2f:I[703058,["/_next/static/immutable/chunks/3bhq_5eh1d760.js","/_next/static/immutable/chunks/1855-ogyi8eh4.js","/_next/static/immutable/chunks/2pfsjpn6k6zlg.js","/_next/static/immutable/chunks/26c7v3_3uwnwu.js","/_next/static/immutable/chunks/25a3ozcrvi1ff.js","/_next/static/immutable/chunks/2r4wx50nvjh_4.js","/_next/static/immutable/chunks/23fsw06hsi5b1.js","/_next/static/immutable/chunks/06_yt270h41rg.js","/_next/static/immutable/chunks/3ezsiz-7shkna.js","/_next/static/immutable/chunks/20x2y96ldu5wx.js","/_next/static/immutable/chunks/2lxntcm3pd1_h.js","/_next/static/immutable/chunks/00dgco8irq3jw.js","/_next/static/immutable/chunks/00nwe-kq0rboc.js","/_next/static/immutable/chunks/2051ffx3xzio9.js"],"PaperListPageClient"] 30:T608,Mother's own milk (MOM), appropriately fortified, provides optimal nutrition for hospitalized very low birth weight (VLBW [≤1500 g]) infants in the neonatal intensive care unit (NICU) and confers a myriad of other short- and long-term health benefits. Every family of a VLBW infant should receive information about the critical importance of MOM to the health of their infants and receive intensive support throughout the full course of their infant's hospitalization to achieve their personal lactation goals. Provision of pasteurized donor human milk (PDHM) is recommended when MOM is not available, insufficient in volume, or is contraindicated. PDHM should optimally be continued until the infant's risk to develop necrotizing enterocolitis is low (approximately 34-36 weeks' postmenstrual age). Preterm infant formula is recommended when MOM is not available and PDHM is either not available or the family declines use. Promotion of human milk and breastfeeding for VLBW infants requires access to efficient, effective, and comfortable double electric breast pumps in the hospital and at home and multidisciplinary and system-wide adoption of lactation support practices, including early and frequent milk expression, skin-to-skin care (SSC), and direct breastfeeding. Addressing social inequities in provision of human milk at the local level requires access to PDHM, peer lactation support, maximizing use of interpreter services as appropriate, and implementation of standardized approaches to identify and address unmet basic needs.31:T623,Mother’s own milk (MOM), appropriately fortified, provides optimal nutrition for hospitalized very low birth weight (VLBW [≤1500 g]) infants in the neonatal intensive care unit (NICU) and confers a myriad of other short- and long-term health benefits. Every family of a VLBW infant should receive information about the critical importance of MOM to the health of their infants and receive intensive support throughout the full course of their infant’s hospitalization to achieve their personal lactation goals. Provision of pasteurized donor human milk (PDHM) is recommended when MOM is not available, insufficient in volume, or is contraindicated. PDHM should optimally be continued until the infant’s risk to develop necrotizing enterocolitis is low (approximately 34–36 weeks’ postmenstrual age). Preterm infant formula is recommended when MOM is not available and PDHM is either not available or the family declines use. Promotion of human milk and breastfeeding for VLBW infants requires access to efficient, effective, and comfortable double electric breast pumps in the hospital and at home and multidisciplinary and system-wide adoption of lactation support practices, including early and frequent milk expression, skin-to-skin care (SSC), and direct breastfeeding. Addressing social inequities in provision of human milk at the local level requires access to PDHM, peer lactation support, maximizing use of interpreter services as appropriate, and implementation of standardized approaches to identify and address unmet basic needs.32:T43b,Abstract Atrial tachycardias (AT) represent an increasingly recognized cause of morbidity and mortality. Over the past decade, the mechanistic understanding and therapeutic concepts guiding AT treatment have undergone rapid progress. Catheter ablation has become the most effective therapy for maintaining sinus rhythm in patients with regular AT, while mapping and ablation concepts and technologies have improved significantly. Accordingly, international cardiac electrophysiology professional societies aimed at outlining best practices on the management of regular AT, with a special focus on indications, timing, and technical aspects of AT mapping and ablation. After reviewing and discussing available evidence, including a systematic literature review and meta-analysis, an expert writing group summarized current knowledge and practice and has proposed strategies in the here outlined 10-Point Plan for SMART-AT care (Standardized Management and Ablation Roadmap for Treatment of Patients with Atrial Tachycardia).33:Ta84,This update expands the 2020 American Cancer Society (ACS) cervical cancer screening guideline for average-risk women and individuals with a cervix who are at average risk, to include self-collection for human papillomavirus (HPV) testing and revised guidance for exiting cervical cancer screening. Self-collected vaginal specimens, a method of primary HPV testing, align with the ACS cervical cancer screening guideline. When clinician-collected cervical specimens are used for HPV testing, repeat screening is recommended every 5 years for those with a negative test. For self-collected vaginal specimens, the ACS endorses the following recommendations of the Enduring Consensus Cervical Cancer Screening and Management Guidelines Committee (of which it is a member): (1) primary HPV screening using clinician-collected cervical specimens is preferred, and self-collected vaginal specimens are acceptable for average-risk individuals aged 25-65 years; and (2) repeat testing in 3 years is recommended after a negative result on a self-collected HPV screening test. These recommendations apply only to combinations of collection devices and HPV assays approved by the US Food and Drug Administration for HPV testing in a clinical setting or at home. The rationale notes that the use of self-collected vaginal specimens can overcome barriers to screening for many patients, but most patients who test HPV-positive will require extra follow-up steps, and data on long-term, real-world effectiveness are limited. For certain high-risk individuals, clinician-collected samples are still recommended. Furthermore, in response to high rates of cervical cancer among individuals older than 65 years and with poor implementation of current exiting screening criteria, ACS has amended the 2020 guideline to recommend HPV testing at ages 60 and 65 years, with the last HPV test at an age no younger than 65 years as a requisite to exiting screening. The revised recommendation states: To qualify for discontinuation of screening, the ACS recommends an average-risk woman or an individual with a cervix at average risk have negative primary HPV tests (preferred) or negative co-testing using HPV tests and cytology (acceptable) at ages 60 and 65 years. If primary HPV tests or co-testing are not available, three consecutive negative cytology (Papanicolaou) tests at the recommended screening interval with the last test at age 65 years are acceptable. If self-collected vaginal specimens are used for HPV testing, the 3-year testing interval should be followed. Additional screening exit stipulations relate to women at higher risk because of prior abnormal test results or current immune suppression.34:Tb60,Abstract This update expands the 2020 American Cancer Society (ACS) cervical cancer screening guideline for average‐risk women and individuals with a cervix who are at average risk, to include self‐collection for human papillomavirus (HPV) testing and revised guidance for exiting cervical cancer screening. Self‐collected vaginal specimens, a method of primary HPV testing, align with the ACS cervical cancer screening guideline. When clinician‐collected cervical specimens are used for HPV testing, repeat screening is recommended every 5 years for those with a negative test. For self‐collected vaginal specimens, the ACS endorses the following recommendations of the Enduring Consensus Cervical Cancer Screening and Management Guidelines Committee (of which it is a member): (1) primary HPV screening using clinician‐collected cervical specimens is preferred, and self‐collected vaginal specimens are acceptable for average‐risk individuals aged 25–65 years; and (2) repeat testing in 3 years is recommended after a negative result on a self‐collected HPV screening test. These recommendations apply only to combinations of collection devices and HPV assays approved by the US Food and Drug Administration for HPV testing in a clinical setting or at home. The rationale notes that the use of self‐collected vaginal specimens can overcome barriers to screening for many patients, but most patients who test HPV‐positive will require extra follow‐up steps, and data on long‐term, real‐world effectiveness are limited. For certain high‐risk individuals, clinician‐collected samples are still recommended. Furthermore, in response to high rates of cervical cancer among individuals older than 65 years and with poor implementation of current exiting screening criteria, ACS has amended the 2020 guideline to recommend HPV testing at ages 60 and 65 years, with the last HPV test at an age no younger than 65 years as a requisite to exiting screening. The revised recommendation states: To qualify for discontinuation of screening, the ACS recommends an average‐risk woman or an individual with a cervix at average risk have negative primary HPV tests (preferred) or negative co‐testing using HPV tests and cytology (acceptable) at ages 60 and 65 years. If primary HPV tests or co‐testing are not available, three consecutive negative cytology (Papanicolaou) tests at the recommended screening interval with the last test at age 65 years are acceptable. If self‐collected vaginal specimens are used for HPV testing, the 3‐year testing interval should be followed. Additional screening exit stipulations relate to women at higher risk because of prior abnormal test results or current immune suppression. 35:T816,This Guideline covers the evaluation and treatment of patients with kidney and/or ureteral stones. The summary presented herein represents Part I of the III-part series dedicated to Surgical Management of Kidney and Ureteral Stones. Please refer to Parts II and III for additional information on this topic. This systematic review was conducted in 2 planned stages, including a search for systematic reviews followed by a search for primary literature. OVID was used to systematically search MEDLINE and EMBASE databases for articles evaluating surgical management of kidney and ureteral stones. The Panel selected control articles that were deemed relevant and the articles were compared with the literature search strategy output. The methodologist then updated the strategy as necessary to capture all control articles. Databases were searched for studies published from January 2000 through May 2025 (week 20). In addition to the MEDLINE and EMBASE databases searches, reference lists of included systematic reviews and primary literature were scanned for potentially useful studies. The Panel addressed adult and pediatric patients with kidney and/or ureteral stones for whom surgical intervention may be indicated. Each statement herein addressed a particular patient scenario for which the choice of surgical intervention was reviewed and justified. In addition, the Panel reviewed and analyzed the utility of specific surgical techniques, technologies, or medications aimed at improving patient outcomes. Selection of optimal treatment modalities for patients with kidney and/or ureteral stones is determined by patient factors, urinary tract anatomy, and stone characteristics and are guided by shared decision-making that additionally takes into account patient goals and preferences, resource availability, and physician expertise. This Guideline serves as a resource for clinicians and patients to provide the best available evidence on which to base discussions with patients in a shared decision-making process to arrive at appropriate treatment decisions.36:T845,The fungal diagnostic landscape is evolving; whereas previously, traditional culture-based methods dominated, most invasive fungal disease is now diagnosed with non-culture-based tests, including direct microscopy, antigen, antibody, and molecular assays, supported by histopathology and radiology. Access to and turnaround time of diagnostic tests and their clinical implementation varies across the UK. The British Society for Medical Mycology convened an expert group to update its 2015 best practice guidance. Guidance on histopathology and radiology investigations remain unchanged from the 2015 standards of care. For each mycological test, we include test-specific commentaries and accompanying tables, with expected turnaround times (sample collection to reporting). Based on recent evidence, new or stronger recommendations include use of Pneumocystis PCR; 1,3-β-D-glucan testing for suspected invasive candidiasis and Pneumocystis pneumonia; higher volume respiratory sample cultures; Aspergillus antigen or antibody-based testing in expanded clinically vulnerable populations, including patients in intensive care units and patients with chronic respiratory disease (including asthma); use of Candida PCR and Mucorales PCR in specific contexts; pan-fungal PCR and DNA sequencing for fungal identification from positive microscopy or histopathology specimens; and inclusion of posaconazole and isavuconazole in therapeutic antifungal monitoring recommendations. We discuss integration of diagnostic tests with antifungal stewardship and common clinical scenarios. Although recommendations focus on adults and UK practice, use in paediatric populations and worldwide applicability is discussed. Recommendations are presented as auditable standards to facilitate implementation and quality improvement measures. An emphasis on integration of combined diagnostics with antifungal stewardship and clinical pathways extends guideline relevance beyond microbiology laboratories to clinicians investigating patients with multimorbidity and suspected fungal disease within increasingly complex health-care systems.37:T86a,Codeveloped by the American Heart Association and the American Academy of Pediatrics, this publication presents the 2025 guidelines for basic life support during cardiopulmonary resuscitation and emergency cardiovascular care of the pediatric patient, excluding the newborn infant, and represents the first comprehensive update of treatment recommendations since 2020. Incorporating the results of structured evidence reviews from the International Liaison Committee on Resuscitation, these guidelines are for lay rescuers and health care professionals with recommendations designed to improve survival from sudden cardiac arrest and acute life-threatening cardiopulmonary problems. Existing guidelines remain relevant unless specifically updated in this publication. Topics reviewed include the initiation of cardiopulmonary resuscitation; pulse check; components of high-quality cardiopulmonary resuscitation; chest compression technique; support surfaces for cardiopulmonary resuscitation; opening the airway; coordination of shock and cardiopulmonary resuscitation; types of defibrillators or automated external defibrillators; defibrillator paddle or pad size, type, position; treatment of inadequate breathing with a pulse; and foreign-body airway obstruction. Key topics that are new, are substantially revised, or have significant new literature include the elimination of 2-finger chest compressions in infants due to ineffectiveness of achieving proper depth with a recommendation of 1-hand or 2 thumb-encircling hands technique; the immediate application and use of an automated external defibrillator with a pediatric attenuator if available for cardiac arrest; and in infants with severe foreign-body airway obstruction repeated cycles of 5 back blows alternating with 5 chest thrusts (no abdominal thrusts), and in children with severe foreign-body airway obstruction repeated cycles of 5 back blows alternating with 5 abdominal thrusts. Key Words: AHA Scientific Statements • cardiopulmonary resuscitation • chest compressions • defibrillator • foreign body airway obstruction • heart arrest • shockable rhythm • ventilation.38:T89f,Codeveloped by the American Heart Association and the American Academy of Pediatrics, this publication presents the 2025 guidelines for basic life support during cardiopulmonary resuscitation and emergency cardiovascular care of the pediatric patient, excluding the newborn infant, and represents the first comprehensive update of treatment recommendations since 2020. Incorporating the results of structured evidence reviews from the International Liaison Committee on Resuscitation, these guidelines are for lay rescuers and health care professionals with recommendations designed to improve survival from sudden cardiac arrest and acute life-threatening cardiopulmonary problems. Existing guidelines remain relevant unless specifically updated in this publication. Topics reviewed include the initiation of cardiopulmonary resuscitation; pulse check; components of high-quality cardiopulmonary resuscitation; chest compression technique; support surfaces for cardiopulmonary resuscitation; opening the airway; coordination of shock and cardiopulmonary resuscitation; types of defibrillators or automated external defibrillators; defibrillator paddle or pad size, type, position; treatment of inadequate breathing with a pulse; and foreign-body airway obstruction. Key topics that are new, are substantially revised, or have significant new literature include the elimination of 2-finger chest compressions in infants due to ineffectiveness of achieving proper depth with a recommendation of 1-hand or 2 thumb–encircling hands technique; the immediate application and use of an automated external defibrillator with a pediatric attenuator if available for cardiac arrest; and in infants with severe foreign-body airway obstruction repeated cycles of 5 back blows alternating with 5 chest thrusts (no abdominal thrusts), and in children with severe foreign-body airway obstruction repeated cycles of 5 back blows alternating with 5 abdominal thrusts. Key Words: AHA Scientific Statements • cardiopulmonary resuscitation • chest compressions • defibrillator • foreign body airway obstruction • heart arrest • shockable rhythm • ventilation39:T4ab,This manuscript provides expert recommendations on the role of allogeneic haematopoietic cell transplantation (allo-HCT) for cutaneous T-cell lymphoma (CTCL), specifically mycosis fungoides (MF) and Sezary syndrome (SS). Critical aspects such as patient selection, timing, and bridging therapy are addressed, as well as donor source, conditioning regimens and post-transplant management. These consensus guidelines are based on a thorough literature review and discussions among leading dermatologists and haematologists. These recommendations aim to harmonize clinical practice towards improving patient outcomes in these rare but aggressive lymphomas. It is of critical importance to consider allo-HCT early in the management of eligible patients with high-risk disease. Advanced stage, large-cell transformation, relapsed or refractory disease following systemic treatment, and N3-stage lymph node involvement are indicators that should trigger consultation with a transplant haematologist in parallel with a donor search. Early interaction between dermatologists and transplant haematologists is vital to avoiding delays, which can significantly impact post-transplant outcomes and survival.3a:T4ed,AbstractThis manuscript provides expert recommendations on the role of allogeneic haematopoietic cell transplantation (allo‐HCT) for cutaneous T‐cell lymphoma (CTCL), specifically mycosis fungoides (MF) and Sezary syndrome (SS). Critical aspects such as patient selection, timing, and bridging therapy are addressed, as well as donor source, conditioning regimens and post‐transplant management. These consensus guidelines are based on a thorough literature review and discussions among leading dermatologists and haematologists. These recommendations aim to harmonize clinical practice towards improving patient outcomes in these rare but aggressive lymphomas. It is of critical importance to consider allo‐HCT early in the management of eligible patients with high‐risk disease. Advanced stage, large‐cell transformation, relapsed or refractory disease following systemic treatment, and N3‐stage lymph node involvement are indicators that should trigger consultation with a transplant haematologist in parallel with a donor search. Early interaction between dermatologists and transplant haematologists is vital to avoiding delays, which can significantly impact post‐transplant outcomes and survival.3b:T716,Microfocused ultrasound with visualization (MFU-V) is well established for noninvasive lifting of the face, neck, and décolleté. U.S. FDA clearance was recently granted for treatment of the abdomen and upper arms, supported by favorable safety data and emerging evidence of efficacy of its use to address skin and soft tissue laxity in body regions. Guidance on best practices for these additional indications is desirable. This consensus aims to provide evidence-based and practice-informed recommendations supporting safe, effective, and reproducible MFU-V treatments for the additional body indications. An international, multidisciplinary panel of aesthetic experts developed consensus recommendations for MFU-V treatment of additional body areas based on clinical evidence, expert experience, and structured virtual discussions. This global expert consensus affirms MFU-V as a safe and effective noninvasive modality for treating mild to moderate skin and soft tissue laxity in the abdomen and upper arms. Three key domains were identified as critical to optimizing outcomes: patient selection, treatment planning, and expectation management. Ideal candidates are those with mild to moderate laxity and target tissues located at treatable depths. Real-time ultrasound imaging was emphasized for accurate targeting, anatomical safety, and treatment precision. The panel developed practical treatment protocols for the abdomen and upper arms, including recommended treatment zones, line densities, and transducer depths tailored to tissue characteristics. Safe and effective MFU-V outcomes rely on real-time ultrasound visualization, thoughtful patient selection, expectation management, and anatomically guided treatment. Continued research is needed to refine protocols and guide emerging body applications.3c:T8a6,ABSTRACTBackgroundMicrofocused ultrasound with visualization (MFU‐V) is well established for noninvasive lifting of the face, neck, and décolleté. U.S. FDA clearance was recently granted for treatment of the abdomen and upper arms, supported by favorable safety data and emerging evidence of efficacy of its use to address skin and soft tissue laxity in body regions. Guidance on best practices for these additional indications is desirable.AimsThis consensus aims to provide evidence‐based and practice‐informed recommendations supporting safe, effective, and reproducible MFU‐V treatments for the additional body indications.MethodsAn international, multidisciplinary panel of aesthetic experts developed consensus recommendations for MFU‐V treatment of additional body areas based on clinical evidence, expert experience, and structured virtual discussions.ResultsThis global expert consensus affirms MFU‐V as a safe and effective noninvasive modality for treating mild to moderate skin and soft tissue laxity in the abdomen and upper arms. Three key domains were identified as critical to optimizing outcomes: patient selection, treatment planning, and expectation management. Ideal candidates are those with mild to moderate laxity and target tissues located at treatable depths. Real‐time ultrasound imaging was emphasized for accurate targeting, anatomical safety, and treatment precision. The panel developed practical treatment protocols for the abdomen and upper arms, including recommended treatment zones, line densities, and transducer depths tailored to tissue characteristics.ConclusionSafe and effective MFU‐V outcomes rely on real‐time ultrasound visualization, thoughtful patient selection, expectation management, and anatomically guided treatment. Continued research is needed to refine protocols and guide emerging body applications.25:[[["$","script","0",{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"{\"@context\":\"https://schema.org\",\"@type\":\"CollectionPage\",\"name\":\"Guideline: study design Research & Clinical Takeaways\",\"description\":\"Explore peer-reviewed papers on Guideline (study design). Clinician-written summaries and actionable practice insights. 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Report","journal_title":"Pediatrics","journal_issn":"0031-4005","published_at":"2026-01-12T00:00:00.000Z","url":"https://doi.org/10.1542/peds.2025-073625","source_score":18,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2026-01-17","doi":"10.1542/peds.2025-073625","days":"7","issn":"0031-4005","rank":"5","field":"Clinical Medicine","score":"18","category":"Pediatrics","categories":["Pediatrics"],"_categories":["Pediatrics"]},"pubmed":{"doi":"10.1542/peds.2025-073625","title":"Promoting Human Milk and Breastfeeding for the Very Low Birth Weight Infant: Clinical 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G.","family":"Parker","sequence":"first","affiliation":[{"name":"1Department of Pediatrics, UMass Chan School of Medicine, Worcester, Massachusetts"}]},{"given":"Lisa","family":"Stellwagen","sequence":"additional","affiliation":[{"name":"2Department of Pediatrics, University of California San Diego School of Medicine, La Jolla, California"}]},{"given":"Emily R.","family":"Miller","sequence":"additional","affiliation":[{"name":"3Division of Neonatology, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio"}]},{"given":"Lawrence","family":"Noble","sequence":"additional","affiliation":[{"name":"4Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, New York"},{"name":"5New York City Health+Hospitals/Elmhurst, Elmhurst, New York"}]},{"given":"Mark R.","family":"Corkins","sequence":"additional","affiliation":[{"name":"6Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The University of Tennessee Health Science Center, Memphis, Tennessee"}]},{"given":"Mark L.","family":"Hudak","sequence":"additional","affiliation":[{"name":"7 Department of Pediatrics, University of Florida College of Medicine – Jacksonville, Florida"}]},{"given":null,"family":null,"sequence":"additional","affiliation":[]},{"given":"Eric","family":"Eichenwald","sequence":"additional","affiliation":[]},{"given":"Namasivayam","family":"Ambalavanan","sequence":"additional","affiliation":[]},{"given":"Charleta","family":"Guillory","sequence":"additional","affiliation":[]},{"given":"Mark L","family":"Hudak","sequence":"additional","affiliation":[]},{"given":"David","family":"Kaufman","sequence":"additional","affiliation":[]},{"given":"Camilia","family":"Martin","sequence":"additional","affiliation":[]},{"given":"Ashley","family":"Lucke","sequence":"additional","affiliation":[]},{"given":"Margaret G","family":"Parker","sequence":"additional","affiliation":[]},{"given":"Arun","family":"Pramanik","sequence":"additional","affiliation":[]},{"given":"Kelly","family":"Wade","sequence":"additional","affiliation":[]},{"given":null,"family":null,"sequence":"additional","affiliation":[]},{"given":"Maya","family":"Bunik","sequence":"additional","affiliation":[]},{"given":"Temitope","family":"Awelewa","sequence":"additional","affiliation":[]},{"given":"Emily","family":"Hannon","sequence":"additional","affiliation":[]},{"given":"Sahira","family":"Long","sequence":"additional","affiliation":[]},{"given":"Lakshmy","family":"Vaidyanathan","sequence":"additional","affiliation":[]},{"given":"Tara","family":"Williams","sequence":"additional","affiliation":[]},{"given":null,"family":null,"sequence":"additional","affiliation":[]},{"given":"Mark R","family":"Corkins","sequence":"additional","affiliation":[]},{"given":"Cynthia L","family":"Blanco","sequence":"additional","affiliation":[]},{"given":"Catherine","family":"Larson-Nath","sequence":"additional","affiliation":[]},{"given":"Rebecka","family":"Peebles","sequence":"additional","affiliation":[]},{"given":"Amy L H","family":"Peterson","sequence":"additional","affiliation":[]},{"given":"Parminder","family":"Suchdev","sequence":"additional","affiliation":[]},{"given":"Jennifer Woo","family":"Baidal","sequence":"additional","affiliation":[]}],"issued":{"date-parts":[[2026,1,12]]},"member":"417","prefix":"10.1542","source":"Crossref","volume":null,"created":{"date-time":"2026-01-12T00:03:07Z","timestamp":1768176187000,"date-parts":[[2026,1,12]]},"indexed":{"date-time":"2026-01-12T02:38:56Z","timestamp":1768185536884,"date-parts":[[2026,1,12]]},"subject":[],"abstract":"$31","language":"en","relation":{},"resource":{"primary":{"URL":"https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2025-073625/206082/Promoting-Human-Milk-and-Breastfeeding-for-the"}},"subtitle":[],"deposited":{"date-time":"2026-01-12T00:03:45Z","timestamp":1768176225000,"date-parts":[[2026,1,12]]},"issn-type":[{"type":"print","value":"0031-4005"},{"type":"electronic","value":"1098-4275"}],"published":{"date-parts":[[2026,1,12]]},"publisher":"American Academy of Pediatrics (AAP)","reference":[{"DOI":"10.1016/j.ajcnut.2022.11.027","key":"2026011119030424200_r1","year":"2023","issue":"Suppl 1)(suppl 1","author":"Smilowitz","volume":"117","first-page":"S28","unstructured":null,"article-title":"Ecologies, synergies, and biological systems shaping human milk composition-a report from “Breastmilk Ecology: Genesis of Infant Nutrition (BEGIN)” Working Group 2","journal-title":"Am J Clin Nutr.","doi-asserted-by":"crossref"},{"DOI":"10.1016/j.pcl.2012.10.002","key":"2026011119030424200_r2","year":"2013","issue":"1","author":"Ballard","volume":"60","first-page":"49","unstructured":null,"article-title":"Human milk composition: nutrients and bioactive factors","journal-title":"Pediatr Clin North Am.","doi-asserted-by":"crossref"},{"DOI":"10.1001/jamapediatrics.2019.2645","key":"2026011119030424200_r3","year":"2019","issue":"10","author":"Parker","volume":"173","first-page":"961","unstructured":null,"article-title":"National trends in the provision of human milk at 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Over the past decade, the mechanistic understanding and therapeutic concepts guiding AT treatment have undergone rapid progress. Catheter ablation has become the most effective therapy for maintaining sinus rhythm in patients with regular AT, while mapping and ablation concepts and technologies have improved significantly. Accordingly, international cardiac electrophysiology professional societies aimed at outlining best practices on the management of regular AT, with a special focus on indications, timing, and technical aspects of AT mapping and ablation. After reviewing and discussing available evidence, including a systematic literature review and meta-analysis, an expert writing group summarized current knowledge and practice and has proposed strategies in the here outlined 10-Point Plan for SMART-AT care (Standardized Management and Ablation Roadmap for Treatment of Patients with Atrial Tachycardia).","keywords":["Atrial fibrillation","Atrial flutter","Atrial tachycardia","Consensus statement","Electroanatomical mapping","Electrocardiogram","Focal atrial tachycardia","Localized reentrant atrial tachycardia","Macro-reentrant atrial tachycardia","Pulsed-field ablation","Radiofrequency ablation"],"pubmed_id":"41435855","conclusions":"","publication_date":"2025-12-24T00:00:00"},"crossref":{"DOI":"10.1093/europace/euaf324","URL":"https://doi.org/10.1093/europace/euaf324","ISSN":["1099-5129","1532-2092"],"link":[{"URL":"https://academic.oup.com/europace/advance-article-pdf/doi/10.1093/europace/euaf324/66118552/euaf324.pdf","content-type":"application/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https://academic.oup.com/europace/article-pdf/27/12/euaf324/66118552/euaf324.pdf","content-type":"application/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https://academic.oup.com/europace/article-pdf/27/12/euaf324/66118552/euaf324.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":null,"type":"journal-article","issue":"12","score":1,"title":["Management of patients with atrial tachycardia: a clinical consensus statement of the European Heart Rhythm Association (EHRA) of the ESC, endorsed by the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), the Latin American Heart Rhythm Society (LAHRS), and the Association for European Paediatric and Congenital Cardiology (AEPC)"],"author":[{"given":"Christian","family":"Meyer","sequence":"first","affiliation":[{"name":"Division of Cardiology, Angiology, Intensive Care Medicine, EVK Düsseldorf, cNEP, cardiac Neuro- and Electrophysiology Research Consortium , Kirchfeldstrasse 40, 40217 Düsseldorf ,"},{"name":"Institute of Neural and Sensory Physiology, cNEP, Cardiac Neuro- and Electrophysiology Research Consortium, Medical Faculty, Heinrich Heine University Düsseldorf , Universitätsstrasse 1, 40225 Düsseldorf ,"}]},{"given":"Ann-Kathrin","family":"Kahle","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Angiology, Intensive Care Medicine, EVK Düsseldorf, cNEP, cardiac Neuro- and Electrophysiology Research Consortium , Kirchfeldstrasse 40, 40217 Düsseldorf ,"},{"name":"Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, University Hospital Düsseldorf , Düsseldorf ,"}]},{"given":"Nikolaos","family":"Dagres","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Intensive Care Medicine, German Heart Center of the Charite , Berlin ,"}]},{"given":"Nicolas","family":"Derval","sequence":"additional","affiliation":[{"name":"IHU LIRYC, Electrophysiology and Heart Modeling Institute, Cardiac Electrophysiology and Stimulation Department, Fondation Bordeaux Université and Bordeaux University Hospital (CHU) , Pessac-Bordeaux ,"}]},{"given":"Thomas A","family":"Dewland","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, University of California , San Francisco, CA ,"}]},{"given":"Fabrizio","family":"Drago","sequence":"additional","affiliation":[{"name":"Paediatric Cardiology and Cardiac Arrhythmias Complex Unit, Department of Paediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital and Research Institute , Rome ,"}]},{"given":"Lars","family":"Eckardt","sequence":"additional","affiliation":[{"name":"Department for Cardiology II: Electrophysiology, University Hospital Münster , Münster ,"}]},{"given":"Antonio","family":"Frontera","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Cardiology III, Great Metropolitan Hospital Niguarda , Milan ,"}]},{"given":"Edward P","family":"Gerstenfeld","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, University of California , San Francisco, CA ,"}]},{"given":"Carina","family":"Hardy","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Heart Institute (InCor), University of Sao Paulo Medical School , Sao Paulo ,"}]},{"given":"Pierre","family":"Jais","sequence":"additional","affiliation":[{"name":"IHU LIRYC, Electrophysiology and Heart Modeling Institute, Cardiac Electrophysiology and Stimulation Department, Fondation Bordeaux Université and Bordeaux University Hospital (CHU) , Pessac-Bordeaux ,"}]},{"given":"Jonathan","family":"Kalman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Royal Melbourne Hospital , Melbourne ,"},{"name":"Department of Medicine, University of Melbourne and Baker Research Institute , Melbourne ,"}]},{"given":"Peter M","family":"Kistler","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Alfred Hospital , Melbourne ,"},{"name":"Department of Clinical Research, The Baker Heart and Diabetes Research Institute , Melbourne ,"},{"name":"Department of Medicine, Nursing and Health Sciences, University of Melbourne , Parkville, Melbourne ,"},{"name":"Department of Cardiology, Royal Melbourne Hospital , Parkville, Melbourne ,"}]},{"given":"Claire","family":"Martin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Royal Papworth Hospital NHS Foundation Trust and Department of Medicine, University of Cambridge , Cambridge ,"}]},{"given":"Helmut","family":"Pürerfellner","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Cardiology, Angiology and Intensive Care Medicine, Ordensklinikum Linz Elisabethinen , Linz ,"}]},{"given":"Masateru","family":"Takigawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Advanced Arrhythmia Research, Institute of Science TOKYO , Tokyo ,"}]},{"given":"Tom","family":"Wong","sequence":"additional","affiliation":[{"name":"Cardiology Department, Royal Brompton and Harefield Hospitals, Guy's and St Thomas’ NHS Trust , London ,"}]},{"given":"Katja","family":"Zeppenfeld","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Center , Leiden 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To exit screening, ensure negative primary HPV tests (preferred) or co-tests at ages 60 and 65 with the last at ≥65, and follow additional stipulations for higher-risk individuals."}},{"doi":"10.1097/ju.0000000000004842","pmid":"41263323","title":"Surgical Management of Kidney and Ureteral Stones: AUA Guideline (2026) Part I: Evaluation and Treatment of Patients With Kidney and/or Ureteral Stones","journal_title":"Journal of Urology","journal_issn":"0022-5347","published_at":"2025-11-20T00:00:00.000Z","url":"https://doi.org/10.1097/ju.0000000000004842","source_score":23,"is_retracted":false,"is_open_access":false,"raw_metadata":{"ooir":{"day":"2026-01-11","doi":"10.1097/ju.0000000000004842","days":"14","issn":"0022-5347","rank":"5","field":"Clinical Medicine","score":"23","category":"Urology & Nephrology","categories":["Urology & Nephrology"],"_categories":["Urology & Nephrology"]},"pubmed":{"doi":"10.1097/JU.0000000000004842","title":"Surgical Management of Kidney and Ureteral Stones: AUA Guideline (2026) Part I: Evaluation and Treatment of Patients With Kidney and/or Ureteral Stones.","journal":"The Journal of urology","methods":"","results":"The Panel addressed adult and pediatric patients with kidney and/or ureteral stones for whom surgical intervention may be indicated. 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provided.","value_numeric":null}],"summaries":{"what_studied":"A 2025 update of pediatric basic life support guidelines (excluding newborns) for lay rescuers and health professionals, incorporating ILCOR evidence reviews and revising selected 2020 recommendations.","key_result":"Key changes: eliminate 2-finger chest compressions in infants in favor of 1-hand or 2 thumb-encircling techniques; apply an AED immediately with a pediatric attenuator if available; for severe foreign-body airway obstruction, infants receive repeated cycles of 5 back blows alternating with 5 chest thrusts (no abdominal thrusts), and children receive repeated cycles of 5 back blows alternating with 5 abdominal thrusts.","limitations":"Abstract does not provide outcome data, effect sizes, or strength-of-recommendation grading; scope excludes newborn infants.","practice_takeaway":"For infants, use 1-hand or 2-thumb encircling compressions (not 2-finger) and attach an AED immediately, using a pediatric attenuator 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In severe choking, give infants repeated 5 back blows alternating with 5 chest thrusts (no abdominal thrusts) and children repeated 5 back blows alternating with 5 abdominal thrusts."}},{"doi":"10.1111/jdv.70042","pmid":"41031482","title":"Allogeneic haematopoietic cell transplant in cutaneous T‐cell lymphomas: Recommendations from the EBMT PH&G Committee","journal_title":"Journal of the European Academy of Dermatology and Venereology","journal_issn":"0926-9959","published_at":"2025-10-01T00:00:00.000Z","url":"https://doi.org/10.1111/jdv.70042","source_score":1,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2025-10-05","doi":"10.1111/jdv.70042","days":"7","issn":"0926-9959","rank":"10","field":"Clinical Medicine","score":"1","category":"Dermatology","categories":["Dermatology"],"_categories":["Dermatology"]},"pubmed":{"doi":"10.1111/jdv.70042","title":"Allogeneic haematopoietic cell transplant in cutaneous T-cell lymphomas: Recommendations from the EBMT PH&G 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rather than a single trial.","value_numeric":null}],"summaries":{"what_studied":"Expert consensus guidance from the EBMT PH&G Committee on when and how to use allogeneic haematopoietic cell transplantation for cutaneous T‑cell lymphomas (mycosis fungoides and Sézary syndrome), covering referral criteria, timing/bridging, donor selection, conditioning/GVHD prophylaxis, and post‑transplant care.","key_result":"In the CUTALLO propensity‑matched prospective study (n=99), allo‑HCT prolonged PFS to 9.0 months vs 3.0 months with conventional therapy (HR 0.38, 95% CI 0.21–0.69; p<0.0001). Historical/pooled benchmarks for allo‑HCT show 5‑year OS 38% and PFS 26% (EBMT registry), and OS 51% at 1 year and 40% at 3 years with PFS 42% at 1 year and 33% at 3 years (meta‑analysis).","limitations":"Recommendations rest largely on retrospective series, registry analyses, and small prospective cohorts, with heterogeneous conditioning, donor sources, and peri‑transplant practices. Evidence for haploidentical donors, modern GVHD prophylaxis (e.g., PTCy), MRD monitoring, and maintenance strategies remains limited or inconclusive.","practice_takeaway":"Refer high‑risk MF/SS early; aim for CR or deep response (VGPR or mSWAT <10) before RIC allo‑HCT, prefer MRD/MUD donors, and observe a 6‑week washout after pre‑HCT mogamulizumab. Manage relapse with immunosuppression taper and DLI, adding site‑directed therapy or TSEB as indicated; routine post‑HCT MRD monitoring or maintenance is not recommended."}},{"doi":"10.1111/jocd.70449","pmid":"40995829","title":"Microfocused Ultrasound With Visualization for Body Indications: A Global Expert Consensus on Best Practices for Treatment of the Abdomen and Arms","journal_title":"Journal of Cosmetic Dermatology","journal_issn":"1473-2130","published_at":"2025-09-25T00:00:00.000Z","url":"https://doi.org/10.1111/jocd.70449","source_score":1,"is_retracted":false,"is_open_access":true,"raw_metadata":{"ooir":{"day":"2025-10-01","doi":"10.1111/jocd.70449","days":"7","issn":"1473-2130","rank":"9","field":"Clinical Medicine","score":"1","category":"Dermatology","categories":["Dermatology"],"_categories":["Dermatology"]},"pubmed":{"doi":"10.1111/jocd.70449","title":"Microfocused Ultrasound With Visualization for Body Indications: A Global Expert Consensus on Best Practices for Treatment of the Abdomen and Arms.","journal":"Journal of cosmetic dermatology","methods":"","results":"This global expert consensus affirms MFU-V as a safe and effective noninvasive modality for treating mild to moderate skin and soft tissue laxity in the abdomen and upper arms. Three key domains were identified as critical to optimizing outcomes: patient selection, treatment planning, and expectation management. Ideal candidates are those with mild to moderate laxity and target tissues located at treatable depths. Real-time ultrasound imaging was emphasized for accurate targeting, anatomical safety, and treatment precision. The panel developed practical treatment protocols for the abdomen and upper arms, including recommended treatment zones, line densities, and transducer depths tailored to tissue characteristics.","abstract":"$3b","keywords":["MFU‐V","body contouring","consensus","energy‐based device","real‐time visualization","real‐world evidence","skin laxity"],"pubmed_id":"40995829","conclusions":"Safe and effective MFU-V outcomes rely on real-time ultrasound visualization, thoughtful patient selection, expectation management, and anatomically guided treatment. Continued research is needed to refine protocols and guide emerging body applications.","publication_date":"2025-09-25T00:00:00"},"crossref":{"DOI":"10.1111/jocd.70449","URL":"https://doi.org/10.1111/jocd.70449","ISSN":["1473-2130","1473-2165"],"link":[{"URL":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/jocd.70449","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"page":null,"type":"journal-article","issue":"10","score":1,"title":["Microfocused Ultrasound With Visualization for Body Indications: A Global Expert Consensus on Best Practices for Treatment of the Abdomen and Arms"],"author":[{"given":"Frank","family":"Lin","sequence":"first","affiliation":[{"name":"Monash University Clayton Victoria Australia"}]},{"given":"Vasanop","family":"Vachiramon","sequence":"additional","affiliation":[{"name":"Division of Dermatology Faculty of Medicine Ramathibodi Hospital, Mahidol University Bangkok Thailand"}]},{"given":"Gabriela","family":"Casabona","sequence":"additional","affiliation":[{"name":"Ocean Clinic Marbella Málaga Spain"}]},{"given":"Jessie","family":"Cheung","sequence":"additional","affiliation":[{"name":"Cheung Aesthetics & Wellness Willowbrook Illinois USA"}]},{"given":"Ana Lúcia Gonzaga","family":"da Cunha","sequence":"additional","affiliation":[{"name":"Albert Einstein Teaching and Research Center São Paulo Brazil"}]},{"given":"Tatjana","family":"Pavicic","sequence":"additional","affiliation":[{"name":"Private Practice for Dermatology & Aesthetics Dr. Tatjana Pavicic Munich Germany"}]},{"given":"Julieta","family":"Spada","sequence":"additional","affiliation":[{"name":"Spada Dermatology & Aesthetics Buenos Aires Argentina"}]},{"given":"Sabrina","family":"Fabi","sequence":"additional","affiliation":[{"name":"University of California San Diego California USA"}]}],"issued":{"date-parts":[[2025,9,25]]},"member":"311","prefix":"10.1111","source":"Crossref","volume":"24","archive":["Portico"],"created":{"date-time":"2025-09-25T10:30:57Z","timestamp":1758796257000,"date-parts":[[2025,9,25]]},"indexed":{"date-time":"2025-09-26T00:15:23Z","timestamp":1758845723744,"date-parts":[[2025,9,26]]},"license":[{"URL":"http://creativecommons.org/licenses/by/4.0/","start":{"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000,"date-parts":[[2025,9,25]]},"delay-in-days":0,"content-version":"vor"}],"subject":[],"abstract":"$3c","language":"en","relation":{},"resource":{"primary":{"URL":"https://onlinelibrary.wiley.com/doi/10.1111/jocd.70449"}},"subtitle":[],"assertion":[{"name":"received","group":{"name":"publication_history","label":"Publication History"},"label":"Received","order":0,"value":"2025-06-16"},{"name":"accepted","group":{"name":"publication_history","label":"Publication History"},"label":"Accepted","order":2,"value":"2025-09-09"},{"name":"published","group":{"name":"publication_history","label":"Publication History"},"label":"Published","order":3,"value":"2025-09-25"}],"deposited":{"date-time":"2025-09-25T10:31:00Z","timestamp":1758796260000,"date-parts":[[2025,9,25]]},"issn-type":[{"type":"print","value":"1473-2130"},{"type":"electronic","value":"1473-2165"}],"published":{"date-parts":[[2025,9,25]]},"publisher":"Wiley","reference":[{"DOI":null,"key":"e_1_2_10_2_1","year":"2019","issue":"5","author":"Fabi S. 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durability beyond ~6 months is uncertain.","value_numeric":null},{"paper_doi":"10.1111/jocd.70449","tag_type":"warning","value":"Industry funding and author financial relationships with the device manufacturer may introduce bias.","value_numeric":null}],"summaries":{"what_studied":"An international, multidisciplinary panel developed consensus recommendations for using microfocused ultrasound with visualization (MFU‑V; Ultherapy/Ultherapy PRIME) to treat mild to moderate skin and soft tissue laxity of the abdomen and upper arms, based on published clinical evidence, expert experience, and structured virtual discussions.","key_result":"The panel affirmed MFU‑V as a safe, effective noninvasive option, citing three abdominal studies (n=54) and five upper‑arm studies (n=113) showing clinician‑ and patient‑reported improvements with no serious or unexpected adverse events, with effects often sustained for 6 months or longer after maximal improvement.","limitations":"Recommendations derive from expert consensus and small prospective studies; large, comparative trials and longer follow‑up are lacking. The work was funded by Merz Aesthetics, and all panelists reported financial relationships with the device manufacturer.","practice_takeaway":"Use real‑time ultrasound to individualize depth and density: abdomen typically treated with a 12‑column (2×4 cm) grid delivering a median 720 lines using dual‑depth (4.5 and 3.0 mm) with optional 1.5 mm for crepiness, avoiding the umbilicus. For upper arms, treat only the middle third with a 6‑column grid per region and a median 240 lines, using 1.5/3.0 mm anteriorly and 3.0/4.5 mm posteriorly, with caution near neurovascular structures and in low‑BMI or post‑weight‑loss patients."}},{"doi":"10.1016/j.jaad.2022.08.068","pmid":"36623556","title":"Executive summary: American Academy of Dermatology guidelines of care for the management of atopic dermatitis in adults with topical therapies","journal_title":"Journal of the American Academy of Dermatology","journal_issn":"0190-9622","published_at":"2023-01-10T00:00:00.000Z","url":"https://doi.org/10.1016/j.jaad.2022.08.068","source_score":354,"is_retracted":false,"is_open_access":false,"raw_metadata":{"ooir":{"day":"2023-02-03","doi":"10.1016/j.jaad.2022.08.068","days":"30","issn":"0190-9622","rank":"2","field":"Clinical Medicine","score":"354","category":"Dermatology","categories":["Dermatology"],"_categories":["Dermatology"]},"pubmed":{"doi":"10.1016/j.jaad.2022.08.068","title":"Executive summary: American Academy of Dermatology guidelines of care for the management of atopic dermatitis in adults with topical therapies.","journal":"Journal of the American Academy of Dermatology","methods":"","results":"","abstract":"These guidelines update the 2014 recommendations for management of atopic dermatitis in adults with topical therapies. A multidisciplinary workgroup employed best practices for guideline development, including a systematic review of the evidence and application of the Grading of Recommendations, Assessment, Development, and Evaluation approach for assessing the certainty of the evidence and formulating and grading recommendations. The evidence on atopic dermatitis treatment supported strong recommendations for the use of nonprescription moisturizers, topical calcineurin inhibitors, topical corticosteroids, and topical PDE-4 and JAK inhibitors. Conditional recommendations are made for the use of bathing and wet wrap therapy and against the use of topical antimicrobials, antiseptics, and antihistamines.","keywords":["JAK inhibitor","antihistamines","antimicrobials","atopic dermatitis","bathing","calcineurin inhibitors","corticosteroids","emollients","topicals","wet wraps"],"pubmed_id":"36623556","conclusions":"","publication_date":"2023-01-10T00:00:00"},"crossref":{"DOI":"10.1016/j.jaad.2022.08.068","URL":"https://doi.org/10.1016/j.jaad.2022.08.068","ISSN":["0190-9622"],"link":[{"URL":"https://api.elsevier.com/content/article/PII:S0190962223000567?httpAccept=text/xml","content-type":"text/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https://api.elsevier.com/content/article/PII:S0190962223000567?httpAccept=text/plain","content-type":"text/plain","content-version":"vor","intended-application":"text-mining"}],"page":"128-129","type":"journal-article","issue":"1","score":1,"title":["Executive summary: American Academy of Dermatology guidelines of care for the management of atopic dermatitis in adults with topical therapies"],"author":[{"given":"Robert","family":"Sidbury","sequence":"first","affiliation":[]},{"given":"Ali","family":"Alikhan","sequence":"additional","affiliation":[]},{"given":"Lionel","family":"Bercovitch","sequence":"additional","affiliation":[]},{"given":"David E.","family":"Cohen","sequence":"additional","affiliation":[]},{"given":"Jennifer M.","family":"Darr","sequence":"additional","affiliation":[]},{"given":"Aaron M.","family":"Drucker","sequence":"additional","affiliation":[]},{"given":"Lawrence F.","family":"Eichenfield","sequence":"additional","affiliation":[]},{"given":"Lindsy","family":"Frazer-Green","sequence":"additional","affiliation":[]},{"given":"Amy S.","family":"Paller","sequence":"additional","affiliation":[]},{"given":"Kathryn","family":"Schwarzenberger","sequence":"additional","affiliation":[]},{"given":"Jonathan I.","family":"Silverberg","sequence":"additional","affiliation":[]},{"given":"Anne Marie","family":"Singh","sequence":"additional","affiliation":[]},{"given":"Peggy A.","family":"Wu","sequence":"additional","affiliation":[]},{"given":"Dawn M.R.","family":"Davis","sequence":"additional","affiliation":[]}],"funder":[{"id":[{"id":"10.13039/100001934","id-type":"DOI","asserted-by":"publisher"}],"DOI":"10.13039/100001934","name":"American Academy of Dermatology","doi-asserted-by":"publisher"}],"issued":{"date-parts":[[2023,7]]},"member":"78","prefix":"10.1016","source":"Crossref","volume":"89","created":{"date-time":"2023-01-07T01:16:02Z","timestamp":1673054162000,"date-parts":[[2023,1,7]]},"indexed":{"date-time":"2025-08-27T16:01:29Z","timestamp":1756310489308,"date-parts":[[2025,8,27]]},"license":[{"URL":"https://www.elsevier.com/tdm/userlicense/1.0/","start":{"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000,"date-parts":[[2023,7,1]]},"delay-in-days":0,"content-version":"tdm"}],"subject":[],"abstract":null,"language":"en","relation":{},"resource":{"primary":{"URL":"https://linkinghub.elsevier.com/retrieve/pii/S0190962223000567"}},"subtitle":[],"assertion":[{"name":"publisher","label":"This article is maintained by","value":"Elsevier"},{"name":"articletitle","label":"Article Title","value":"Executive summary: American Academy of Dermatology guidelines of care for the management of atopic dermatitis in adults with topical therapies"},{"name":"journaltitle","label":"Journal Title","value":"Journal of the American Academy of Dermatology"},{"name":"articlelink","label":"CrossRef DOI link to publisher maintained version","value":"https://doi.org/10.1016/j.jaad.2022.08.068"},{"name":"associatedlink","label":"CrossRef DOI link to the associated document","value":"https://doi.org/10.1016/j.jaad.2022.12.029"},{"name":"content_type","label":"Content Type","value":"article"},{"name":"copyright","label":"Copyright","value":"© 2023 by the American Academy of Dermatology, Inc."}],"deposited":{"date-time":"2023-12-09T08:46:23Z","timestamp":1702111583000,"date-parts":[[2023,12,9]]},"issn-type":[{"type":"print","value":"0190-9622"}],"published":{"date-parts":[[2023,7]]},"publisher":"Elsevier BV","reference":[{"DOI":"10.1016/j.jaad.2014.03.023","key":"10.1016/j.jaad.2022.08.068_bib1","year":"2014","issue":"1","author":"Eichenfield","volume":"71","first-page":"116","unstructured":null,"article-title":"Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies","journal-title":"J Am Acad Dermatol","doi-asserted-by":"crossref"}],"short-title":[],"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,7]]}},"update-policy":"https://doi.org/10.1016/elsevier_cm_policy","alternative-id":["S0190962223000567"],"content-domain":{"domain":["clinicalkey.fr","jaad.org","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"original-title":[],"container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2023,7]]},"reference-count":1,"published-online":null,"references-count":1,"short-container-title":["Journal of the American Academy of Dermatology"],"is-referenced-by-count":10},"unpaywall":{"doi":"10.1016/j.jaad.2022.08.068","is_oa":false,"title":"Executive summary: American Academy of Dermatology guidelines of care for the management of atopic dermatitis in adults with topical therapies","updated":"2025-05-22T18:42:22+00:00","published_date":"2023-01-07","best_oa_location":null}},"created_at":"2025-09-22T04:00:58.889Z","updated_at":"2025-09-22T14:20:55.574Z","tags":[{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"age_group","value":"adult","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"category","value":"Dermatology","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"condition","value":"Atopic Dermatitis","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"Bathing","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"JAK Inhibitor","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"Moisturizer","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"PDE-4 Inhibitor","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"Topical Antihistamine","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"Topical Antimicrobial","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"Topical Antiseptic","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"Topical Calcineurin Inhibitor","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"Topical Corticosteroid","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"modality","value":"Wet Wrap Therapy","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"study_design","value":"Guideline","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"warning","value":"Design is a guideline based on a systematic review rather than a primary comparative study.","value_numeric":null},{"paper_doi":"10.1016/j.jaad.2022.08.068","tag_type":"warning","value":"Only summary-level details were available; no numeric effect sizes or graded certainty levels are provided in the text.","value_numeric":null}],"summaries":{"what_studied":"Updated guidelines for managing atopic dermatitis in adults using topical therapies, based on a systematic review and GRADE methodology to assess evidence and make recommendations.","key_result":"Strong recommendations were made for nonprescription moisturizers, topical calcineurin inhibitors, topical corticosteroids, and topical PDE-4 and JAK inhibitors; conditional recommendations were made for bathing and wet wrap therapy and against topical antimicrobials, antiseptics, and antihistamines.","practice_takeaway":"For adult atopic dermatitis, prioritize moisturizers and guideline-supported topicals (corticosteroids, calcineurin inhibitors, PDE-4 and JAK inhibitors); consider bathing and wet wraps selectively, and avoid topical antimicrobials, antiseptics, and antihistamines."}}],"initialOffset":10,"fetchConfig":{"kind":"tags","tags":[{"tag_type":"study_design","value":"Guideline"}]},"breadcrumbItems":[{"name":"Home","href":"/"},{"name":"Research Hub","href":"/hub"},{"name":"Study Designs","href":"/hub/tag/study_design"},{"name":"Guideline"}],"hrefConfig":{"basePath":"/hub/papers","webViewQueryParams":{"hub_ctx":"tag","hub_tag_type":"study_design","hub_tag_value":"Guideline"}}}]]

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