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Adverse policing as a social exposome pathway: Implications for depression, cognition, and dementia risk
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Adverse policing as a social exposome pathway: Implications for depression, cognition, and dementia risk

Alzheimer's & Dementia·August 31Open Access
Clinical NeurologyLimited evidenceAlzheimer'S Disease And Related DementiasCognitive ImpairmentDementia RiskDepressionCross-Sectional Factor Analysis (Exploratory And Confirmatory) Using Longitudinal Cohort DataOlder Adult

Summary

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What was studied

This study examined whether depressive symptoms and cognitive performance remain distinct or show dimensional overlap among older Black adults (n=265, mean age=69, 72% women) in the Health and Retirement Study (2006–2020), stratified by three types of adverse policing exposure: historical lynching, disproportionate state-level police killings, and self-reported lifetime negative law enforcement encounters.

Key findings

Depressive and cognitive items mostly loaded onto separate factors across all exposure groups, but effort-related depressive items ('felt activities were efforts,' 'felt unmotivated') and executive-function cognitive tasks (serial 7s, backwards counting) consistently cross-loaded, especially among those exposed to state-level police killings (3-factor solution) and those with all three adverse policing exposures (n=20; highest depressive symptoms mean=2.15, lowest cognitive scores mean=13.40, poorest model fit overall).

Study limitations

- Very small subgroups (n=20 for cumulative exposure, n=36 for individual-level encounters) limit stability and generalizability of factor solutions. - Anxiety, hypervigilance, and trauma-related symptoms were not measured, so cross-loading patterns cannot be cleanly attributed to depression versus trauma responses. - All CFA models showed poor-to-marginal absolute fit (RMSEA, TLI, CFI), so findings are exploratory and hypothesis-generating only.

Clinical implications

Standard depression and cognitive screening tools (CES-D, modified TICS) may not cleanly separate depressive from cognitive symptoms in older Black adults with chronic exposure to adverse policing—clinicians should interpret effort- and motivation-related items with caution in this population. Incorporating structural racism exposures into dementia risk assessments may improve diagnostic equity.

Caveats

  • Adverse policing exposure variables are heterogeneous (historical/ecological vs. self-reported/individual), and exposures are not mutually exclusive, complicating causal inference.
  • Several CFA models yielded impossible or extreme factor loadings (e.g., values >1.0 in Table 2), suggesting potential estimation instability in small subgroups—interpret structural findings with caution.
  • Study design is primarily psychometric (EFA/CFA) rather than a clinical intervention or prospective cohort outcome study; level of evidence reflects this exploratory nature.
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  • The sample is exclusively older Black adults from the HRS; findings cannot be generalized to other racial/ethnic groups or age cohorts.

Related Questions

Explore related topics

How does structural racism affect cognitive assessment validity in older Black adults?What is the relationship between adverse policing exposure and dementia risk in aging populations?How should clinicians interpret CES-D and cognitive screening results in patients with chronic psychosocial stress?

Publication Details

Year
2026
Journal
Alzheimer's & Dementia
Sample Size
n=265
Source
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