Advances in Skin &amp; Wound Care

<jats:title>ABSTRACT</jats:title>
          <jats:sec>
            <jats:title>OBJECTIVE</jats:title>
            <jats:p>To review the literature to determine whether compression therapies and nutrition status influence venous ulcer healing.</jats:p>
          </jats:sec>
          <jats:sec>
            <jats:title>DATA SOURCE</jats:title>
            <jats:p>A systematized bibliographic review was carried out by searching PubMed, Scopus, and Cochrane databases for studies published between 2015 and 2020, using descriptors in Spanish and English.</jats:p>
          </jats:sec>
          <jats:sec>
            <jats:title>STUDY SELECTION</jats:title>
            <jats:p>After establishing the research question and applying the filters based on inclusion and exclusion criteria, 114 articles were found. After screening, 11 articles were selected for the review: 8 were identified in the literature search, and 3 were added from the bibliographic references of other studies.</jats:p>
          </jats:sec>
          <jats:sec>
            <jats:title>DATA EXTRACTION</jats:title>
            <jats:p>The authors developed a data extraction sheet that recorded the following variables: author, country, year of publication, level of evidence, research design, therapy type, initial ulcer size, active ulcer history, pain, healed wounds, wound reduction, therapy tolerance, nutrition assessment method, body mass index, and nutrition disorders.</jats:p>
          </jats:sec>
          <jats:sec>
            <jats:title>DATA SYNTHESIS</jats:title>
            <jats:p>Four studies analyzed the relationship between nutrition status and venous ulcer healing, finding that these patients tend to have a high body mass index; a deficit of nutrients such as vitamin A, D, or zinc; and an excess of lipids and carbohydrates. Seven studies compared different types of compression to determine which provided the best results, with two- and four-layer therapy being the most commonly used. Variables such as small wound size and recent onset were associated with better prognosis.</jats:p>
          </jats:sec>
          <jats:sec>
            <jats:title>CONCLUSIONS</jats:title>
            <jats:p>In terms of nutrition, the parameters analyzed are very limited. Although several studies show that two-layer therapy produces the greatest ulcer healing, there is not enough information to recommend one type of therapy over the other. Therefore, more clinical trials are needed to study broader nutrition parameters and compare the types of therapy under matched conditions to determine their influence on ulcer healing.</jats:p>
          </jats:sec>

Why venous leg ulcers have difficulty healing: overview on pathophysiology, clinical consequences, and treatment

J Clin Med

What’s new: management of venous leg ulcers: approach to venous leg ulcers

J Am Acad Dermatol

Prevalence and clinical characteristics of chronic venous disease in patients seen in primary care in Spain: results of the international study Vein Consult Program

Cir Esp

Overview of guidelines for the prevention and treatment of venous leg ulcers: a US perspective

J Multidiscip Healthc

Venous ulcers: diagnosis and treatment

Am Fam Physician

Effects and associations of nutrition in patients with venous leg ulcers: a systematic review

J Adv Nurs

Nutrition in wound care management: a comprehensive overview

Wounds

Vitamin D and skin repair: a prospective, double-blind and placebo controlled study in the healing of leg ulcers

Rev Col Bras Cir

Vitamin D deficiency in patients with chronic venous ulcers

Factors associated with poor healing and recurrence of venous ulceration

Plast Reconstr Surg

Nutritional support in the treatment and prevention of pressure ulcers: an overview of studies with an arginine enriched oral nutritional supplement

J Tissue Viability

Nutritional status and food intake in nine patients with chronic low-limb ulcers and pressure ulcers: importance of oral supplements

Nutrition

Understanding the role of nutrition and wound healing

Nutr Clin Pract

PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation

Ann Intern Med

Hierarchy of evidence: levels of evidence and grades of recommendation from current use [in Spanish]

Rev Chilena Infectol

Clinical and cost-effectiveness of compression hosiery versus compression bandages in treatment of venous leg ulcers (Venous Leg Ulcer Study IV, VenUS IV): a randomised controlled trial

Lancet

A comparative clinical study on five types of compression therapy in patients with venous leg ulcers

Int J Med Sci

Adjustable compression wrap devices are cheaper and more effective than inelastic bandages for venous leg ulcer healing. A multicentric Italian randomized clinical experience

Phlebology

Efficacy of two compression systems in the management of VLUs: results of a European RCT

J Wound Care

Clinical superiority of an innovative two-component compression system versus four-component compression system in treatment of active venous leg ulcers: a randomized trial

Clinical outcomes and cost-effectiveness of three different compression systems in newly-diagnosed venous leg ulcers in the UK

Nutrition status in patients with wounds: a cross-sectional analysis of 50 patients with chronic leg ulcers or acute wounds

Eur J Dermatol

Anthropometric, biochemical, and food consumption parameters are associated with venous leg ulcer area and duration

Adv Skin Wound Care

Nutritional profile of older adults with chronic venous leg ulcers: a pilot study

Geriatr Nurs

The effectiveness of a four-layer compression bandage system in comparison with class 3 compression hosiery on healing and quality of life in patients with venous leg ulcers: a randomised controlled trial

Int Wound J

The effectiveness of a specialised oral nutrition supplement on outcomes in patients with chronic wounds: a pragmatic randomised study

J Hum Nutr Diet

The role of nutrition for pressure injury prevention and healing: the 2019 international clinical practice guideline recommendations

Tratamiento nutricional en ulceras por presión y ulceras venosas

Rev Chi Nutr

Body mass index and outcomes in critically injured blunt trauma patients: weighing the impact

J Am Coll Surg

Patients with chronic leg ulcers show diminished levels of vitamins A and E, carotenes, and zinc

Dermatol Surg

Compression bandages or stockings versus no compression for treating venous leg ulcers

Cochrane Database Syst Rev

To review the literature to determine whether compression therapies and nutrition status influence venous ulcer healing.
A systematized bibliographic review was carried out by searching PubMed, Scopus, and Cochrane databases for studies published between 2015 and 2020, using descriptors in Spanish and English.
After establishing the research question and applying the filters based on inclusion and exclusion criteria, 114 articles were found. After screening, 11 articles were selected for the review: 8 were identified in the literature search, and 3 were added from the bibliographic references of other studies.
The authors developed a data extraction sheet that recorded the following variables: author, country, year of publication, level of evidence, research design, therapy type, initial ulcer size, active ulcer history, pain, healed wounds, wound reduction, therapy tolerance, nutrition assessment method, body mass index, and nutrition disorders.
Four studies analyzed the relationship between nutrition status and venous ulcer healing, finding that these patients tend to have a high body mass index; a deficit of nutrients such as vitamin A, D, or zinc; and an excess of lipids and carbohydrates. Seven studies compared different types of compression to determine which provided the best results, with two- and four-layer therapy being the most commonly used. Variables such as small wound size and recent onset were associated with better prognosis.
In terms of nutrition, the parameters analyzed are very limited. Although several studies show that two-layer therapy produces the greatest ulcer healing, there is not enough information to recommend one type of therapy over the other. Therefore, more clinical trials are needed to study broader nutrition parameters and compare the types of therapy under matched conditions to determine their influence on ulcer healing.

Influence of Nutrition Status and Compression Therapy on Venous Ulcer Healing: A Systematic Review.

Influence of Nutrition Status and Compression Therapy on Venous Ulcer Healing: A Systematic Review

Papers