":"2018","issue":null,"author":"Ronco","volume":"14","first-page":"394","unstructured":null,"article-title":"Haemodialysis membranes","journal-title":"Nat Rev Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1111/sdi.12659","key":"2026050510414863300_bib8","year":"2018","issue":null,"author":"Qian","volume":"31","first-page":"226","unstructured":null,"article-title":"Acid–base alterations in ESRD and effects of hemodialysis","journal-title":"Semin Dial","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.ajkd.2017.03.015","key":"2026050510414863300_bib9","year":"2017","issue":null,"author":"Hanudel","volume":"70","first-page":"445","unstructured":null,"article-title":"Fractures and osteomalacia in a patient treated with frequent home hemodialysis","journal-title":"Am J Kidney Dis","doi-asserted-by":"publisher"},{"DOI":"10.1111/sdi.12704","key":"2026050510414863300_bib10","year":"2018","issue":null,"author":"Kooman","volume":"31","first-page":"500","unstructured":null,"article-title":"Hemodialysis: a model for extreme physiology in a vulnerable patient population","journal-title":"Semin Dial","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2018.08.006","key":"2026050510414863300_bib11","year":"2018","issue":null,"author":"Carrero","volume":"28","first-page":"380","unstructured":null,"article-title":"Global prevalence of protein-energy wasting in kidney disease: a meta-analysis of contemporary observational studies from the International Society of Renal Nutrition and Metabolism","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu12103147","key":"2026050510414863300_bib12","year":"2020","issue":null,"author":"Sahathevan","volume":"12","first-page":"3147","unstructured":null,"article-title":"Understanding development of malnutrition in hemodialysis patients: a narrative review","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.clinbiochem.2017.09.012","key":"2026050510414863300_bib13","year":"2017","issue":null,"author":"Zhang","volume":"50","first-page":"1078","unstructured":null,"article-title":"Removal of uremic retention products by hemodialysis is coupled with indiscriminate loss of vital metabolites","journal-title":"Clin Biochem","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2018.01.016","key":"2026050510414863300_bib14","year":"2018","issue":null,"author":"Salame","volume":"28","first-page":"317","unstructured":null,"article-title":"Protein losses and urea nitrogen underestimate total nitrogen losses in peritoneal dialysis and hemodialysis patients","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1093/ndt/gfx191","key":"2026050510414863300_bib15","year":"2018","issue":null,"author":"van Gelder","volume":"33","first-page":"906","unstructured":null,"article-title":"Albumin handling in different hemodialysis modalities","journal-title":"Nephrol Dial Transplant","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu14173454","key":"2026050510414863300_bib16","year":"2022","issue":null,"author":"Bévier","volume":"14","first-page":"3454","unstructured":null,"article-title":"Water-soluble vitamins and trace elements losses during on-line hemodiafiltration","journal-title":"Nutrients","doi-asserted-by":"crossref"},{"DOI":"10.1053/j.jrn.2012.08.009","key":"2026050510414863300_bib17","year":"2013","issue":null,"author":"Lynch","volume":"23","first-page":"288","unstructured":null,"article-title":"Altered taste perception and nutritional status among hemodialysis patients","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.3945/jn.114.206029","key":"2026050510414863300_bib18","year":"2015","issue":null,"author":"Ronveaux","volume":"145","first-page":"672","unstructured":null,"article-title":"Glucagon-like peptide 1 interacts with ghrelin and leptin to regulate glucose metabolism and food intake through vagal afferent neuron signaling","journal-title":"J Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1111/nep.13243","key":"2026050510414863300_bib19","year":"2018","issue":null,"author":"Zuvela","volume":"23","first-page":"718","unstructured":null,"article-title":"Gastrointestinal symptoms in patients receiving dialysis: a systematic review","journal-title":"Nephrology","doi-asserted-by":"publisher"},{"DOI":"10.5812/numonthly.23158","key":"2026050510414863300_bib20","year":"2014","issue":null,"author":"Ekramzadeh","volume":"6","first-page":"e23158","unstructured":null,"article-title":"Major barriers responsible for malnutrition in hemodialysis patients: challenges to optimal nutrition","journal-title":"Nephro Urol Mon","doi-asserted-by":"publisher"},{"DOI":"10.19082/4820","key":"2026050510414863300_bib21","year":"2017","issue":null,"author":"Kiajamali","volume":"9","first-page":"4820","unstructured":null,"article-title":"Correlation between social support, self-efficacy and health-promoting behavior in hemodialysis patients hospitalized in Karaj in 2015","journal-title":"Electron Physician","doi-asserted-by":"publisher"},{"DOI":"10.1093/ndt/17.suppl_11.28","key":"2026050510414863300_bib22","year":"2002","issue":null,"author":"Pecoits-Filho","volume":"17","first-page":"28","unstructured":null,"article-title":"The malnutrition, inflammation, and atherosclerosis (MIA) syndrome—the heart of the matter","journal-title":"Nephrol Dial Transplant","doi-asserted-by":"publisher"},{"DOI":"10.1038/s41598-020-80716-0","key":"2026050510414863300_bib23","year":"2021","issue":null,"author":"Kanda","volume":"11","first-page":"1582","unstructured":null,"article-title":"The combination of malnutrition-inflammation and functional status limitations is associated with mortality in hemodialysis patients","journal-title":"Sci Rep","doi-asserted-by":"publisher"},{"DOI":"10.1111/sdi.12686","key":"2026050510414863300_bib24","year":"2018","issue":null,"author":"Nowak","volume":"31","first-page":"388","unstructured":null,"article-title":"Does inflammation affect outcomes in dialysis patients?","journal-title":"Semin Dial","doi-asserted-by":"publisher"},{"DOI":"10.1038/s41598-024-72218-0","key":"2026050510414863300_bib25","year":"2024","issue":null,"author":"Li","volume":"14","first-page":"21169","unstructured":null,"article-title":"Association of visceral adiposity index with sarcopenia based on NHANES data","journal-title":"Sci Rep","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2016.09.010","key":"2026050510414863300_bib26","year":"2017","issue":null,"author":"Malhotra","volume":"27","first-page":"84","unstructured":null,"article-title":"Sarcopenic obesity definitions by body composition and mortality in the hemodialysis patients","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.7570/jomes24013","key":"2026050510414863300_bib27","year":"2024","issue":null,"author":"Blüher","volume":"33","first-page":"275","unstructured":null,"article-title":"Understanding adipose tissue dysfunction","journal-title":"J Obes Metab Syndr","doi-asserted-by":"crossref"},{"DOI":"10.1016/j.ekir.2017.01.009","key":"2026050510414863300_bib28","year":"2017","issue":null,"author":"Kalantar-Zadeh","volume":"2","first-page":"271","unstructured":null,"article-title":"The obesity paradox in kidney disease: how to reconcile it with obesity management","journal-title":"Kidney Int Rep","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu17193034","key":"2026050510414863300_bib29","year":"2025","issue":null,"author":"Andreew-Gamza","volume":"17","first-page":"3034","unstructured":null,"article-title":"Evaluating the associations of adiposity, functional status, and anthropometric measures with nutritional status in chronic hemodialysis patients: a cross-sectional study","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu15030612","key":"2026050510414863300_bib30","year":"2023","issue":null,"author":"García-Almeida","volume":"15","first-page":"612","unstructured":null,"article-title":"Expert consensus on morphofunctional assessment in disease-related malnutrition. Grade review and Delphi study","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu17213478","key":"2026050510414863300_bib31","year":"2025","issue":null,"author":"Arroyo-Serrano","volume":"17","first-page":"3478","unstructured":null,"article-title":"Nutritional strategies to address malnutrition in dialyses patients: a systematic review","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu12030785","key":"2026050510414863300_bib32","year":"2020","issue":null,"author":"Piccoli","volume":"12","first-page":"785","unstructured":null,"article-title":"Intradialytic nutrition and hemodialysis prescriptions: a personalized stepwise approach","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":null,"key":"2026050510414863300_bib33","year":"2025","issue":null,"author":"Pan","volume":"31","first-page":"316","unstructured":null,"article-title":"An analysis of the effects of predictive early nutritional care interventions in patients undergoing maintenance haemodialysis","journal-title":"Altern Ther Health Med","doi-asserted-by":null},{"DOI":"10.1053/j.ajkd.2020.05.006","key":"2026050510414863300_bib34","year":"2020","issue":null,"author":"Ikizler","volume":"76","first-page":"S1","unstructured":null,"article-title":"KDOQI Clinical Practice Guideline for Nutrition in CKD: 2020 update","journal-title":"Am J Kidney Dis","doi-asserted-by":"publisher"},{"DOI":"10.1159/000548114","key":"2026050510414863300_bib35","year":"2025","issue":null,"author":"Zhao","volume":null,"first-page":"1","unstructured":null,"article-title":"Intradialytic exercise interventions to enhance physical activity levels in hemodialysis patients: a systematic review and meta-analysis","journal-title":"Am J Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu16234018","key":"2026050510414863300_bib36","year":"2024","issue":null,"author":"Arias-Guillén","volume":"16","first-page":"4018","unstructured":null,"article-title":"Intradialytic parenteral nutrition in patients on hemodialysis: a multicenter retrospective study","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1111/sdi.12681","key":"2026050510414863300_bib37","year":"2018","issue":null,"author":"Anderson","volume":"31","first-page":"115","unstructured":null,"article-title":"Nutrition education in the care of patients with chronic kidney disease and end-stage renal disease","journal-title":"Semin Dial","doi-asserted-by":"publisher"},{"DOI":"10.3390/biomedicines13030647","key":"2026050510414863300_bib38","year":"2025","issue":null,"author":"Pradhan","volume":"13","first-page":"647","unstructured":null,"article-title":"Personalized nutrition in chronic kidney disease","journal-title":"Biomedicines","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu9040372","key":"2026050510414863300_bib39","year":"2017","issue":null,"author":"Piccoli","volume":"9","first-page":"372","unstructured":null,"article-title":"The diet and haemodialysis dyad: three eras, four open questions and four paradoxes. A narrative review, towards a personalized, patient-centered approach","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu13051390","key":"2026050510414863300_bib40","year":"2021","issue":null,"author":"Kanno","volume":"13","first-page":"1390","unstructured":null,"article-title":"Methods and nutritional interventions to improve the nutritional status of dialysis patients in JAPAN—a narrative review","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1111/sdi.12697","key":"2026050510414863300_bib41","year":"2018","issue":null,"author":"Uribarri","volume":"31","first-page":"236","unstructured":null,"article-title":"An aspirational diet for dialysis patients: evidence and theory","journal-title":"Semin Dial","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.kint.2023.10.018","key":"2026050510414863300_bib42","year":"2024","issue":null,"author":null,"volume":"105","first-page":"S117","unstructured":null,"article-title":"Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease","journal-title":"Kidney Int","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.clnu.2021.01.028","key":"2026050510414863300_bib43","year":"2021","issue":null,"author":"Fiaccadori","volume":"40","first-page":"1644","unstructured":null,"article-title":"ESPEN guideline on clinical nutrition in hospitalized patients with acute or chronic kidney disease","journal-title":"Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.11124/JBIES-20-00167","key":"2026050510414863300_bib44","year":"2020","issue":null,"author":"Peters","volume":"18","first-page":"2119","unstructured":null,"article-title":"Updated methodological guidance for the conduct of scoping reviews","journal-title":"JBI Evid Synth","doi-asserted-by":"publisher"},{"DOI":"10.7326/M18-0850","key":"2026050510414863300_bib45","year":"2018","issue":null,"author":"Tricco","volume":"169","first-page":"467","unstructured":null,"article-title":"PRISMA Extension for Scoping Reviews (PRISMA-ScR): checklist and explanation","journal-title":"Ann Intern Med","doi-asserted-by":"publisher"},{"DOI":"10.1186/s13643-016-0384-4","key":"2026050510414863300_bib46","year":"2016","issue":null,"author":"Ouzzani","volume":"5","first-page":"210","unstructured":null,"article-title":"Rayyan—a web and mobile app for systematic reviews","journal-title":"Syst Rev","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.jclinepi.2007.11.008","key":"2026050510414863300_bib47","year":"2008","issue":null,"author":"von Elm","volume":"61","first-page":"344","unstructured":null,"article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","journal-title":"J Clin Epidemiol","doi-asserted-by":"publisher"},{"DOI":"10.1136/bmj-2024-081123","key":"2026050510414863300_bib48","year":"2025","issue":null,"author":"Hopewell","volume":"389","first-page":"e081123","unstructured":null,"article-title":"CONSORT 2025 statement: updated guideline for reporting randomised trials","journal-title":"BMJ","doi-asserted-by":"crossref"},{"DOI":"10.1136/bmj.j4008","key":"2026050510414863300_bib49","year":"2017","issue":null,"author":"Shea","volume":"358","first-page":"j4008","unstructured":null,"article-title":"AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both","journal-title":"BMJ","doi-asserted-by":"publisher"},{"DOI":"10.1007/s11255-020-02768-5","key":"2026050510414863300_bib50","year":"2021","issue":null,"author":"Limwannata","volume":"53","first-page":"1675","unstructured":null,"article-title":"Effectiveness of renal-specific oral nutritional supplements compared with diet counseling in malnourished hemodialysis patients","journal-title":"Int Urol Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1186/s12882-025-03999-3","key":"2026050510414863300_bib51","year":"2025","issue":null,"author":"Elsayed","volume":"26","first-page":"103","unstructured":null,"article-title":"The impact of predialytic oral protein-based supplements on nutritional status and quality of life in hemodialysis patients: a randomized clinical trial","journal-title":"BMC Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.clnu.2015.11.016","key":"2026050510414863300_bib52","year":"2017","issue":null,"author":"Marsen","volume":"36","first-page":"107","unstructured":null,"article-title":"Intradialytic parenteral nutrition in maintenance hemodialysis patients suffering from protein-energy wasting. Results of a multicenter, open, prospective, randomized trial","journal-title":"Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2023.04.003","key":"2026050510414863300_bib53","year":"2023","issue":null,"author":"Tsai","volume":"33","first-page":"731","unstructured":null,"article-title":"Short-term effects of a therapeutic diet on biochemical parameters in hemodialysis patients: a randomized crossover trial","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1093/ndt/gfaa194","key":"2026050510414863300_bib54","year":"2021","issue":null,"author":"González-Ortiz","volume":"36","first-page":"681","unstructured":null,"article-title":"Nutritional status, hyperkalaemia and attainment of energy/protein intake targets in haemodialysis patients following plant-based diets: a longitudinal cohort study","journal-title":"Nephrol Dial Transplant","doi-asserted-by":"publisher"},{"DOI":null,"key":"2026050510414863300_bib55","year":"2020","issue":null,"author":"Miyoshi","volume":"66","first-page":"E12","unstructured":null,"article-title":"Prebiotics improved the defecation status via changes in the microbiota and short-chain fatty acids in hemodialysis patients","journal-title":"Kobe J Med Sci","doi-asserted-by":null},{"DOI":"10.1053/j.jrn.2022.04.001","key":"2026050510414863300_bib56","year":"2023","issue":null,"author":"Chen","volume":"33","first-page":"126","unstructured":null,"article-title":"Probiotics, prebiotics, and synbiotics for patients on dialysis: a systematic review and meta-analysis of randomized controlled trials","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1080/07315724.2021.1953416","key":"2026050510414863300_bib57","year":"2022","issue":null,"author":"Liu","volume":"41","first-page":"697","unstructured":null,"article-title":"Effects of omega-3 fatty acid intake in patients undergoing dialysis: a systematic review and meta-analysis of randomized controlled trials","journal-title":"J Am Nutr Assoc","doi-asserted-by":"publisher"},{"DOI":"10.3390/ijms252011036","key":"2026050510414863300_bib58","year":"2024","issue":null,"author":"Bogacka","volume":"25","first-page":"11036","unstructured":null,"article-title":"Effects of diet and supplements on parameters of oxidative stress, inflammation, and antioxidant mechanisms in patients with chronic renal failure undergoing hemodialysis","journal-title":"Int J Mol Sci","doi-asserted-by":"publisher"},{"DOI":"10.1371/journal.pone.0328757","key":"2026050510414863300_bib59","year":"2025","issue":null,"author":"Bernales-Delmon","volume":"20","first-page":"e0328757","unstructured":null,"article-title":"Oral creatine in hemodialysis patients increases physical functional capacity and muscle mass, an open label study","journal-title":"PLoS One","doi-asserted-by":"publisher"},{"DOI":"10.1186/s12882-019-1622-5","key":"2026050510414863300_bib60","year":"2019","issue":null,"author":"Gebrie","volume":"20","first-page":"429","unstructured":null,"article-title":"Depressive symptoms and dietary non-adherence among end stage renal disease patients undergoing hemodialysis therapy: systematic review","journal-title":"BMC Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2021.11.007","key":"2026050510414863300_bib61","year":"2022","issue":null,"author":"Vr","volume":"32","first-page":"658","unstructured":null,"article-title":"The worldwide prevalence of nonadherence to diet and fluid restrictions among hemodialysis patients: a systematic review and meta-analysis","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":null,"key":"2026050510414863300_bib62","year":"2021","issue":null,"author":"Hendriks","volume":"24","first-page":"79","unstructured":null,"article-title":"Dietary protein interventions to improve nutritional status in end-stage renal disease patients undergoing hemodialysis","journal-title":"Curr Opin Clin Nutr Metab Care","doi-asserted-by":null},{"DOI":"10.1111/jhn.12472","key":"2026050510414863300_bib63","year":"2017","issue":null,"author":"Rizk","volume":"30","first-page":"554","unstructured":null,"article-title":"Effect of stage-based education provided by dedicated dietitians on hyperphosphataemic haemodialysis patients: results from the Nutrition Education for Management of Osteodystrophy randomised controlled trial","journal-title":"J Hum Nutr Diet","doi-asserted-by":"publisher"},{"DOI":"10.1111/jocn.13804","key":"2026050510414863300_bib64","year":"2017","issue":null,"author":"Oquendo","volume":"26","first-page":"3893","unstructured":null,"article-title":"Contributing factors for therapeutic diet adherence in patients receiving haemodialysis treatment: an integrative review","journal-title":"J Clin Nurs","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2024.08.005","key":"2026050510414863300_bib65","year":"2025","issue":null,"author":"Padial","volume":"35","first-page":"337","unstructured":null,"article-title":"Dietary needs, barriers, and facilitators among patients on hemodialysis and their caregivers: the GoodRENal Project in Spain","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu13072299","key":"2026050510414863300_bib66","year":"2021","issue":null,"author":"McLean","volume":"13","first-page":"2299","unstructured":null,"article-title":"Experiences of New Zealand haemodialysis patients in relation to food and nutrition management: a qualitative study","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1111/jocn.16910","key":"2026050510414863300_bib67","year":"2024","issue":null,"author":"Mesa-Gresa","volume":"33","first-page":"1062","unstructured":null,"article-title":"Needs, barriers and facilitators for a healthier lifestyle in haemodialysis patients: the GoodRENal project","journal-title":"J Clin Nurs","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2016.06.001","key":"2026050510414863300_bib68","year":"2017","issue":null,"author":"Biruete","volume":"27","first-page":"62","unstructured":null,"article-title":"Modified nutritional recommendations to improve dietary patterns and outcomes in hemodialysis patients","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1097/MD.0000000000041592","key":"2026050510414863300_bib69","year":"2025","issue":null,"author":"Zhang","volume":"104","first-page":"e41592","unstructured":null,"article-title":"Research progress on influencing factors and intervention methods of protein-energy wasting in maintenance hemodialysis patients: a literature review","journal-title":"Medicine (Baltimore)","doi-asserted-by":"publisher"},{"DOI":"10.1371/journal.pone.0317132","key":"2026050510414863300_bib70","year":"2025","issue":null,"author":"Hamdan","volume":"20","first-page":"e0317132","unstructured":null,"article-title":"Factors associated with malnutrition inflammation score among hemodialysis patients: a cross-sectional investigation in tertiary care hospital, Palestine","journal-title":"PLoS One","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.clnu.2018.05.004","key":"2026050510414863300_bib71","year":"2019","issue":null,"author":"Sabatino","volume":"38","first-page":"1232","unstructured":null,"article-title":"Noninvasive evaluation of muscle mass by ultrasonography of quadriceps femoris muscle in End-Stage Renal Disease patients on hemodialysis","journal-title":"Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.clnu.2020.07.025","key":"2026050510414863300_bib72","year":"2021","issue":null,"author":"Matsuzawa","volume":"40","first-page":"1161","unstructured":null,"article-title":"The clinical applicability of ultrasound technique for diagnosis of sarcopenia in hemodialysis patients","journal-title":"Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.3390/jcm12062113","key":"2026050510414863300_bib73","year":"2023","issue":null,"author":"Ishida","volume":"12","first-page":"2113","unstructured":null,"article-title":"Recent advances in the nutritional screening, assessment, and treatment of Japanese patients on hemodialysis","journal-title":"JCM","doi-asserted-by":"publisher"},{"DOI":"10.1093/ndt/gfw471","key":"2026050510414863300_bib74","year":"2017","issue":null,"author":"Rodrigues","volume":"32","first-page":"1780","unstructured":null,"article-title":"Nutritional assessment of elderly patients on dialysis: pitfalls and potentials for practice","journal-title":"Nephrol Dial Transplant","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.nut.2017.03.013","key":"2026050510414863300_bib75","year":"2017","issue":null,"author":"Martins","volume":"41","first-page":"73","unstructured":null,"article-title":"Elderly patients on hemodialysis have worse dietary quality and higher consumption of ultraprocessed food than elderly without chronic kidney disease","journal-title":"Nutrition","doi-asserted-by":"publisher"},{"DOI":"10.1186/s12882-017-0734-z","key":"2026050510414863300_bib76","year":"2017","issue":null,"author":"Lambert","volume":"18","first-page":"318","unstructured":null,"article-title":"An integrative review of the methodology and findings regarding dietary adherence in end stage kidney disease","journal-title":"BMC Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1080/16070658.2020.1751415","key":"2026050510414863300_bib77","year":"2021","issue":null,"author":"Spies","volume":"34","first-page":"116","unstructured":null,"article-title":"Knowledge, attitude and practices of patients receiving maintenance haemodialysis in Bloemfontein","journal-title":"South Afr J Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1038/s41598-024-72366-3","key":"2026050510414863300_bib78","year":"2024","issue":null,"author":"Peng","volume":"14","first-page":"21825","unstructured":null,"article-title":"Knowledge, attitude, and practice toward nutrition support and management among hemodialysis patients","journal-title":"Sci Rep","doi-asserted-by":"publisher"},{"DOI":"10.3390/ijerph17207479","key":"2026050510414863300_bib79","year":"2020","issue":null,"author":"Lim","volume":"17","first-page":"7479","unstructured":null,"article-title":"Understanding how nutrition literacy links to dietary adherence in patients undergoing maintenance hemodialysis: a theoretical exploration using partial least squares structural equation modeling","journal-title":"Int J Environ Res Public Health","doi-asserted-by":"publisher"},{"DOI":"10.1186/s12889-024-18066-z","key":"2026050510414863300_bib80","year":"2024","issue":null,"author":"Chen","volume":"24","first-page":"836","unstructured":null,"article-title":"Dietary knowledge-attitude-practice status in hemodialysis patients: a latent profile analysis","journal-title":"BMC Public Health","doi-asserted-by":"publisher"},{"DOI":"10.1111/hex.70000","key":"2026050510414863300_bib81","year":"2024","issue":null,"author":"Andersen-Hollekim","volume":"27","first-page":"e70000","unstructured":null,"article-title":"Exploring healthcare paradoxes in hospital haemodialysis—a qualitative study","journal-title":"Health Expect","doi-asserted-by":"publisher"},{"DOI":"10.1177/0884533611419665","key":"2026050510414863300_bib82","year":"2011","issue":null,"author":"Stosovic","volume":"26","first-page":"607","unstructured":null,"article-title":"Could the level of serum albumin be a method for assessing malnutrition in hemodialysis patients?","journal-title":"Nut in Clin Prac","doi-asserted-by":"publisher"},{"DOI":"10.2215/CJN.10251011","key":"2026050510414863300_bib83","year":"2012","issue":null,"author":"Gama-Axelsson","volume":"7","first-page":"1446","unstructured":null,"article-title":"Serum albumin as predictor of nutritional status in patients with ESRD","journal-title":"Clin J Am Soc Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1136/bmjopen-2017-020023","key":"2026050510414863300_bib84","year":"2018","issue":null,"author":"Stevenson","volume":"8","first-page":"e020023","unstructured":null,"article-title":"Perspectives of healthcare providers on the nutritional management of patients on haemodialysis in Australia: an interview study","journal-title":"BMJ Open","doi-asserted-by":"publisher"},{"DOI":"10.2215/CJN.07800621","key":"2026050510414863300_bib85","year":"2022","issue":null,"author":"Wang","volume":"17","first-page":"38","unstructured":null,"article-title":"Assessing global kidney nutrition care","journal-title":"Clin J Am Soc Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.kint.2024.02.026","key":"2026050510414863300_bib86","year":"2024","issue":null,"author":"Chan","volume":"106","first-page":"35","unstructured":null,"article-title":"Frailty in patients on dialysis","journal-title":"Kidney Int","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu17061043","key":"2026050510414863300_bib87","year":"2025","issue":null,"author":"Czaja-Stolc","volume":"17","first-page":"1043","unstructured":null,"article-title":"Nutritional status, uremic toxins, and metabo-inflammatory biomarkers as predictors of two-year cardiovascular mortality in dialysis patients: a prospective study","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1371/journal.pone.0317510","key":"2026050510414863300_bib88","year":"2025","issue":null,"author":"Aydın Güçlü","volume":"20","first-page":"e0317510","unstructured":null,"article-title":"Impact of nutritional status and pulmonary function on short- and long-term overall survival in hemodialysis patients","journal-title":"PLoS One","doi-asserted-by":"crossref"},{"DOI":"10.1053/j.jrn.2020.09.003","key":"2026050510414863300_bib89","year":"2020","issue":null,"author":"Kalantar-Zadeh","volume":"30","first-page":"471","unstructured":null,"article-title":"Renal telenutrition for kidney health: leveraging telehealth and telemedicine for nutritional assessment and dietary management of patients with kidney disorders","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1080/0886022X.2025.2482885","key":"2026050510414863300_bib90","year":"2025","issue":null,"author":"Zhang","volume":"47","first-page":"2482885","unstructured":null,"article-title":"Enhancing treatment adherence in dialysis patients through digital health interventions: a systematic review and meta-analysis of randomized controlled trials","journal-title":"Ren Fail","doi-asserted-by":"publisher"},{"DOI":"10.2196/13808","key":"2026050510414863300_bib91","year":"2020","issue":null,"author":"Lim","volume":"8","first-page":"e13808","unstructured":null,"article-title":"Limitations of existing dialysis diet apps in promoting user engagement and patient self-management: quantitative content analysis study","journal-title":"JMIR Mhealth Uhealth","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2009.08.003","key":"2026050510414863300_bib92","year":"2010","issue":null,"author":"Sigrist","volume":"20","first-page":"1","unstructured":null,"article-title":"Systematic review of evidence for the use of intradialytic parenteral nutrition in malnourished hemodialysis patients","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2018.11.009","key":"2026050510414863300_bib93","year":"2019","issue":null,"author":"Anderson","volume":"29","first-page":"361","unstructured":null,"article-title":"Effectiveness of intradialytic parenteral nutrition in treating protein-energy wasting in hemodialysis: a rapid systematic review","journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":null,"key":"2026050510414863300_bib94","year":"2020","issue":null,"author":"Mah","volume":"5","first-page":"CD012616","unstructured":null,"article-title":"Oral protein-based supplements versus placebo or no treatment for people with chronic kidney disease requiring dialysis","journal-title":"Cochrane Database Syst Rev","doi-asserted-by":null},{"DOI":"10.3390/nu16050615","key":"2026050510414863300_bib95","year":"2024","issue":null,"author":"Marini","volume":"16","first-page":"615","unstructured":null,"article-title":"Effect of creatine supplementation on body composition and malnutrition-inflammation score in hemodialysis patients: an exploratory 1-year, balanced, double-blind design","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.mehy.2016.12.002","key":"2026050510414863300_bib96","year":"2017","issue":null,"author":"Wallimann","volume":"99","first-page":"1","unstructured":null,"article-title":"Intradialytic creatine supplementation: a scientific rationale for improving the health and quality of life of dialysis patients","journal-title":"Med Hypotheses","doi-asserted-by":"publisher"},{"DOI":"10.1681/ASN.0000000873","key":"2026050510414863300_bib97","year":"2025","issue":null,"author":"Biruete","volume":"36","first-page":"2244","unstructured":null,"article-title":"ASN kidney health guidance on potassium and phosphorus food additives","journal-title":"J Am Soc Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.mayocp.2019.05.019","key":"2026050510414863300_bib98","year":"2020","issue":null,"author":"Palmer","volume":"95","first-page":"339","unstructured":null,"article-title":"Potassium binders for hyperkalemia in chronic kidney disease—diet, renin–angiotensin–aldosterone system inhibitor therapy, and hemodialysis","journal-title":"Mayo Clin Proc","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu17040652","key":"2026050510414863300_bib99","year":"2025","issue":null,"author":"Climent","volume":"17","first-page":"652","unstructured":null,"article-title":"Psychobiotic protection of nutritional supplements and probiotics in patients undergoing hemodialysis: a randomized trial","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.3389/fmed.2025.1620247","key":"2026050510414863300_bib100","year":"2025","issue":null,"author":"Wang","volume":"12","first-page":"1620247","unstructured":null,"article-title":"Gut microbiome remodeling in chronic kidney disease: implications of kidney replacement therapies and therapeutic interventions","journal-title":"Front Med","doi-asserted-by":"publisher"},{"DOI":"10.3390/jcm10194456","key":"2026050510414863300_bib101","year":"2021","issue":null,"author":"Nguyen","volume":"10","first-page":"4456","unstructured":null,"article-title":"Effects of probiotics, prebiotics, and synbiotics on uremic toxins, inflammation, and oxidative stress in hemodialysis patients: a systematic review and meta-analysis of randomized controlled trials","journal-title":"J Clin Med","doi-asserted-by":"publisher"},{"DOI":"10.1056/nejmoa2513032","key":"2026050510414863300_bib102","year":"2026","issue":null,"author":"Lok","volume":"394","first-page":"128","unstructured":null,"article-title":"Fish-oil supplementation and cardiovascular events in patients receiving hemodialysis","journal-title":"N Engl J Med","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.ajkd.2021.06.005","key":"2026050510414863300_bib103","year":"2021","issue":null,"author":"Pourafshar","volume":"78","first-page":"624","unstructured":null,"article-title":"Reconsidering plant-based diets in patients receiving maintenance hemodialysis","journal-title":"Am J Kidney Dis","doi-asserted-by":"publisher"},{"DOI":"10.3390/jcm12196137","key":"2026050510414863300_bib104","year":"2023","issue":null,"author":"Zarantonello","volume":"12","first-page":"6137","unstructured":null,"article-title":"The role of plant-based diets in preventing and mitigating chronic kidney disease: more light than shadows","journal-title":"J Clin Med","doi-asserted-by":"publisher"},{"DOI":"10.1093/cdn/nzaa040_025","key":"2026050510414863300_bib105","year":"2020","issue":null,"author":"Garcia-Torres","volume":"4","first-page":"nzaa040_025","unstructured":null,"article-title":"Do plant-based diets provide adequate calories and protein for hemodialysis patients?","journal-title":"Curr Dev Nutr","doi-asserted-by":"publisher"},{"DOI":"10.3389/fnut.2023.1219976","key":"2026050510414863300_bib106","year":"2023","issue":null,"author":"Darzi","volume":"10","first-page":"1219976","unstructured":null,"article-title":"The association between plant and animal protein intake and quality of life in patients undergoing hemodialysis","journal-title":"Front Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.clnu.2023.01.018","key":"2026050510414863300_bib107","year":"2023","issue":null,"author":"Piccoli","volume":"42","first-page":"443","unstructured":null,"article-title":"Nutritional status and the risk of malnutrition in older adults with chronic kidney disease—implications for low protein intake and nutritional care: a critical review endorsed by ERN-ERA and ESPEN","journal-title":"Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu15245036","key":"2026050510414863300_bib108","year":"2023","issue":null,"author":"Ruperto","volume":"15","first-page":"5036","unstructured":null,"article-title":"Clinical significance of nutritional status, inflammation, and body composition in elderly hemodialysis patients-a case-control study","journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1093/ndt/gfw201","key":"2026050510414863300_bib109","year":"2017","issue":null,"author":"Johansson","volume":"32","first-page":"1127","unstructured":null,"article-title":"As we grow old: nutritional considerations for older patients on dialysis","journal-title":"Nephrol Dial Transplant","doi-asserted-by":"publisher"},{"DOI":"10.2215/CJN.0000000786","key":"2026050510414863300_bib110","year":"2025","issue":null,"author":"Mak","volume":null,"first-page":null,"unstructured":null,"article-title":"Nutrition across the entire lifespan in CKD: from childhood to senescence","journal-title":"Clin J Am Soc Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1186/s12882-024-03856-9","key":"2026050510414863300_bib111","year":"2024","issue":null,"author":"Patel","volume":"25","first-page":"464","unstructured":null,"article-title":"Modern tools for optimizing fluid management in dialysis patients: a comprehensive review","journal-title":"BMC Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.3390/medicina61091633","key":"2026050510414863300_bib112","year":"2025","issue":null,"author":"Jiménez Mayor","volume":"61","first-page":"1633","unstructured":null,"article-title":"Nutritional ultrasound in the morphofunctional assessment of malnutrition in patients undergoing incremental versus conventional hemodialysis: a comparative study","journal-title":"Medicina (Mex)","doi-asserted-by":"publisher"}],"short-title":[],"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5,1]]}},"article-number":"sfag117","content-domain":{"domain":[],"crossmark-restriction":false},"original-title":[],"container-title":["Clinical Kidney Journal"],"published-other":{"date-parts":[[2026,5]]},"published-print":{"date-parts":[[2026,5,1]]},"reference-count":112,"published-online":{"date-time":null,"timestamp":null,"date-parts":[[2026,4,16]]},"references-count":112,"short-container-title":[],"is-referenced-by-count":0},"unpaywall":{"doi":"10.1093/ckj/sfag117","is_oa":true,"title":"Personalized nutrition in haemodialysis: a scoping review of studies published between 2015 and 2025","updated":"2026-05-08T16:02:47+00:00","published_date":"2026-04-15","best_oa_location":{"url":"https://academic.oup.com/ckj/advance-article-pdf/doi/10.1093/ckj/sfag117/68093728/sfag117.pdf","pmh_id":null,"url_for_pdf":"https://academic.oup.com/ckj/advance-article-pdf/doi/10.1093/ckj/sfag117/68093728/sfag117.pdf","url_for_landing_page":"https://doi.org/10.1093/ckj/sfag117"}}},"created_at":"2026-05-07T22:50:38.010Z","updated_at":"2026-05-14T15:13:26.918Z","tags":[{"paper_doi":"10.1093/ckj/sfag117","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"age_group","value":"older_adult","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"category","value":"Urology & Nephrology","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"condition","value":"Chronic Kidney Disease","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"condition","value":"End-Stage Renal Disease","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"condition","value":"Protein-Energy Wasting","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"condition","value":"Sarcopenia","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"impact_flag","value":"limited_evidence","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"level_of_evidence","value":"5","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"modality","value":"Creatine Supplementation","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"modality","value":"Intradialytic Parenteral Nutrition","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"modality","value":"Omega-3 Fatty Acid Supplementation","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"modality","value":"Oral Nutritional Supplementation","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"modality","value":"Plant-Based Diet","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"modality","value":"Probiotic / Prebiotic / Synbiotic","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"sample_size","value":"n=30 studies","value_numeric":30},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"sex","value":"mixed","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"study_design","value":"Scoping Review","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"warning","value":"Sample size tag reflects number of included studies (n=30), not individual patients — total patient numbers vary widely across studies and are not reported in aggregate.","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"warning","value":"Several included studies are themselves systematic reviews or meta-analyses; the evidence hierarchy is therefore indirect for some conclusions.","value_numeric":null},{"paper_doi":"10.1093/ckj/sfag117","tag_type":"warning","value":"The scoping review design maps evidence but does not provide pooled effect estimates; impact flag 'limited_evidence' reflects the overall body of evidence reviewed, not a single trial.","value_numeric":null}],"summaries":{"what_studied":"A scoping review (JBI methodology, PRISMA-ScR) mapping evidence from 30 studies published January 2015–August 2025 on personalized nutritional strategies, barriers to care, and assessment tools in adult patients (≥18 years) undergoing maintenance haemodialysis (HD).","key_result":"Across 30 included studies (17 primary research, 13 reviews), dietary non-adherence affected ~60% of HD patients. Personalized oral/intradialytic supplementation, plant-forward diets, gut microbiota strategies, and targeted nutrients improved nutritional biomarkers and selected functional outcomes, but evidence was limited by small trials (<100 participants, 6–16 week follow-up) and high heterogeneity. Morphofunctional tools (muscle ultrasound, multifrequency BIA, MIS) outperformed serum albumin and BMI for detecting nutritional risk, especially in older adults. Only 36% of HD centres employed permanent renal dietitians, and <25% had standardized nutritional assessment protocols.","limitations":"- Most interventional studies were small and short-term, limiting generalizability and preventing firm recommendations.\n- Restriction to four databases and English-language publications may have missed relevant evidence.\n- Substantial methodological heterogeneity precluded meta-analysis; hard clinical endpoints (mortality, hospitalization) were rarely reported.","practice_takeaway":"Integrate renal dietitians and morphofunctional assessment (muscle ultrasound, BIA, MIS) into routine HD care rather than relying on albumin or BMI alone. Shift from rigid universal renal diets toward flexible, culturally adapted, patient-centred nutritional plans with structured psychosocial support to address the ~60% non-adherence rate."}},{"doi":"10.1186/s12882-025-04729-5","pmid":"41526893","title":"Plant-based low-protein diet for preventing malnutrition‒inflammation complex syndrome in adults with CKD: a single-centre preliminary experience","journal_title":"BMC Nephrology","journal_issn":"1471-2369","published_at":"2026-01-13T00:00:00.000Z","url":"https://doi.org/10.1186/s12882-025-04729-5","source_score":10,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2026-01-15","doi":"10.1186/s12882-025-04729-5","days":"7","issn":"1471-2369","rank":"7","field":"Clinical Medicine","score":"10","category":"Urology & Nephrology","categories":["Urology & Nephrology"],"_categories":["Urology & Nephrology"]},"pubmed":{"doi":"10.1186/s12882-025-04729-5","title":"Plant-based low-protein diet for preventing malnutrition‒inflammation complex syndrome in adults with CKD: a single-centre preliminary experience.","journal":"BMC nephrology","methods":"","results":"","abstract":"","keywords":["Chronic kidney disease","Low-protein diet","MICS","Malnutrition","PEW","Plant-based diet"],"pubmed_id":"41526893","conclusions":"","publication_date":"2026-01-13T00:00:00"},"crossref":{"DOI":"10.1186/s12882-025-04729-5","URL":"https://doi.org/10.1186/s12882-025-04729-5","ISSN":["1471-2369"],"link":[{"URL":"https://link.springer.com/article/10.1186/s12882-025-04729-5","content-type":"text/html","content-version":"vor","intended-application":"text-mining"}],"page":null,"type":"journal-article","issue":null,"score":1,"title":["Plant-based low-protein diet for preventing malnutrition‒inflammation complex syndrome in adults with CKD: a single-centre preliminary experience"],"author":[{"given":"Maria","family":"Amicone","sequence":"first","affiliation":[]},{"given":"Mariastella","family":"Di Lauro","sequence":"additional","affiliation":[]},{"given":"Manuela","family":"Rizzo","sequence":"additional","affiliation":[]},{"given":"Tonia","family":"Di Lorenzo","sequence":"additional","affiliation":[]},{"given":"Giuseppe","family":"Gigliotti","sequence":"additional","affiliation":[]},{"given":"Antonio","family":"Pisani","sequence":"additional","affiliation":[]},{"given":"Ivana","family":"Capuano","sequence":"additional","affiliation":[]},{"given":"Nunzia","family":"Cacciapuoti","sequence":"additional","affiliation":[]},{"given":"Bruna","family":"Guida","sequence":"additional","affiliation":[]},{"given":"Maria Serena","family":"Lonardo","sequence":"additional","affiliation":[]}],"issued":{"date-parts":[[2026,1,12]]},"member":"297","prefix":"10.1186","source":"Crossref","volume":null,"created":{"date-time":"2026-01-12T09:04:21Z","timestamp":1768208661000,"date-parts":[[2026,1,12]]},"indexed":{"date-time":"2026-01-12T12:05:19Z","timestamp":1768219519540,"date-parts":[[2026,1,12]]},"license":[{"URL":"https://creativecommons.org/licenses/by-nc-nd/4.0","start":{"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000,"date-parts":[[2026,1,12]]},"delay-in-days":0,"content-version":"tdm"},{"URL":"https://creativecommons.org/licenses/by-nc-nd/4.0","start":{"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000,"date-parts":[[2026,1,12]]},"delay-in-days":0,"content-version":"am"}],"subject":[],"abstract":null,"language":"en","relation":{},"resource":{"primary":{"URL":"https://link.springer.com/10.1186/s12882-025-04729-5"}},"subtitle":[],"assertion":[{"name":"received","group":{"name":"ArticleHistory","label":"Article History"},"label":"Received","order":1,"value":"23 July 2025"},{"name":"accepted","group":{"name":"ArticleHistory","label":"Article History"},"label":"Accepted","order":2,"value":"29 December 2025"},{"name":"first_online","group":{"name":"ArticleHistory","label":"Article History"},"label":"First Online","order":3,"value":"12 January 2026"},{"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"},"order":1},{"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"},"order":2,"value":"This study was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki, and it was approved by approved by the Institutional Ethical Committee of the Federico II University Medical School of Naples as part of a previous data-banking project (Project identification code 181/18, approval date 18 July 2018). All patients provided written inform consent for the study."},{"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"},"order":3,"value":"Not applicable."},{"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"},"order":4,"value":"The authors declare no competing interests."}],"deposited":{"date-time":"2026-01-12T09:04:24Z","timestamp":1768208664000,"date-parts":[[2026,1,12]]},"issn-type":[{"type":"electronic","value":"1471-2369"}],"published":{"date-parts":[[2026,1,12]]},"publisher":"Springer Science and Business Media LLC","reference":[{"DOI":"10.3389/fpubh.2024.1436236","key":"4729_CR1","year":"2024","issue":null,"author":"M Taheri Soodejani","volume":"12","first-page":"1436236","unstructured":"Taheri Soodejani M. Noncommunicable diseases in the world over the past century: a secondary data analysis. Front Public Health. 2024;12:1436236. https://doi.org/10.3389/fpubh.2024.1436236.","article-title":null,"journal-title":"Front Public Health","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.kint.2023.10.018","key":"4729_CR2","year":"2024","issue":"4","author":"PE Stevens","volume":"105","first-page":"S117","unstructured":"Stevens PE, Ahmed SB, Carrero JJ, et al. KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int. 2024;105(4):S117–314. https://doi.org/10.1016/j.kint.2023.10.018.","article-title":null,"journal-title":"Kidney Int","doi-asserted-by":"publisher"},{"DOI":"10.3390/genes14061236","key":"4729_CR3","year":"2023","issue":"6","author":"E Nigro","volume":"14","first-page":"1236","unstructured":"Nigro E, Amicone M, D’Arco D, et al. Molecular diagnosis and identification of novel pathogenic variants in a large cohort of Italian patients affected by polycystic kidney diseases. Genes. 2023;14(6):1236. https://doi.org/10.3390/genes14061236.","article-title":null,"journal-title":"Genes","doi-asserted-by":"publisher"},{"DOI":"10.1038/s41581-024-00820-6","key":"4729_CR4","year":"2024","issue":"7","author":"A Francis","volume":"20","first-page":"473","unstructured":"Francis A, Harhay MN, Ong ACM, et al. Chronic kidney disease and the global public health agenda: an international consensus. Nat Rev Nephrol. 2024;20(7):473–85. https://doi.org/10.1038/s41581-024-00820-6.","article-title":null,"journal-title":"Nat Rev Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.ajkd.2023.09.020","key":"4729_CR5","year":"2024","issue":"5","author":"S Amir","volume":"83","first-page":"624","unstructured":"Amir S, Kim H, Hu EA, et al. Adherence to Plant-Based diets and risk of CKD progression and All-Cause mortality: findings from the chronic renal insufficiency cohort (CRIC) study. Am J Kidney Dis. 2024;83(5):624–35. https://doi.org/10.1053/j.ajkd.2023.09.020.","article-title":null,"journal-title":"Am J Kidney Dis","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu16071061","key":"4729_CR6","year":"2024","issue":"7","author":"G Muscogiuri","volume":"16","first-page":"1061","unstructured":"Muscogiuri G, De Marco O, Di Lorenzo T, et al. Diet and physical activity in Fabry disease: A narrative review. Nutrients. 2024;16(7):1061. https://doi.org/10.3390/nu16071061.","article-title":null,"journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.3390/jcm9113644","key":"4729_CR7","year":"2020","issue":"11","author":"A Cupisti","volume":"9","first-page":"3644","unstructured":"Cupisti A, Gallieni M, Avesani CM, D’Alessandro C, Carrero JJ, Piccoli GB. Medical nutritional therapy for patients with chronic kidney disease not on dialysis: the low protein diet as a medication. J Clin Med. 2020;9(11):3644. https://doi.org/10.3390/jcm9113644.","article-title":null,"journal-title":"J Clin Med","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.ajkd.2020.05.006","key":"4729_CR8","year":"2020","issue":"3","author":"TA Ikizler","volume":"76","first-page":"S1","unstructured":"Ikizler TA, Burrowes JD, Byham-Gray LD, et al. KDOQI clinical practice guideline for nutrition in CKD: 2020 update. Am J Kidney Dis. 2020;76(3):S1–107. https://doi.org/10.1053/j.ajkd.2020.05.006.","article-title":null,"journal-title":"Am J Kidney Dis","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.ajkd.2004.08.020","key":"4729_CR9","year":"2004","issue":"6","author":"AN Friedman","volume":"44","first-page":"950","unstructured":"Friedman AN. High-protein diets: potential effects on the kidney in renal health and disease. Am J Kidney Dis. 2004;44(6):950–62. https://doi.org/10.1053/j.ajkd.2004.08.020.","article-title":null,"journal-title":"Am J Kidney Dis","doi-asserted-by":"publisher"},{"DOI":"10.1159/000504240","key":"4729_CR10","year":"2020","issue":"1–2","author":"RM Hanna","volume":"49","first-page":"202","unstructured":"Hanna RM, Ghobry L, Wassef O, Rhee CM, Kalantar-Zadeh K. A practical approach to Nutrition, Protein-Energy Wasting, Sarcopenia, and cachexia in patients with chronic kidney disease. Blood Purif. 2020;49(1–2):202–11. https://doi.org/10.1159/000504240.","article-title":null,"journal-title":"Blood Purif","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.numecd.2023.06.015","key":"4729_CR11","year":"2023","issue":"11","author":"MS Lonardo","volume":"33","first-page":"2169","unstructured":"Lonardo MS, Cacciapuoti N, Chiurazzi M, et al. Combined use of handgrip strength and hemoglobin as markers of undernutrition in patients with stage 3–5 chronic kidney disease. Nutr Metab Cardiovasc Dis. 2023;33(11):2169–78. https://doi.org/10.1016/j.numecd.2023.06.015.","article-title":null,"journal-title":"Nutr Metab Cardiovasc Dis","doi-asserted-by":"publisher"},{"DOI":"10.3389/fped.2018.00161","key":"4729_CR12","year":"2018","issue":null,"author":"FM Iorember","volume":"6","first-page":"161","unstructured":"Iorember FM. Malnutrition in chronic kidney disease. Front Pediatr. 2018;6:161. https://doi.org/10.3389/fped.2018.00161.","article-title":null,"journal-title":"Front Pediatr","doi-asserted-by":"publisher"},{"DOI":"10.7860/JCDR/2013/5329.2907","key":"4729_CR13","year":"2013","issue":null,"author":"N Anand","volume":null,"first-page":null,"unstructured":"Anand N. The malnutrition inflammation complex Syndrome-The micsing factor in the Perio-Chronic kidney disease interlink. J Clin Diagn Res Published Online. 2013. https://doi.org/10.7860/JCDR/2013/5329.2907.","article-title":null,"journal-title":"J Clin Diagn Res Published Online","doi-asserted-by":"publisher"},{"DOI":"10.3390/antiox9080752","key":"4729_CR14","year":"2020","issue":"8","author":"A Podkowińska","volume":"9","first-page":"752","unstructured":"Podkowińska A, Formanowicz D. Chronic kidney disease as oxidative Stress- and Inflammatory-Mediated cardiovascular disease. Antioxidants. 2020;9(8):752. https://doi.org/10.3390/antiox9080752.","article-title":null,"journal-title":"Antioxidants","doi-asserted-by":"publisher"},{"DOI":"10.1159/000137684","key":"4729_CR15","year":"2008","issue":"5","author":"LC Ho","volume":"28","first-page":"840","unstructured":"Ho LC, Wang HH, Peng YS, et al. Clinical utility of malnutrition-inflammation score in maintenance Hemodialysis patients: focus on identifying the best cut-off point. Am J Nephrol. 2008;28(5):840–6. https://doi.org/10.1159/000137684.","article-title":null,"journal-title":"Am J Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.6133/apjcn.2016.25.1.01","key":"4729_CR16","year":"2016","issue":"1","author":"GS Harvinder","volume":"25","first-page":"26","unstructured":"Harvinder GS, Swee WC, Karupaiah T, et al. Dialysis malnutrition and malnutrition inflammation scores: screening tools for prediction of dialysis-related protein-energy wasting in Malaysia. Asia Pac J Clin Nutr. 2016;25(1):26–33. https://doi.org/10.6133/apjcn.2016.25.1.01.","article-title":null,"journal-title":"Asia Pac J Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1186/s12882-023-03233-y","key":"4729_CR17","year":"2023","issue":"1","author":"Ł Świątek","volume":"24","first-page":"168","unstructured":"Świątek Ł, Jeske J, Miedziaszczyk M, Idasiak-Piechocka I. The impact of a vegetarian diet on chronic kidney disease (CKD) progression – a systematic review. BMC Nephrol. 2023;24(1):168. https://doi.org/10.1186/s12882-023-03233-y.","article-title":null,"journal-title":"BMC Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.7326/0003-4819-150-9-200905050-00006","key":"4729_CR18","year":"2009","issue":"9","author":"AS Levey","volume":"150","first-page":"604","unstructured":"Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604. https://doi.org/10.7326/0003-4819-150-9-200905050-00006.","article-title":null,"journal-title":"Ann Intern Med","doi-asserted-by":"publisher"},{"DOI":"10.1093/ajcn/64.3.524S","key":"4729_CR19","year":"1996","issue":"3","author":"National Institutes of Health Technology Assessment Conference Statement","volume":"64","first-page":"S524","unstructured":"National Institutes of Health Technology Assessment Conference Statement. Bioelectrical impedance analysis in body composition measurement. Am J Clin Nutr. 1996;64(3):S524–32. https://doi.org/10.1093/ajcn/64.3.524S.","article-title":null,"journal-title":"Am J Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1080/07315724.1992.12098245","key":"4729_CR20","year":"1992","issue":"2","author":"RF Kushner","volume":"11","first-page":"199","unstructured":"Kushner RF. Bioelectrical impedance analysis: a review of principles and applications. J Am Coll Nutr. 1992;11(2):199–209.","article-title":null,"journal-title":"J Am Coll Nutr","doi-asserted-by":"crossref"},{"DOI":"10.1016/j.clnu.2018.05.024","key":"4729_CR21","year":"2019","issue":"1","author":"D Volkert","volume":"38","first-page":"10","unstructured":"Volkert D, Beck AM, Cederholm T, et al. ESPEN guideline on clinical nutrition and hydration in geriatrics. Clin Nutr. 2019;38(1):10–47. https://doi.org/10.1016/j.clnu.2018.05.024.","article-title":null,"journal-title":"Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1152/jappl.2000.89.2.465","key":"4729_CR22","year":"2000","issue":"2","author":"I Janssen","volume":"89","first-page":"465","unstructured":"Janssen I, Heymsfield SB, Baumgartner RN, Ross R. Estimation of skeletal muscle mass by bioelectrical impedance analysis. J Appl Physiol. 2000;89(2):465–71. https://doi.org/10.1152/jappl.2000.89.2.465.","article-title":null,"journal-title":"J Appl Physiol","doi-asserted-by":"publisher"},{"DOI":"10.1016/S0261-5614(03)00048-7","key":"4729_CR23","year":"2003","issue":"6","author":"UG Kyle","volume":"22","first-page":"537","unstructured":"Kyle UG, Genton L, Hans D, Pichard C. Validation of a bioelectrical impedance analysis equation to predict appendicular skeletal muscle mass (ASMM). Clin Nutr. 2003;22(6):537–43. https://doi.org/10.1016/S0261-5614(03)00048-7.","article-title":null,"journal-title":"Clin Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1053/ajkd.2001.29222","key":"4729_CR24","year":"2001","issue":"6","author":"K Kalantar-Zadeh","volume":"38","first-page":"1251","unstructured":"Kalantar-Zadeh K, Kopple JD, Block G, Humphreys MH. A Malnutrition-Inflammation score is correlated with morbidity and mortality in maintenance Hemodialysis patients. Am J Kidney Dis. 2001;38(6):1251–63. https://doi.org/10.1053/ajkd.2001.29222.","article-title":null,"journal-title":"Am J Kidney Dis","doi-asserted-by":"publisher"},{"DOI":"10.1093/ndt/gfu380","key":"4729_CR25","year":"2015","issue":"5","author":"FC Amparo","volume":"30","first-page":"821","unstructured":"Amparo FC, Kamimura MA, Molnar MZ, et al. Diagnostic validation and prognostic significance of the Malnutrition-Inflammation score in nondialyzed chronic kidney disease patients. Nephrol Dial Transpl. 2015;30(5):821–8. https://doi.org/10.1093/ndt/gfu380.","article-title":null,"journal-title":"Nephrol Dial Transpl","doi-asserted-by":"publisher"},{"DOI":"10.1007/s11255-015-0984-2","key":"4729_CR26","year":"2015","issue":"6","author":"MZ Molnar","volume":"47","first-page":"1025","unstructured":"Molnar MZ, Carrero JJ, Mucsi I, et al. Comparison of the malnutrition–inflammation score in chronic kidney disease patients and kidney transplant recipients. Int Urol Nephrol. 2015;47(6):1025–33. https://doi.org/10.1007/s11255-015-0984-2.","article-title":null,"journal-title":"Int Urol Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1177/089686080602600616","key":"4729_CR27","year":"2006","issue":"6","author":"B Afşar","volume":"26","first-page":"705","unstructured":"Afşar B, Sezer S, Ozdemir FN, Celik H, Elsurer R, Haberal M. Malnutrition-inflammation score is a useful tool in peritoneal Dialysis patients. Perit Dial Int J Int Soc Perit Dial. 2006;26(6):705–11.","article-title":null,"journal-title":"Perit Dial Int J Int Soc Perit Dial","doi-asserted-by":"crossref"},{"DOI":"10.5414/CN107659","key":"4729_CR28","year":"2013","issue":"06","author":"T He","volume":"79","first-page":"477","unstructured":"He T, An X, Mao HP, et al. Malnutrition-inflammation score predicts long-term mortality in Chinese PD patients. Clin Nephrol. 2013;79(06):477–83. https://doi.org/10.5414/CN107659.","article-title":null,"journal-title":"Clin Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1093/ageing/afz046","key":"4729_CR29","year":"2019","issue":"4","author":"AJ Cruz-Jentoft","volume":"48","first-page":"601","unstructured":"Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(4):601–601. https://doi.org/10.1093/ageing/afz046.","article-title":null,"journal-title":"Age Ageing","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2010.05.013","key":"4729_CR30","year":"2011","issue":"3","author":"K Kalantar-Zadeh","volume":"21","first-page":"257","unstructured":"Kalantar-Zadeh K, Kovesdy CP, Bross R, et al. Design and development of a Dialysis food frequency questionnaire. J Ren Nutr. 2011;21(3):257–62. https://doi.org/10.1053/j.jrn.2010.05.013.","article-title":null,"journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":null,"key":"4729_CR31","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":"CREA. 2019. Linee guida per un asana alimentazione-Revisione 2018. https://www.crea.gov.it/web/alimenti-e-nutrizione/-/linee-guida-per-una-sana-alimentazione-2018.","article-title":null,"journal-title":null,"doi-asserted-by":null},{"DOI":"10.1053/j.ajkd.2018.11.010","key":"4729_CR32","year":"2019","issue":"6","author":"A Bajaj","volume":"73","first-page":"827","unstructured":"Bajaj A, Xie D, Cedillo-Couvert E, et al. Lipids, Apolipoproteins, and risk of atherosclerotic cardiovascular disease in persons with CKD. Am J Kidney Dis. 2019;73(6):827–36. https://doi.org/10.1053/j.ajkd.2018.11.010.","article-title":null,"journal-title":"Am J Kidney Dis","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.jada.2009.12.006","key":"4729_CR33","year":"2010","issue":"2","author":"P Kris-Etherton","volume":"110","first-page":"201","unstructured":"Kris-Etherton P, Fleming J, Harris WS. The debate about n-6 polyunsaturated fatty acid recommendations for cardiovascular health. J Am Diet Assoc. 2010;110(2):201–4. https://doi.org/10.1016/j.jada.2009.12.006.","article-title":null,"journal-title":"J Am Diet Assoc","doi-asserted-by":"publisher"},{"DOI":"10.3390/ijms21020601","key":"4729_CR34","year":"2020","issue":"2","author":"J Rysz","volume":"21","first-page":"601","unstructured":"Rysz J, Gluba-Brzózka A, Rysz-Górzyńska M, Franczyk B. The role and function of HDL in patients with chronic kidney disease and the risk of cardiovascular disease. Int J Mol Sci. 2020;21(2):601. https://doi.org/10.3390/ijms21020601.","article-title":null,"journal-title":"Int J Mol Sci","doi-asserted-by":"publisher"},{"DOI":"10.2174/0929867328666210714155422","key":"4729_CR35","year":"2022","issue":"10","author":"CE Kosmas","volume":"29","first-page":"1687","unstructured":"Kosmas CE, Sourlas A, Guzman E, Kostara CE. Environmental factors modifying HDL functionality. Curr Med Chem. 2022;29(10):1687–701. https://doi.org/10.2174/0929867328666210714155422.","article-title":null,"journal-title":"Curr Med Chem","doi-asserted-by":"publisher"},{"DOI":"10.1007/s40279-020-01364-y","key":"4729_CR36","year":"2021","issue":"2","author":"A Palazón-Bru","volume":"51","first-page":"243","unstructured":"Palazón-Bru A, Hernández-Lozano D, Gil-Guillén VF. Which physical exercise interventions increase HDL-Cholesterol levels? A systematic review of Meta-analyses of randomized controlled trials. Sports Med. 2021;51(2):243–53. https://doi.org/10.1007/s40279-020-01364-y.","article-title":null,"journal-title":"Sports Med","doi-asserted-by":"publisher"},{"DOI":"10.1016/j.ihj.2023.11.270","key":"4729_CR37","year":"2024","issue":null,"author":"K Madan","volume":"76","first-page":"S73","unstructured":"Madan K, Sawhney JPS. Exercise and lipids. Indian Heart J. 2024;76:S73–4. https://doi.org/10.1016/j.ihj.2023.11.270.","article-title":null,"journal-title":"Indian Heart J","doi-asserted-by":"publisher"},{"DOI":"10.2215/CJN.03670807","key":"4729_CR38","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":"Stenvinkel P, Carrero JJAA, Axelsson J, Lindholm B, Heimbu[Combining Diaeresis]rger O, Massy Z. Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle? Clin J Am Soc Nephrol. 2008;3(2):505–521. https://doi.org/10.2215/CJN.03670807.","article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1053/j.ajkd.2003.10.037","key":"4729_CR39","year":"2004","issue":"2","author":"MJ Landray","volume":"43","first-page":"244","unstructured":"Landray MJ, Wheeler DC, Lip GYH, et al. Inflammation, endothelial dysfunction, and platelet activation in patients with chronic kidney disease: the chronic renal impairment in Birmingham (CRIB) study. Am J Kidney Dis. 2004;43(2):244–53. https://doi.org/10.1053/j.ajkd.2003.10.037.","article-title":null,"journal-title":"Am J Kidney Dis","doi-asserted-by":"publisher"},{"DOI":"10.3390/life11050419","key":"4729_CR40","year":"2021","issue":"5","author":"F Tinti","volume":"11","first-page":"419","unstructured":"Tinti F, Lai S, Noce A, et al. Chronic kidney disease as a systemic inflammatory syndrome: update on mechanisms involved and potential treatment. Life. 2021;11(5):419. https://doi.org/10.3390/life11050419.","article-title":null,"journal-title":"Life","doi-asserted-by":"publisher"},{"DOI":"10.1093/ndt/gfs132","key":"4729_CR41","year":"2012","issue":"9","author":"X Huang","volume":"27","first-page":"3615","unstructured":"Huang X, Stenvinkel P, Qureshi AR, et al. Essential polyunsaturated fatty acids, inflammation and mortality in Dialysis patients. Nephrol Dial Transpl. 2012;27(9):3615–20. https://doi.org/10.1093/ndt/gfs132.","article-title":null,"journal-title":"Nephrol Dial Transpl","doi-asserted-by":"publisher"},{"DOI":"10.1007/s40620-021-01194-9","key":"4729_CR42","year":"2022","issue":"1","author":"B Guida","volume":"35","first-page":"95","unstructured":"Guida B, Lonardo MS, Cataldi M. Flavonoids and ω3-polyunsaturated fatty acid supplementation in renal transplant recipients: new arguments from COVID-19. J Nephrol. 2022;35(1):95–7. https://doi.org/10.1007/s40620-021-01194-9.","article-title":null,"journal-title":"J Nephrol","doi-asserted-by":"publisher"},{"DOI":null,"key":"4729_CR43","year":"2007","issue":"12","author":"UN Das","volume":"13","first-page":"RA214","unstructured":"Das UN. Acetylcholinesterase and butyrylcholinesterase as possible markers of low-grade systemic inflammation. Med Sci Monit Int Med J Exp Clin Res. 2007;13(12):RA214–221.","article-title":null,"journal-title":"Med Sci Monit Int Med J Exp Clin Res","doi-asserted-by":null},{"DOI":"10.1007/s11255-023-03679-x","key":"4729_CR44","year":"2023","issue":"1","author":"W Wu","volume":"56","first-page":"335","unstructured":"Wu W, Li X, Di J, Zhou H, Niu H, Yang M. Dietary inflammatory index is associated with vitamin D in CKD patients. Int Urol Nephrol. 2023;56(1):335–44. https://doi.org/10.1007/s11255-023-03679-x.","article-title":null,"journal-title":"Int Urol Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1371/journal.pone.0118174","key":"4729_CR45","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":"Riccio E, Sabbatini M, Bruzzese D et al. Effect of paricalcitol vs calcitriol on hemoglobin levels in chronic kidney disease patients: a randomized trial. Cameron DW, ed. PLOS ONE. 2015;10(3):e0118174. https://doi.org/10.1371/journal.pone.0118174.","article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.nutres.2015.11.013","key":"4729_CR46","year":"2016","issue":"3","author":"PK Pannu","volume":"36","first-page":"201","unstructured":"Pannu PK, Zhao Y, Soares MJ. Reductions in body weight and percent fat mass increase the vitamin D status of obese subjects: a systematic review and metaregression analysis. Nutr Res. 2016;36(3):201–13. https://doi.org/10.1016/j.nutres.2015.11.013.","article-title":null,"journal-title":"Nutr Res","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu16050632","key":"4729_CR47","year":"2024","issue":"5","author":"N Cacciapuoti","volume":"16","first-page":"632","unstructured":"Cacciapuoti N, Lonardo MS, Di Lauro M, et al. Effects of dietary intervention on nutritional status in elderly individuals with chronic kidney disease. Nutrients. 2024;16(5):632. https://doi.org/10.3390/nu16050632.","article-title":null,"journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1681/ASN.2015040369","key":"4729_CR48","year":"2016","issue":"7","author":"L Garneata","volume":"27","first-page":"2164","unstructured":"Garneata L, Stancu A, Dragomir D, Stefan G, Mircescu G. Ketoanalogue-Supplemented vegetarian very Low–Protein diet and CKD progression. J Am Soc Nephrol. 2016;27(7):2164–76. https://doi.org/10.1681/ASN.2015040369.","article-title":null,"journal-title":"J Am Soc Nephrol","doi-asserted-by":"publisher"},{"DOI":"10.1177/15598276241291490","key":"4729_CR49","year":"2024","issue":null,"author":"S Musial","volume":"1","first-page":"155982762412914","unstructured":"Musial S, Burns Z, Bertman J, Fitzgibbon M, Mashek R, Risica PM. One month whole food Plant-Based nutrition educational program lowers LDL, A1C, and decreases inflammatory markers. Am J Lifestyle Med Published Online November. 2024;1:15598276241291490. https://doi.org/10.1177/15598276241291490.","article-title":null,"journal-title":"Am J Lifestyle Med Published Online November","doi-asserted-by":"publisher"},{"DOI":"10.3390/ijms151121505","key":"4729_CR50","year":"2014","issue":"11","author":"H Jung","volume":"15","first-page":"21505","unstructured":"Jung H, Lim Y, Kim EK. Therapeutic phytogenic compounds for obesity and diabetes. Int J Mol Sci. 2014;15(11):21505–37. https://doi.org/10.3390/ijms151121505.","article-title":null,"journal-title":"Int J Mol Sci","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu12071931","key":"4729_CR51","year":"2020","issue":"7","author":"K Kalantar-Zadeh","volume":"12","first-page":"1931","unstructured":"Kalantar-Zadeh K, Joshi S, Schlueter R, et al. Plant-Dominant Low-Protein diet for Conservative management of chronic kidney disease. Nutrients. 2020;12(7):1931. https://doi.org/10.3390/nu12071931.","article-title":null,"journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1093/ndt/gfaa232","key":"4729_CR52","year":"2021","issue":"11","author":"CI Ramos","volume":"36","first-page":"2049","unstructured":"Ramos CI, González-Ortiz A, Espinosa-Cuevas A, Avesani CM, Carrero JJ, Cuppari L. Does dietary potassium intake associate with hyperkalaemia in patients with chronic kidney disease? Nephrol Dial Transpl. 2021;36(11):2049–57. https://doi.org/10.1093/ndt/gfaa232.","article-title":null,"journal-title":"Nephrol Dial Transpl","doi-asserted-by":"publisher"},{"DOI":"10.3390/nu15112454","key":"4729_CR53","year":"2023","issue":"11","author":"D Giannese","volume":"15","first-page":"2454","unstructured":"Giannese D, D’Alessandro C, Pellegrino N, Panichi V, Cupisti A. RAASi therapy attenuates the association between 24-h urinary potassium excretion and dietary potassium intake in CKD patients. Nutrients. 2023;15(11):2454. https://doi.org/10.3390/nu15112454.","article-title":null,"journal-title":"Nutrients","doi-asserted-by":"publisher"},{"DOI":"10.1053/j.jrn.2024.03.008","key":"4729_CR54","year":"2024","issue":"6","author":"N Morimoto","volume":"34","first-page":"519","unstructured":"Morimoto N, Shioji S, Akagi Y, et al. Associations between dietary potassium intake from different food sources and hyperkalaemia in patients with chronic kidney disease. J Ren Nutr. 2024;34(6):519–29. https://doi.org/10.1053/j.jrn.2024.03.008.","article-title":null,"journal-title":"J Ren Nutr","doi-asserted-by":"publisher"},{"DOI":"10.1159/000371498","key":"4729_CR55","year":"2014","issue":"6","author":"RN Moorthi","volume":"40","first-page":"582","unstructured":"Moorthi RN, Armstrong CLH, Janda K, Ponsler-Sipes K, Asplin JR, Moe SM. The effect of a diet containing 70% protein from plants on mineral metabolism and musculoskeletal health in chronic kidney disease. Am J Nephrol. 2014;40(6):582–91. https://doi.org/10.1159/000371498.","article-title":null,"journal-title":"Am J Nephrol","doi-asserted-by":"publisher"}],"short-title":[],"update-policy":"https://doi.org/10.1007/springer_crossmark_policy","alternative-id":["4729"],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"original-title":[],"container-title":["BMC Nephrology"],"reference-count":55,"published-online":{"date-time":null,"timestamp":null,"date-parts":[[2026,1,12]]},"references-count":55,"short-container-title":["BMC Nephrol"],"is-referenced-by-count":0},"unpaywall":{"doi":"10.1186/s12882-025-04729-5","is_oa":true,"title":"Plant-based low-protein diet for preventing malnutrition‒inflammation complex syndrome in adults with CKD: a single-centre preliminary experience","updated":"2026-01-13T16:36:47+00:00","published_date":"2026-01-12","best_oa_location":{"url":"https://doi.org/10.1186/s12882-025-04729-5","pmh_id":null,"url_for_pdf":null,"url_for_landing_page":"https://doi.org/10.1186/s12882-025-04729-5"}}},"created_at":"2026-01-21T12:05:26.220Z","updated_at":"2026-01-21T12:05:26.220Z","tags":[{"paper_doi":"10.1186/s12882-025-04729-5","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1186/s12882-025-04729-5","tag_type":"category","value":"Urology & Nephrology","value_numeric":null},{"paper_doi":"10.1186/s12882-025-04729-5","tag_type":"condition","value":"Chronic Kidney Disease","value_numeric":null},{"paper_doi":"10.1186/s12882-025-04729-5","tag_type":"condition","value":"Malnutrition-Inflammation Complex Syndrome","value_numeric":null},{"paper_doi":"10.1186/s12882-025-04729-5","tag_type":"modality","value":"Low-Protein Diet","value_numeric":null},{"paper_doi":"10.1186/s12882-025-04729-5","tag_type":"modality","value":"Plant-Based Diet","value_numeric":null},{"paper_doi":"10.1186/s12882-025-04729-5","tag_type":"study_design","value":"Case Series","value_numeric":null},{"paper_doi":"10.1186/s12882-025-04729-5","tag_type":"warning","value":"Only citation/title details were available; outcomes, sample size, and comparators were not provided.","value_numeric":null},{"paper_doi":"10.1186/s12882-025-04729-5","tag_type":"warning","value":"Study design classification is inferred from the title and may be inaccurate.","value_numeric":null}],"summaries":{"what_studied":"A single-centre preliminary experience evaluated a plant‑based low‑protein diet to prevent malnutrition–inflammation complex syndrome in adults with chronic kidney disease.","limitations":"Single‑centre and preliminary experience."}},{"doi":"10.1161/jaha.125.045515","pmid":"41220152","title":"Prevention and Reversal of Hypertension‐Induced Coronary Microvascular Dysfunction by a Plant‐Based Diet","journal_title":"Journal of the American Heart Association","journal_issn":"2047-9980","published_at":"2025-11-12T00:00:00.000Z","url":"https://doi.org/10.1161/jaha.125.045515","source_score":139,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2025-11-16","doi":"10.1161/jaha.125.045515","days":"30","issn":"2047-9980","rank":"7","field":"Clinical Medicine","score":"139","category":"Cardiac & Cardiovascular Systems","categories":["Cardiac & Cardiovascular Systems"],"_categories":["Cardiac & Cardiovascular Systems"]},"pubmed":{"doi":"10.1161/JAHA.125.045515","title":"Prevention and Reversal of Hypertension-Induced Coronary Microvascular Dysfunction by a Plant-Based Diet.","journal":"Journal of the American Heart Association","methods":"","results":"SHRs exhibited endothelial dysfunction and likely VSMC dysfunction. A PBD did not ameliorate their hypertension but, nonetheless, prevented and reversed CMD. The PBD's mitigation of CMD was associated with improved endothelial nitric oxide synthase function and nitric oxide-mediated VSMC signaling, as well as reductions in left ventricular oxidative stress, inflammatory signaling, and fibrosis. A PBD altered the gut microbiota, although antibiotic studies failed to establish its importance in ameliorating CMD.","abstract":"$32","keywords":["MRI","endothelial function","hypertension","microvascular dysfunction","nutrition","plant‐based diet"],"pubmed_id":"41220152","conclusions":"","publication_date":"2025-11-12T00:00:00"},"crossref":{"DOI":"10.1161/jaha.125.045515","URL":"https://doi.org/10.1161/jaha.125.045515","ISSN":["2047-9980"],"link":[{"URL":"https://www.ahajournals.org/doi/full/10.1161/JAHA.125.045515","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":null,"type":"journal-article","issue":"22","score":1,"title":["Prevention and Reversal of Hypertension‐Induced Coronary Microvascular Dysfunction by a Plant‐Based Diet"],"author":[{"given":"Rami S.","family":"Najjar","sequence":"first","affiliation":[{"name":"Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences"},{"name":"Georgia State University"},{"name":"Emory Clinical Cardiovascular Research Institute, Division of Cardiology"},{"name":"Emory University School of Medicine"}]},{"given":"Nedumangalam","family":"Hekmatyar","sequence":"additional","affiliation":[{"name":"Advanced Translational Imaging Facility"},{"name":"Georgia State University"}]},{"given":"Yanling","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences"},{"name":"Georgia State University"}]},{"given":"Vu","family":"Ngo","sequence":"additional","affiliation":[{"name":"Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences"},{"name":"Georgia State University"}]},{"given":"Hannah L.","family":"Lail","sequence":"additional","affiliation":[{"name":"Georgia State University"},{"name":"Georgia State University"}]},{"given":"Juan P.","family":"Tejada","sequence":"additional","affiliation":[{"name":"Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences"},{"name":"Georgia State University"}]},{"given":"Jessica P.","family":"Danh","sequence":"additional","affiliation":[{"name":"Georgia State University"},{"name":"Georgia State University"}]},{"given":"Desiree","family":"Wanders","sequence":"additional","affiliation":[{"name":"Georgia State University"},{"name":"Georgia State University"}]},{"given":"Rafaela G.","family":"Feresin","sequence":"additional","affiliation":[{"name":"Georgia State University"},{"name":"Georgia State University"}]},{"given":"Puja K.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Emory Clinical Cardiovascular Research Institute, Division of Cardiology"},{"name":"Emory University School of Medicine"}]},{"given":"Andrew T.","family":"Gewirtz","sequence":"additional","affiliation":[{"name":"Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences"},{"name":"Georgia State University"}]}],"issued":{"date-parts":[[2025,11,18]]},"member":"276","prefix":"10.1161","source":"Crossref","volume":"14","created":{"date-time":"2025-11-12T06:12:43Z","timestamp":1762927963000,"date-parts":[[2025,11,12]]},"indexed":{"date-time":"2025-11-19T08:49:34Z","timestamp":1763542174371,"date-parts":[[2025,11,19]]},"subject":[],"abstract":"$33","language":"en","relation":{},"resource":{"primary":{"URL":"https://www.ahajournals.org/doi/10.1161/JAHA.125.045515"}},"subtitle":[],"assertion":[{"name":"received","group":{"name":"publication_history","label":"Publication History"},"label":"Received","order":0,"value":"2025-08-10"},{"name":"accepted","group":{"name":"publication_history","label":"Publication History"},"label":"Accepted","order":2,"value":"2025-10-09"},{"name":"published","group":{"name":"publication_history","label":"Publication History"},"label":"Published","order":3,"value":"2025-11-11"}],"deposited":{"date-time":"2025-11-19T08:44:35Z","timestamp":1763541875000,"date-parts":[[2025,11,19]]},"issn-type":[{"type":"electronic","value":"2047-9980"}],"published":{"date-parts":[[2025,11,18]]},"publisher":"Ovid Technologies (Wolters Kluwer Health)","reference":[{"DOI":"10.1016/S0140-6736(16)31012-1","key":"e_1_3_2_2_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1093/eurheartj/ehz425","key":"e_1_3_2_3_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1161/CIRCULATIONAHA.116.024534","key":"e_1_3_2_4_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.jacc.2010.01.054","key":"e_1_3_2_5_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.jacc.2018.09.042","key":"e_1_3_2_6_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1161/JAHA.115.003064","key":"e_1_3_2_7_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1002/ejhf.1671","key":"e_1_3_2_8_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1210/en.2007-0920","key":"e_1_3_2_9_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1093/cvr/cvaa006","key":"e_1_3_2_10_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1161/JAHA.119.012865","key":"e_1_3_2_11_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.jacc.2017.05.047","key":"e_1_3_2_12_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.3390/ijms22073373","key":"e_1_3_2_13_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.3390/antiox11061212","key":"e_1_3_2_14_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1177/000331970005101003","key":"e_1_3_2_15_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/0140-6736(90)91656-u","key":"e_1_3_2_16_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":null,"key":"e_1_3_2_17_2","year":"2014","issue":null,"author":"Esselstyn CB","volume":"63","first-page":"356","unstructured":"Esselstyn CB Jr, Gendy G, Doyle J, Golubic M, Roizen MF. A way to reverse CAD? J Fam Pract. 2014;63:356–364b.","article-title":"A way to reverse CAD?","journal-title":"J Fam Pract","doi-asserted-by":null},{"DOI":"10.1371/journal.pone.0240722","key":"e_1_3_2_18_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.jcin.2015.03.045","key":"e_1_3_2_19_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1002/ccd.29237","key":"e_1_3_2_20_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1093/eurheartj/ehab282","key":"e_1_3_2_21_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1093/database/bat070","key":"e_1_3_2_22_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1007/978-1-4939-7030-8_6","key":"e_1_3_2_23_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1101/2025.01.14.632950","key":"e_1_3_2_24_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":"Najjar RS Mehta PK Gewirtz AT. An animal model of coronary microvascular dysfunction (CMD) in the female spontaneousoly hypertensive rat: the role of diet. 2025 bioRxiv:2025.2001.2014.632950. 10.1101/2025.01.14.632950.","article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1038/s41598-021-98401-1","key":"e_1_3_2_25_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/0006-8993(94)91969-0","key":"e_1_3_2_26_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1536/ihj.27.881","key":"e_1_3_2_27_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1161/01.res.53.6.767","key":"e_1_3_2_28_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1006/jmcc.1998.0904","key":"e_1_3_2_29_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1128/MCB.23.8.2871-2882.2003","key":"e_1_3_2_30_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1165/rcmb.2003-0384OC","key":"e_1_3_2_31_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1007/s11906-015-0550-4","key":"e_1_3_2_32_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1161/hypertensionaha.107.103523","key":"e_1_3_2_33_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.redox.2023.102820","key":"e_1_3_2_34_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.jacc.2018.10.094","key":"e_1_3_2_35_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1253/jcj.41.259","key":"e_1_3_2_36_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1002/clc.22863","key":"e_1_3_2_37_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.abb.2018.05.016","key":"e_1_3_2_38_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1111/bph.12676","key":"e_1_3_2_39_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1002/mnfr.201700053","key":"e_1_3_2_40_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1126/science.1058709","key":"e_1_3_2_41_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1038/nature12820","key":"e_1_3_2_42_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.3390/nu13072402","key":"e_1_3_2_43_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1152/physiolgenomics.00081.2016","key":"e_1_3_2_44_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.3791/65391","key":"e_1_3_2_45_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1152/ajpheart.00612.2012","key":"e_1_3_2_46_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1038/mt.2014.225","key":"e_1_3_2_47_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.3791/59406","key":"e_1_3_2_48_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1093/cvr/cvaa002","key":"e_1_3_2_49_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.jcin.2015.06.017","key":"e_1_3_2_50_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1067/mhj.2001.114198","key":"e_1_3_2_51_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1210/er.2001-0045","key":"e_1_3_2_52_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.redox.2013.05.003","key":"e_1_3_2_53_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1161/HYPERTENSIONAHA.113.02284","key":"e_1_3_2_54_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1152/ajpheart.00772.2001","key":"e_1_3_2_55_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1186/s40738-020-00074-3","key":"e_1_3_2_56_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1161/01.Hyp.0000046924.94886.Ef","key":"e_1_3_2_57_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.22358/jafs/66871/2006","key":"e_1_3_2_58_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.3390/cells12010093","key":"e_1_3_2_59_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1007/s00018-015-2021-0","key":"e_1_3_2_60_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.jnutbio.2023.109535","key":"e_1_3_2_61_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"},{"DOI":"10.1016/j.numecd.2022.03.015","key":"e_1_3_2_62_2","year":null,"issue":null,"author":null,"volume":null,"first-page":null,"unstructured":null,"article-title":null,"journal-title":null,"doi-asserted-by":"publisher"}],"short-title":[],"journal-issue":{"issue":"22","published-print":{"date-parts":[[2025,11,18]]}},"update-policy":"https://doi.org/10.1161/crossmarkpolicy","alternative-id":["10.1161/JAHA.125.045515"],"article-number":"e045515","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"original-title":[],"container-title":["Journal of the American Heart Association"],"published-print":{"date-parts":[[2025,11,18]]},"reference-count":61,"published-online":null,"references-count":61,"short-container-title":["JAHA"],"is-referenced-by-count":0},"unpaywall":{"doi":"10.1161/jaha.125.045515","is_oa":true,"title":"Prevention and Reversal of Hypertension‐Induced Coronary Microvascular Dysfunction by a Plant‐Based Diet","updated":"2025-12-01T01:08:31+00:00","published_date":"2025-11-12","best_oa_location":{"url":"https://doi.org/10.1161/jaha.125.045515","pmh_id":null,"url_for_pdf":null,"url_for_landing_page":"https://doi.org/10.1161/jaha.125.045515"}}},"created_at":"2025-12-08T12:24:58.509Z","updated_at":"2025-12-08T12:24:58.509Z","tags":[{"paper_doi":"10.1161/jaha.125.045515","tag_type":"category","value":"Cardiac & Cardiovascular Systems","value_numeric":null},{"paper_doi":"10.1161/jaha.125.045515","tag_type":"condition","value":"Coronary Microvascular Dysfunction","value_numeric":null},{"paper_doi":"10.1161/jaha.125.045515","tag_type":"condition","value":"Hypertension","value_numeric":null},{"paper_doi":"10.1161/jaha.125.045515","tag_type":"impact_flag","value":"limited_evidence","value_numeric":null},{"paper_doi":"10.1161/jaha.125.045515","tag_type":"modality","value":"Plant-Based Diet","value_numeric":null},{"paper_doi":"10.1161/jaha.125.045515","tag_type":"sex","value":"female","value_numeric":null},{"paper_doi":"10.1161/jaha.125.045515","tag_type":"study_design","value":"Preclinical Animal Study","value_numeric":null},{"paper_doi":"10.1161/jaha.125.045515","tag_type":"warning","value":"Causality of microbiota changes for coronary benefits was not supported by antibiotic experiments.","value_numeric":null},{"paper_doi":"10.1161/jaha.125.045515","tag_type":"warning","value":"Design label reflects a preclinical rat experiment and does not map to standard clinical study categories.","value_numeric":null},{"paper_doi":"10.1161/jaha.125.045515","tag_type":"warning","value":"The abstract does not report sample size or numeric outcome data.","value_numeric":null}],"summaries":{"what_studied":"Preclinical study in female Wistar-Kyoto and spontaneously hypertensive rats fed either a control refined diet or a plant-based diet (28% fruits, vegetables, nuts, legumes) from 4 weeks of age, with a subset of hypertensive rats switched to the plant-based diet at 28 weeks; coronary microvascular function was assessed at 28 and 40 weeks by coronary flow reserve and cardiac MRI, with vascular and tissue mechanistic assays.","key_result":"In hypertensive rats, the plant-based diet did not lower blood pressure but prevented development of coronary microvascular dysfunction and reversed established dysfunction; benefits were associated with improved endothelial nitric oxide synthase function, enhanced nitric oxide–mediated vascular smooth muscle signaling, and reduced left ventricular oxidative stress, inflammatory signaling, and fibrosis. The diet altered gut microbiota, but antibiotic experiments did not support a causal role in the coronary benefits.","limitations":"Preclinical rat model limits direct clinical applicability. Sample size and effect magnitudes were not reported in the abstract, and outcomes were presented without numeric data. The gut microbiota findings were inconclusive despite observed compositional changes.","practice_takeaway":"In a hypertensive rat model, a plant-based diet preserved and restored coronary microvascular function independent of blood pressure effects; this supports pursuing clinical trials in patients with coronary microvascular dysfunction, but clinical efficacy remains unproven."}}],"initialOffset":4,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"modality","value":"Plant-Based Diet"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Modalities","href":"/hub/tag/modality"},{"name":"Plant-Based Diet"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"modality","hub_tag_value":"Plant-Based Diet"}}}]]

Papers