Systemic therapy, gastrectomy, cytoreductive surgery, and hyperthermic intraperitoneal chemotherapy versus systemic therapy alone for gastric cancer with limited peritoneal metastases (PERISCOPE II): final results of a multicentre, randomised, controlled, phase 3 trial after an unplanned commissioned interim analysis

Study limitation reported by the research below: “Level of evidence tagged as 2 (phase 3 RCT closed early); some would classify early-stopped RCTs at a lower level due to imprecision.”