2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:T5e8,Unplanned healthcare utilization events, including hospital readmissions and emergency room (ER) visits, are common in patients receiving outpatient parenteral antimicrobial therapy (OPAT). Little is known about patient adherence to therapy in this setting. This clinical trial evaluates the impact of a remote therapeutic monitoring (RTM) device with an integrated care platform on all-cause healthcare utilization in patients on OPAT. This prospective, open-label, non-randomized study enrolled patients discharged on OPAT to receive the IV Ensure RTM device compared to contemporaneous controls. The primary outcome was all-cause healthcare utilization, including hospital readmission or ER visit, assessed at day 90 post-discharge. Adherence to antimicrobial therapy was evaluated in the intervention group. A total of 81 patients were enrolled in the intervention and 131 patients constituted the control group. Both groups had similar baseline and OPAT characteristics. On multivariate Cox regression analysis, the RTM intervention was associated with a 39% reduction in all-cause healthcare utilization by day 60 (aHR 0.61, 95% CI 0.38-0.96, p=0.030) and a 38% reduction by day 90 (aHR 0.62, 95% CI 0.40-0.95, p=0.027). In the intervention group, the overall adherence reached a median of 94%, and 61.7% of patients maintained an adherence > 90% throughout their OPAT course. An RTM device with an integrated care platform significantly reduced all-cause healthcare utilization events in patients on OPAT.31:T86c,Abstract Background Unplanned healthcare utilization events, including hospital readmissions and emergency room (ER) visits, are common in patients receiving outpatient parenteral antimicrobial therapy (OPAT). Little is known about patient adherence to therapy in this setting. This clinical trial evaluates the impact of a remote therapeutic monitoring (RTM) device with an integrated care platform on all-cause healthcare utilization in patients on OPAT. Methods This prospective, open-label, non-randomized study enrolled patients discharged on OPAT to receive the IV Ensure RTM device compared to contemporaneous controls. The primary outcome was all-cause healthcare utilization, including hospital readmission or ER visit, assessed at day 90 post-discharge. Adherence to antimicrobial therapy was evaluated in the intervention group. Results A total of 81 patients were enrolled in the intervention and 131 patients constituted the control group. Both groups had similar baseline and OPAT characteristics. On multivariate Cox regression analysis, the RTM intervention was associated with a 39% reduction in all-cause healthcare utilization by day 60 (aHR 0.61, 95% CI 0.38-0.96, p=0.030) and a 38% reduction by day 90 (aHR 0.62, 95% CI 0.40-0.95, p=0.027). In the intervention group, the overall adherence reached a median of 94%, and 61.7% of patients maintained an adherence > 90% throughout their OPAT course. Conclusions An RTM device with an integrated care platform significantly reduced all-cause healthcare utilization events in patients on OPAT. 25:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Remote Monitoring: modality Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Remote Monitoring (modality). Clinician-written summaries and actionable practice insights. 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Both groups had similar baseline and OPAT characteristics. On multivariate Cox regression analysis, the RTM intervention was associated with a 39% reduction in all-cause healthcare utilization by day 60 (aHR 0.61, 95% CI 0.38-0.96, p=0.030) and a 38% reduction by day 90 (aHR 0.62, 95% CI 0.40-0.95, p=0.027). In the intervention group, the overall adherence reached a median of 94%, and 61.7% of patients maintained an adherence > 90% throughout their OPAT course.","abstract":"$30","keywords":[],"pubmed_id":"41502186","conclusions":"","publication_date":"2026-01-08T00:00:00"},"crossref":{"DOI":"10.1093/cid/ciag009","URL":"https://doi.org/10.1093/cid/ciag009","ISSN":["1058-4838","1537-6591"],"link":[{"URL":"https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciag009/66301308/ciag009.pdf","content-type":"application/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciag009/66301308/ciag009.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":null,"type":"journal-article","issue":null,"score":1,"title":["Evaluation of a Remote Therapeutic Monitoring (RTM) Device and Integrated Care Platform in Outpatient Parenteral Antimicrobial Therapy (OPAT)"],"author":[{"given":"Emily A","family":"Siegrist","sequence":"first","affiliation":[{"name":"Department of Pharmacy, OU Health , Oklahoma City, OK ,"}]},{"given":"Mitchell","family":"Berenson","sequence":"additional","affiliation":[{"name":"IV Ensure, Inc. , Dallas, TX ,"}]},{"given":"Justin D","family":"Dvorak","sequence":"additional","affiliation":[{"name":"Hudson College of Public Health, University of Oklahoma Health Campus , Oklahoma City, OK ,"}]},{"given":"Jacob K","family":"Dozier","sequence":"additional","affiliation":[{"name":"IV Ensure, Inc. , Dallas, TX ,"}]},{"given":"S Rae","family":"Wannier","sequence":"additional","affiliation":[{"name":"IV Ensure, Inc. , Dallas, TX ,"}]},{"given":"Rita Wilson","family":"Dib","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, College of Medicine, University of Oklahoma Health Campus , Oklahoma City, OK ,"}]},{"given":"Brian M","family":"Scott","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, College of Medicine, University of Oklahoma Health Campus , Oklahoma City, OK ,"}]},{"given":"Nayle","family":"Ibragimova","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, OU Health , Oklahoma City, OK ,"}]},{"given":"Debbie Nail","family":"Meyer","sequence":"additional","affiliation":[{"name":"IV Ensure, Inc. , Dallas, TX ,"}]},{"given":"Maria","family":"Alkozah","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, College of Medicine, University of Oklahoma Health Campus , Oklahoma City, OK ,"}]},{"given":"Michelle","family":"Salvaggio","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, College of Medicine, University of Oklahoma Health Campus , Oklahoma City, OK ,"}]},{"given":"Bryan P","family":"White","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, OU Health , Oklahoma City, OK ,"}]},{"given":"Bushra","family":"Siddique","sequence":"additional","affiliation":[{"name":"OU Health Edmond Medical Center , Edmond, OK ,"}]},{"given":"Sharanjeet","family":"Thind","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, College of Medicine, University of Oklahoma Health Campus , Oklahoma City, OK ,"}]},{"given":"Dale W","family":"Bratzler","sequence":"additional","affiliation":[{"name":"Hudson College of Public Health, University of Oklahoma Health Campus , Oklahoma City, OK ,"}]},{"given":"Joseph","family":"Sassine","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, College of Medicine, University of Oklahoma Health Campus , Oklahoma City, OK 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controls).","value_numeric":null}],"summaries":{"what_studied":"Prospective, open-label, non-randomized comparison of an RTM device with integrated care (IV Ensure) versus contemporaneous controls in patients discharged on OPAT, with all-cause healthcare utilization (readmission or ER visit) assessed through day 90 post-discharge; adherence was measured in the intervention group.","key_result":"Among 81 intervention and 131 control patients, the RTM intervention was associated with lower all-cause healthcare utilization by day 60 (aHR 0.61, 95% CI 0.38–0.96, p=0.030) and by day 90 (aHR 0.62, 95% CI 0.40–0.95, p=0.027). In the intervention group, median adherence was 94%, and 61.7% maintained >90% adherence throughout OPAT.","limitations":"Open-label, non-randomized design with contemporaneous controls. Adherence was assessed only in the intervention group. The abstract does not report absolute event counts for utilization outcomes.","practice_takeaway":"In OPAT programs, an RTM device with integrated care was associated with fewer readmissions/ER visits by 60–90 days and high adherence; interpret and apply with caution given the nonrandomized design."}}],"initialOffset":1,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"modality","value":"Remote Monitoring"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Modalities","href":"/hub/tag/modality"},{"name":"Remote Monitoring"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"modality","hub_tag_value":"Remote Monitoring"}}}]]

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