Systemic therapy, gastrectomy, cytoreductive surgery, and hyperthermic intraperitoneal chemotherapy versus systemic therapy alone for gastric cancer with limited peritoneal metastases (PERISCOPE II): final results of a multicentre, randomised, controlled, phase 3 trial after an unplanned commissioned interim analysis

Study limitation reported by the research below: “Trial was stopped early due to an unplanned commissioned futility interim analysis, which introduces the possibility of an underpowered estimate; the confidence interval is wide and does not exclude modest benefit or harm.”