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Skin Research and Technology

<jats:title>Abstract</jats:title><jats:sec><jats:title>Introduction</jats:title><jats:p>Improvement of skin barrier strength could lead to healthy and youthful appearance. “Beauty inside‐out” approach using nutraceuticals such as tomato derived carotenoids to support skin barrier strength could be of benefit to the ageing population.</jats:p></jats:sec><jats:sec><jats:title>Method</jats:title><jats:p>A panel of 60 female subjects were provided with the Lumenato capsules (containing carotenoids) or placebo capsules as nutritional supplements for 3 months. Skin health and barrier function were observed using evaporimeter which measures trans epidermal water loss (TEWL). Barrier strength was determined by study of the number of strippings required to disrupt skin barrier and barrier repair was observed in terms of TEWL a few hours after barrier disruption. Cutometer was used to observe skin firmness and elasticity. Measurements were obtained before treatment and after 4 and 12 weeks of use.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Results indicated a statistically significant improvement (<jats:italic>p</jats:italic> &lt; 0.05) in skin barrier strength; a higher number of strippings were required to disrupt skin barrier after 12 weeks of supplement use. There was also a significant improvement in skin firmness and elasticity as observed with a cutometer.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Based on the confines and conditions of this study, oral supplementation with Lumenato resulted in significant improvement in skin barrier as well as skin firmness and elasticity.</jats:p></jats:sec>

publication_history

received

accepted

published

The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease‐affected skin

J Clin Aesthet Dermatol

Understanding the epidermal barrier in healthy and compromised skin: clinically relevant information for the dermatology practitioner proceedings of an expert panel roundtable meeting

Supp J Clin Aesthetic Derm

Natural moisturizing factors (NMF) in the stratum corneum (SC). I. Effects of lipid extraction and soaking

J Cosmet Sci

Effect of oral supplement “Lycopene” on reducing the signs of skin ageing

Clin Pharmacol Biopharm

Effects of golden tomato extract on skin appearance‐outlook into gene expression in cultured dermal fibroblasts and on trans‐epidermal water loss and skin barrier in human subjects

J Cosmet Dermatol

Effect of Lumenato oral supplementation on plasma carotenoid levels and improvement of visual and experiential skin attributes

Skin hydration assessment through modern non‐invasive bioengineering technologies

Maedica (Buchar)

Improvement of skin barrier strength could lead to healthy and youthful appearance. "Beauty inside-out" approach using nutraceuticals such as tomato derived carotenoids to support skin barrier strength could be of benefit to the ageing population.
A panel of 60 female subjects were provided with the Lumenato capsules (containing carotenoids) or placebo capsules as nutritional supplements for 3 months. Skin health and barrier function were observed using evaporimeter which measures trans epidermal water loss (TEWL). Barrier strength was determined by study of the number of strippings required to disrupt skin barrier and barrier repair was observed in terms of TEWL a few hours after barrier disruption. Cutometer was used to observe skin firmness and elasticity. Measurements were obtained before treatment and after 4 and 12 weeks of use.
Results indicated a statistically significant improvement (p < 0.05) in skin barrier strength; a higher number of strippings were required to disrupt skin barrier after 12 weeks of supplement use. There was also a significant improvement in skin firmness and elasticity as observed with a cutometer.
Based on the confines and conditions of this study, oral supplementation with Lumenato resulted in significant improvement in skin barrier as well as skin firmness and elasticity.

Effect of Lumenato a Tomato derived oral supplement on improving skin barrier strength.

Effect of Lumenato a Tomato derived oral supplement on improving skin barrier strength

Effect of Lumenato a Tomato derived oral supplement on improving skin barrier strength

Clinical Summary

What was studied

Key findings

Study limitations

Clinical implications

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