Changes in use of prescription drugs, OTC medications, and dietary supplements — and potentially major drug-drug interactions (DDIs) — among older adults in the US, comparing 2015–2016 with 2021–2023, using a nationally representative sample.
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Clinicians caring for older adults should routinely screen for polypharmacy across prescription, OTC, and supplement use, as concurrent use and DDI risk appear to be an ongoing and evolving concern in this population.
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