ReachRxResearch
Home
Research
Sign Up
Polypharmacy and Drug-Drug Interactions Among Older Adults
Back to Research Hub
  1. Home
  2. Research Hub
  3. Polypharmacy and Drug-Drug Interactions…

Polypharmacy and Drug-Drug Interactions Among Older Adults

JAMA·September 24Open Access
Medicine, General & InternalLimited evidenceDrug-Drug InteractionsPolypharmacyCross-Sectional StudyOlder Adult

Summary

View source

What was studied

Changes in use of prescription drugs, OTC medications, and dietary supplements — and potentially major drug-drug interactions (DDIs) — among older adults in the US, comparing 2015–2016 with 2021–2023, using a nationally representative sample.

Key findings

No specific numerical results are available in the provided source text; the full text is not accessible (publisher page only).

Study limitations

Full text is behind a paywall and not provided, so specific findings, effect sizes, and methodological details cannot be assessed.

Clinical implications

Clinicians caring for older adults should routinely screen for polypharmacy across prescription, OTC, and supplement use, as concurrent use and DDI risk appear to be an ongoing and evolving concern in this population.

Caveats

  • Conflict of interest disclosures include paid consulting and equity holdings among senior authors, which may warrant scrutiny when interpreting conclusions
  • The full text of this article is not publicly available; only the publisher landing page and abstract were provided. No quantitative results, sample size, or detailed methods could be extracted
  • The PMC full text will not be available until March 24, 2027, meaning findings cannot yet be independently verified from the source

Related Questions

Explore related topics

How common are major drug-drug interactions in older adults taking multiple medications?What tools can clinicians use to screen for polypharmacy and drug interactions in elderly patients?How has over-the-counter and dietary supplement use changed among older adults in recent years?

Publication Details

Year
2026
Journal
JAMA
Source
View article
Keep scrolling
More content below.
Up Next