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From Polycystic Ovary Syndrome to Polyendocrine Metabolic Ovarian Syndrome: A Systematic Search and Historical Account of the Renaming of PCOS

Fertility and Sterility·September 1
Obstetrics & GynecologyPractice changingPolycystic Ovary SyndromePolyendocrine Metabolic Ovarian SyndromeSystematic ReviewAdult

Summary

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What was studied

This systematic review traced the historical efforts to rename polycystic ovary syndrome (PCOS) to polyendocrine metabolic ovarian syndrome (PMOS), screening 30 eligible papers (1995–2026) via PRISMA 2020 methodology across Medline and Embase.

Key findings

A 2026 global, patient-co-led renaming process involving 56 organisations and 22,000+ survey respondents achieved 97% consensus on the new name PMOS, with early adoption seen across coding systems, clinical guidelines, professional societies, and media.

Study limitations

The review relies on published literature only (30 papers), which may underrepresent grey literature or unpublished stakeholder efforts; the long-term impact of the rename on clinical outcomes and diagnostic rates has not yet been evaluated.

Clinical implications

Clinicians should begin adopting the term PMOS in practice, documentation, and patient communication, as the rename reflects the broader endocrine-metabolic nature of the condition and has achieved near-universal consensus. Awareness of the updated terminology will be important for coding, referrals, and patient education.

Caveats

  • The DOI format references a future publication date (2026); today's date is confirmed as September 10, 2026, so the paper is current but very recently published.
  • The sample size tag (n=30) refers to eligible papers included in the systematic review, not individual patients. The broader survey involved 22,000+ respondents but is not a clinical trial population.
  • This paper was published in 2026 and references a consensus process completed in 2026; clinical implementation is still in early stages and long-term outcome data are not yet available.

Related Questions

Explore related topics

What are the diagnostic criteria for PMOS (formerly PCOS) after the 2026 renaming?How does the PMOS name change affect ICD coding and clinical documentation?What are the metabolic and endocrine features that distinguish PMOS from the old PCOS framework?

Publication Details

Year
2026
Journal
Fertility and Sterility
Sample Size
n=30
Source
View article
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