An international expert consensus process evaluating the contemporary role of pelvic exenteration in the management of recurrent or persistent cervical cancer, including patient selection, surgical technique, and integration with systemic therapies.
Experts reached consensus that pelvic exenteration remains the primary potentially curative option for selected patients with recurrent or persistent cervical cancer confined to the pelvis, with careful patient selection and multidisciplinary evaluation identified as critical determinants of outcome.
Consensus-based methodology relies on expert opinion rather than prospective trial data; recommendations may reflect institutional bias given variation in exenteration volume and experience across contributing centers.
Pelvic exenteration should be considered for fit patients with locoregionally confined recurrent or persistent cervical cancer after multidisciplinary review; the decision should weigh surgical morbidity against the lack of other curative-intent options.
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