A Single-Center, Blinded, Split-Body, Randomized Clinical Trial of High-Intensity, Parallel Ultrasound Beams Versus Microfocused Ultrasound With Visualization for the Treatment of Upper Inner Arm Skin Laxity

Dermatologic Surgery

Clinical Summary

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What was studied

A prospective, single-center, blinded, split-body, randomized clinical study compared a single treatment of high-intensity, parallel beam ultrasound (HIUS) versus microfocused ultrasound with visualization (MFU-V) for upper arm skin laxity/crepiness in 14 female subjects, with assessments at Days 30 and 90 versus baseline.

Key findings

HIUS was as effective as MFU-V in improving arm laxity/crepiness at Day 90; investigators and subjects reported improvement, most subjects were satisfied, pain scores did not differ, and MFU-V required more procedure time.

Study limitations

Very small, single-center sample (n=14), all female; short follow-up limited to 30–90 days after a single treatment session.

Clinical implications

In this small split-body RCT, HIUS achieved similar improvement and pain scores as MFU-V for upper arm laxity/crepiness at 90 days, while taking less time to perform.