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When to Use the HINTS Examination in Patients With Dizziness
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When to Use the HINTS Examination in Patients With Dizziness

JAMA Neurology·September 21
Clinical NeurologyPractice changingAcute Vestibular SyndromeDizzinessStrokeNarrative ReviewBedside Neurological ExaminationAdult

Summary

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What was studied

This review examines the proper indications and common misapplications of the HINTS examination (Head Impulse, Nystagmus, Test of Skew) for distinguishing peripheral vestibular disorders from central causes (e.g., stroke) in patients presenting with acute vestibular syndrome.

Key findings

HINTS has high sensitivity for stroke detection when applied correctly — specifically to patients with continuous dizziness and spontaneous nystagmus at rest — but diagnostic accuracy declines significantly when used in patients without nystagmus or without prior screening for central features.

Study limitations

This is a narrative review without a systematic search or meta-analysis, so effect size estimates for misapplication are not quantified. The critique of GRACE-3 guidelines reflects the authors' interpretation rather than empirical data.

Clinical implications

Before performing HINTS, first screen for central features and confirm the patient has spontaneous nystagmus at rest — if there is no nystagmus, do not use HINTS. Reserving HINTS for the correct population (acute vestibular syndrome with continuous dizziness and resting nystagmus) is essential to avoid missed strokes or unnecessary imaging.

Caveats

  • Findings apply specifically to patients with acute vestibular syndrome and spontaneous resting nystagmus; generalizability to broader dizzy populations is explicitly cautioned against by the authors
  • The paper's critique of the GRACE-3 guidelines is interpretive and may reflect the authors' viewpoint rather than a consensus position
  • This is a narrative review and does not present original data; quantitative accuracy estimates cited are drawn from prior studies without a formal systematic search or pooled analysis

Related Questions

Explore related topics

How do I correctly perform the HINTS exam to rule out stroke in dizzy patients?What are the sensitivity and specificity of HINTS for posterior circulation stroke in acute vestibular syndrome?What does GRACE-3 recommend for evaluation of dizziness in the emergency department?

Publication Details

Year
2026
Journal
JAMA Neurology
Source
View article
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